| Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ... Science 324 (5933), 1457-1461, 2009 | 3524 | 2009 |
| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011 | 2274 | 2011 |
| In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma FA Karreth, Y Tay, D Perna, U Ala, SM Tan, AG Rust, G DeNicola, ... Cell 147 (2), 382-395, 2011 | 728 | 2011 |
| The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis CE Massie, A Lynch, A Ramos‐Montoya, J Boren, R Stark, L Fazli, ... The EMBO journal 30 (13), 2719-2733, 2011 | 698 | 2011 |
| NRF2 regulates serine biosynthesis in non-small cell lung cancer GM DeNicola, PH Chen, E Mullarky, JA Sudderth, Z Hu, D Wu, H Tang, ... Nature genetics 47 (12), 1475, 2015 | 665 | 2015 |
| Connecting copper and cancer: from transition metal signalling to metalloplasia EJ Ge, AI Bush, A Casini, PA Cobine, JR Cross, GM DeNicola, QP Dou, ... Nature Reviews Cancer 22 (2), 102-113, 2022 | 632 | 2022 |
| The complex interplay between antioxidants and ROS in cancer IS Harris, GM DeNicola Trends in cell biology 30 (6), 440-451, 2020 | 435 | 2020 |
| NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer IIC Chio, SM Jafarnejad, M Ponz-Sarvise, Y Park, K Rivera, W Palm, ... Cell 166 (4), 963-976, 2016 | 351 | 2016 |
| Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers E Mullarky, NC Lucki, R Beheshti Zavareh, JL Anglin, AP Gomes, ... Proceedings of the National Academy of Sciences 113 (7), 1778-1783, 2016 | 293 | 2016 |
| The non-essential amino acid cysteine becomes essential for tumor proliferation and survival JA Combs, GM DeNicola Cancers 11 (5), 678, 2019 | 194 | 2019 |
| Dynamic ROS control by TIGAR regulates the initiation and progression of pancreatic cancer EC Cheung, GM DeNicola, C Nixon, K Blyth, CF Labuschagne, ... Cancer cell 37 (2), 168-182. e4, 2020 | 185 | 2020 |
| Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors BM Emerling, JB Hurov, G Poulogiannis, KS Tsukazawa, R Choo-Wing, ... Cell 155 (4), 844-857, 2013 | 182 | 2013 |
| Non-canonical glutamate-cysteine ligase activity protects against ferroptosis YP Kang, A Mockabee-Macias, C Jiang, A Falzone, N Prieto-Farigua, ... Cell metabolism 33 (1), 174-189. e7, 2021 | 180 | 2021 |
| Cancer’s fuel choice: new flavors for a picky eater GM DeNicola, LC Cantley Molecular cell 60 (4), 514-523, 2015 | 156 | 2015 |
| C-Raf Is Required for the Initiation of Lung Cancer by K-RasG12D FA Karreth, KK Frese, GM DeNicola, M Baccarini, DA Tuveson Cancer discovery 1 (2), 128-136, 2011 | 153* | 2011 |
| Oncogenic KRAS induces NIX-mediated mitophagy to promote pancreatic cancer TJ Humpton, B Alagesan, GM DeNicola, D Lu, GN Yordanov, ... Cancer discovery 9 (9), 1268-1287, 2019 | 134 | 2019 |
| Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ... Cell metabolism 29 (5), 1166-1181. e6, 2019 | 127 | 2019 |
| Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer ME Caldwell, GM DeNicola, CP Martins, MA Jacobetz, A Maitra, ... Oncogene 31 (12), 1599-1608, 2012 | 105 | 2012 |
| Proteogenomic landscape of squamous cell lung cancer PA Stewart, EA Welsh, RJC Slebos, B Fang, V Izumi, M Chambers, ... Nature communications 10 (1), 3578, 2019 | 97 | 2019 |
| Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer YP Kang, L Torrente, A Falzone, CM Elkins, M Liu, JM Asara, CC Dibble, ... Elife 8, e45572, 2019 | 90 | 2019 |
