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Harrie Boonen
Harrie Boonen
H. Lundbeck A/S
Verified email at lundbeck.com - Homepage
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Year
Force, membrane potential, and [Ca2+] i during activation of rat mesenteric small arteries with norepinephrine, potassium, aluminum fluoride, and phorbol ester. Effects of …
PE Jensen, A Hughes, HC Boonen, C Aalkjaer
Circulation research 73 (2), 314-324, 1993
671993
Acute and long-term effects of tissue culture on contractile reactivity in renal arteries of the rat.
JG De Mey, MP Uitendaal, HC Boonen, MJ Vrijdag, MJ Daemen, ...
Circulation research 65 (4), 1125-1135, 1989
631989
6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of …
FE Nielsen, TB Bodvarsdottir, A Worsaae, P MacKay, CE Stidsen, ...
Journal of medicinal chemistry 45 (19), 4171-4187, 2002
592002
Optimizing drug discovery by investigative toxicology: current and future trends
M Beilmann, H Boonen, A Czich, G Dear, P Hewitt, T Mow, P Newham, ...
ALTEX-Alternatives to animal experimentation 36 (2), 289-313, 2019
562019
Continuous intravenous infusion of deferoxamine reduces mortality by paraquat in vitamin E-deficient rats
BS Van Asbeck, FC Hillen, HC Boonen, Y De Jong, JA Dormans, ...
Am Rev Respir Dis 139 (3), 769-73, 1989
531989
The evolving role of investigative toxicology in the pharmaceutical industry
F Pognan, M Beilmann, H Boonen, A Czich, G Dear, P Hewitt, T Mow, ...
Nature reviews drug discovery 22 (4), 317-335, 2023
492023
G-proteins are involved in contractile responses of isolated mesenteric resistance arteries to agonists
HCM Boonen, JGR De Mey
Naunyn-Schmiedeberg's archives of pharmacology 342, 462-468, 1990
481990
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines
HCM Boonen, JGR De Mey
European journal of pharmacology 179 (3), 403-412, 1990
471990
Mesenteric small artery changes after vasoconstrictor infusion in young rats
HCM Boonen, MJAP Daemen, PHA Eerdmans, GE Fazzi, EM van Kleef, ...
Journal of cardiovascular pharmacology 22 (3), 388-395, 1993
411993
Synthesis and pharmacological evaluation of 4H-1, 4-benzothiazine-2-carbonitrile 1, 1-dioxide and N-(2-cyanomethylsulfonylphenyl) acylamide derivatives as potential activators …
SC Schou, HC Hansen, TM Tagmose, HCM Boonen, A Worsaae, ...
Bioorganic & medicinal chemistry 13 (1), 141-155, 2005
382005
New 3-alkylamino-4 H-thieno-1, 2, 4-thiadiazine 1, 1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells
FE Nielsen, S Ebdrup, AF Jensen, L Ynddal, TB Bodvarsdottir, C Stidsen, ...
Journal of medicinal chemistry 49 (14), 4127-4139, 2006
332006
Growth responses in isolated elastic, muscular and resistance-sized arterial segments of the rat
JGR De Mey, MP Uitendaal, HCM Boonen, PMH Schiffers, GE Fazzi
Journal of Vascular Research 28 (5), 372-385, 1991
241991
DNA synthesis in isolated arteries. Kinetics and structural consequences
HC Boonen, PM Schiffers, GE Fazzi, GM Janssen, MJ Daemen, ...
American Journal of Physiology-Heart and Circulatory Physiology 260 (1 …, 1991
241991
Arylcyanoguanidines as activators of Kir6. 2/SUR1KATP channels and inhibitors of insulin release
TM Tagmose, SC Schou, JP Mogensen, FE Nielsen, POG Arkhammar, ...
Journal of medicinal chemistry 47 (12), 3202-3211, 2004
172004
Effects of a phorbol ester and staurosporine on electro-and pharmacomechanical coupling in a resistance artery
HCM Boonen, JGR De Mey
European journal of pharmacology 202 (1), 25-32, 1991
151991
In vivo DNA synthesis is not uniformly increased in arterial smooth muscle of young spontaneously hypertensive rats
JGR De Mey, MJAP Daemen, HCM Boonen, FT Bosman, EH Dijkstra, ...
Journal of hypertension 9 (8), 695-701, 1991
151991
Characterization of capsaicin induced responses in mice vas deferens: Evidence of CGRP uptake
M Sheykhzade, S Gupta, T Sørensen, OA Sørensen, H Koch, ...
European journal of pharmacology 667 (1-3), 375-382, 2011
142011
Medicines combinations options and regulatory hurdles
OJ Bjerrum, Y Gautam, EJ Bjerrum, M Schmiegelow, HCM Boonen
European Journal of Pharmaceutical Sciences 49 (4), 659-663, 2013
132013
Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance‐sized arteries
EM Outzen, M Zaki, B Abdolalizadeh, A Sams, HCM Boonen, ...
Pharmacology Research & Perspectives 3 (6), e00200, 2015
112015
Synthesis and biological activity of 3, 3-Diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells
TM Tagmose, F Zaragoza, HCM Boonen, A Worsaae, JP Mogensen, ...
Bioorganic & medicinal chemistry 11 (6), 931-940, 2003
112003
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