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Yu-Wei Lin
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Powder production and particle engineering for dry powder inhaler formulations
YW Lin, J Wong, L Qu, HK Chan, QT Zhou
Current pharmaceutical design 21 (27), 3902-3916, 2015
952015
Bacteriophage uptake by mammalian cell layers represents a potential sink that may impact phage therapy
MC Bichet, WH Chin, W Richards, YW Lin, L Avellaneda-Franco, ...
Iscience 24 (4), 2021
692021
Pharmacokinetics/pharmacodynamics of pulmonary delivery of colistin against Pseudomonas aeruginosa in a mouse lung infection model
YW Lin, QT Zhou, SE Cheah, J Zhao, K Chen, J Wang, HK Chan, J Li
Antimicrobial agents and chemotherapy 61 (3), 10.1128/aac. 02025-16, 2017
642017
Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in Pseudomonas aeruginosa
ML Han, Y Zhu, DJ Creek, YW Lin, AD Gutu, P Hertzog, T Purcell, ...
MSystems 4 (1), 10.1128/msystems. 00149-18, 2019
592019
Alterations of metabolic and lipid profiles in polymyxin-resistant Pseudomonas aeruginosa
ML Han, Y Zhu, DJ Creek, YW Lin, D Anderson, HH Shen, B Tsuji, ...
Antimicrobial agents and chemotherapy 62 (6), 10.1128/aac. 02656-17, 2018
582018
Inhalable liposomal powder formulations for co-delivery of synergistic ciprofloxacin and colistin against multi-drug resistant gram-negative lung infections
S Yu, S Wang, P Zou, G Chai, YW Lin, T Velkov, J Li, W Pan, QT Zhou
International journal of pharmaceutics 575, 118915, 2020
562020
Aerosolized polymyxin B for treatment of respiratory tract infections: determination of pharmacokinetic-pharmacodynamic indices for aerosolized polymyxin B against Pseudomonas …
YW Lin, Q Zhou, NJ Onufrak, V Wirth, K Chen, J Wang, A Forrest, ...
Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 00211-17, 2017
552017
Potential toxicity of polymyxins in human lung epithelial cells
MU Ahmed, T Velkov, YW Lin, B Yun, CJ Nowell, F Zhou, QT Zhou, ...
Antimicrobial agents and chemotherapy 61 (6), 10.1128/aac. 02690-16, 2017
522017
Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance
Y Zhu, J Lu, ML Han, X Jiang, MAK Azad, NA Patil, YW Lin, J Zhao, Y Hu, ...
Advanced Science 7 (15), 2000704, 2020
452020
Co-delivery of ciprofloxacin and colistin in liposomal formulations with enhanced in vitro antimicrobial activities against multidrug resistant Pseudomonas aeruginosa
S Wang, S Yu, Y Lin, P Zou, G Chai, HH Yu, H Wickremasinghe, N Shetty, ...
Pharmaceutical research 35, 1-13, 2018
452018
Metabolomics study of the synergistic killing of polymyxin B in combination with amikacin against polymyxin-susceptible and-resistant Pseudomonas aeruginosa
M Hussein, ML Han, Y Zhu, Q Zhou, YW Lin, REW Hancock, D Hoyer, ...
Antimicrobial Agents and Chemotherapy 64 (1), 10.1128/aac. 01587-19, 2019
362019
Pharmacokinetics/pharmacodynamics of antipseudomonal bacteriophage therapy in rats: a proof-of-concept study
YW Lin, RY Chang, GG Rao, B Jermain, ML Han, JX Zhao, K Chen, ...
Clinical Microbiology and Infection 26 (9), 1229-1235, 2020
342020
Comparative metabolomics reveals key pathways associated with the synergistic killing of colistin and sulbactam combination against multidrug-resistant Acinetobacter baumannii
ML Han, X Liu, T Velkov, YW Lin, Y Zhu, DJ Creek, CK Barlow, HH Yu, ...
Frontiers in Pharmacology 10, 465171, 2019
262019
Lipidomic Analysis of the Outer Membrane Vesicles from Paired Polymyxin-Susceptible and -Resistant Klebsiella pneumoniae Clinical Isolates
R Jasim, ML Han, Y Zhu, X Hu, MH Hussein, YW Lin, Q Zhou, CYD Dong, ...
International Journal of Molecular Sciences 19 (8), 2356, 2018
252018
Novel polymyxin combination with the antiretroviral zidovudine exerts synergistic killing against NDM-producing multidrug-resistant Klebsiella pneumoniae
YW Lin, N Abdul Rahim, J Zhao, ML Han, HH Yu, H Wickremasinghe, ...
Antimicrobial agents and chemotherapy 63 (4), 10.1128/aac. 02176-18, 2019
242019
Composite particle formulations of colistin and meropenem with improved in-vitro bacterial killing and aerosolization for inhalation
S Mangal, H Park, L Zeng, HY Heidi, Y Lin, T Velkov, JA Denman, ...
International journal of pharmaceutics 548 (1), 443-453, 2018
232018
Mechanistic insights from global metabolomics studies into synergistic bactericidal effect of a polymyxin B combination with tamoxifen against cystic fibrosis MDR Pseudomonas …
M Hussein, ML Han, Y Zhu, EK Schneider-Futschik, X Hu, QT Zhou, ...
Computational and structural biotechnology journal 16, 587-599, 2018
232018
Measuring bipolar charge and mass distributions of powder aerosols by a novel tool (BOLAR)
J Wong, YW Lin, PCL Kwok, V Niemelä, J Crapper, HK Chan
Molecular Pharmaceutics 12 (9), 3433-3440, 2015
212015
Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-Resistant Pseudomonas aeruginosa
YW Lin, ML Han, J Zhao, Y Zhu, G Rao, A Forrest, J Song, KS Kaye, ...
Frontiers in Pharmacology 10, 1146, 2019
192019
Understanding the Impacts of Surface Compositions on the In-Vitro Dissolution and Aerosolization of Co-Spray-Dried Composite Powder Formulations for Inhalation
S Mangal, R Xu, H Park, D Zemlyanov, N Shetty, YW Lin, D Morton, ...
Pharmaceutical research 36, 1-15, 2019
192019
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Articles 1–20