| N-Tosyloxycarbamates as a Source of Metal Nitrenes: Rhodium-Catalyzed C−H Insertion and Aziridination Reactions H Lebel, K Huard, S Lectard Journal of the American Chemical Society 127 (41), 14198-14199, 2005 | 343 | 2005 |
| N‐Tosyloxycarbamates as Reagents in Rhodium‐Catalyzed CH Amination Reactions K Huard, H Lebel Chemistry–A European Journal 14 (20), 6222-6230, 2008 | 190 | 2008 |
| De Novo Synthesis of Troc-Protected Amines: Intermolecular Rhodium-Catalyzed C−H Amination with N-Tosyloxycarbamates H Lebel, K Huard Organic Letters 9 (4), 639-642, 2007 | 135 | 2007 |
| Highly efficient synthesis of terminal alkenes from ketones H Lebel, D Guay, V Paquet, K Huard Organic Letters 6 (18), 3047-3050, 2004 | 91 | 2004 |
| Catalytic activation of nitrogen derivatives with transition-metal complexes H Lebel, O Leogane, K Huard, S Lectard Pure and applied chemistry 78 (2), 363-375, 2006 | 78 | 2006 |
| Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5) K Huard, J Brown, JC Jones, S Cabral, K Futatsugi, M Gorgoglione, ... Scientific reports 5 (1), 17391, 2015 | 61 | 2015 |
| Discovery of PF-06835919: a potent inhibitor of ketohexokinase (KHK) for the treatment of metabolic disorders driven by the overconsumption of fructose K Futatsugi, AC Smith, M Tu, B Raymer, K Ahn, SB Coffey, MS Dowling, ... Journal of Medicinal Chemistry 63 (22), 13546-13560, 2020 | 49 | 2020 |
| Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structure DA Griffith, RL Dow, K Huard, DJ Edmonds, SW Bagley, J Polivkova, ... Journal of medicinal chemistry 56 (17), 7110-7119, 2013 | 42 | 2013 |
| Discovery of fragment-derived small molecules for in vivo inhibition of ketohexokinase (KHK) K Huard, K Ahn, P Amor, DA Beebe, KA Borzilleri, BA Chrunyk, SB Coffey, ... Journal of medicinal chemistry 60 (18), 7835-7849, 2017 | 41 | 2017 |
| Optimization of a dicarboxylic series for in vivo inhibition of citrate transport by the solute carrier 13 (SLC13) family K Huard, JR Gosset, JI Montgomery, A Gilbert, MM Hayward, TV Magee, ... Journal of medicinal chemistry 59 (3), 1165-1175, 2016 | 36 | 2016 |
| Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models N Jiménez de Oya, WP Esler, K Huard, AF El-Kattan, G Karamanlidis, ... Emerging microbes & infections 8 (1), 624-636, 2019 | 35 | 2019 |
| Synthesis of spiropiperidine lactam acetyl-CoA carboxylase inhibitors K Huard, SW Bagley, E Menhaji-Klotz, C Préville, JA Southers Jr, ... The Journal of organic chemistry 77 (22), 10050-10057, 2012 | 31 | 2012 |
| Determination of unbound partition coefficient and in vitro–in vivo extrapolation for SLC13A transporter–mediated uptake K Riccardi, Z Li, JA Brown, MF Gorgoglione, M Niosi, J Gosset, K Huard, ... Drug Metabolism and Disposition 44 (10), 1633-1642, 2016 | 29 | 2016 |
| GLP-1 receptor agonists and uses thereof GE Aspnes, SW Bagley, JM Curto, MS Dowling, D Edmonds, ... US Patent 10,208,019, 2019 | 22 | 2019 |
| Molecular basis for inhibition of the Na+/citrate transporter NaCT (SLC13A5) by dicarboxylate inhibitors AM Pajor, CA de Oliveira, K Song, K Huard, V Shanmugasundaram, ... Molecular pharmacology 90 (6), 755-765, 2016 | 21 | 2016 |
| Optimizing the benefit/risk of acetyl-CoA carboxylase inhibitors through liver targeting K Huard, AC Smith, G Cappon, RL Dow, DJ Edmonds, A El-Kattan, ... Journal of Medicinal Chemistry 63 (19), 10879-10896, 2020 | 19 | 2020 |
| Discovery of selective small molecule inhibitors of monoacylglycerol acyltransferase 3 K Huard, AT Londregan, G Tesz, KB Bahnck, TV Magee, D Hepworth, ... Journal of medicinal chemistry 58 (18), 7164-7172, 2015 | 16 | 2015 |
| Substituted 3-azabicyclo [3.1. 0] hexanes as ketohexokinase inhibitors M Dowling, D Fernando, K Futatsugi, K Huard, TV Magee, B Raymer, ... US Patent 9,809,579, 2017 | 15 | 2017 |
| Diacylglycerol acyltransferase 2 inhibitors S Cabral, K Futatsugi, D Hepworth, K Huard, DWS Kung, STM Orr, K Song US Patent 9,440,949, 2016 | 14 | 2016 |
| A multi-endpoint matched molecular pair (MMP) analysis of 6-membered heterocycles G Chang, K Huard, GW Kauffman, AF Stepan, CE Keefer Bioorganic & Medicinal Chemistry 25 (1), 381-388, 2017 | 13 | 2017 |
