| Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors K Nakayama, N Ishida, M Shirane, A Inomata, T Inoue, N Shishido, I Horii, ... Cell 85 (5), 707-720, 1996 | 1935 | 1996 |
| Ubiquitin ligases: cell-cycle control and cancer KI Nakayama, K Nakayama Nature Reviews Cancer 6 (5), 369-381, 2006 | 1749 | 2006 |
| Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice N Motoyama, F Wang, KA Roth, H Sawa, K Nakayama, K Nakayama, ... Science 267 (5203), 1506-1510, 1995 | 1517 | 1995 |
| Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription EH Kobayashi, T Suzuki, R Funayama, T Nagashima, M Hayashi, ... Nature communications 7 (1), 1-14, 2016 | 1404 | 2016 |
| Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study T Yoshitake, Y Kiyohara, I Kato, T Ohmura, H Iwamoto, K Nakayama, ... Neurology 45 (6), 1161-1168, 1995 | 1138 | 1995 |
| The role of diffusion-weighted imaging in patients with brain tumors K Kono, Y Inoue, K Nakayama, M Shakudo, M Morino, K Ohata, K Wakasa, ... American journal of neuroradiology 22 (6), 1081-1088, 2001 | 1074 | 2001 |
| Foxo3a is essential for maintenance of the hematopoietic stem cell pool K Miyamoto, KY Araki, K Naka, F Arai, K Takubo, S Yamazaki, S Matsuoka, ... Cell stem cell 1 (1), 101-112, 2007 | 985 | 2007 |
| Phosphorylation‐dependent degradation of c‐Myc is mediated by the F‐box protein Fbw7 M Yada, S Hatakeyama, T Kamura, M Nishiyama, R Tsunematsu, H Imaki, ... The EMBO journal 23 (10), 2116-2125, 2004 | 908 | 2004 |
| Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication K Nakayama, H Nagahama, YA Minamishima, M Matsumoto, I Nakamichi, ... The EMBO journal, 2000 | 886 | 2000 |
| An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin M Kitagawa, S Hatakeyama, M Shirane, M Matsumoto, N Ishida, K Hattori, ... The EMBO journal 18 (9), 2401-2410, 1999 | 735 | 1999 |
| Essential role for ZAP-70 in both positive and negative selection of thymocytes I Negishi, N Motoyama, K Nakayama, K Nakayama, S Senju, ... Nature 376 (6539), 435-438, 1995 | 662 | 1995 |
| Aberrant cell cycle checkpoint function and early embryonic death in Chk1−/− mice H Takai, K Tominaga, N Motoyama, YA Minamishima, H Nagahama, ... Genes & development 14 (12), 1439-1447, 2000 | 627 | 2000 |
| The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription N Von Der Lehr, S Johansson, S Wu, F Bahram, A Castell, C Cetinkaya, ... Molecular cell 11 (5), 1189-1200, 2003 | 588 | 2003 |
| Mitogenic signalling and the p16INK4a–Rb pathway cooperate to enforce irreversible cellular senescence A Takahashi, N Ohtani, K Yamakoshi, S Iida, H Tahara, K Nakayama, ... Nature cell biology 8 (11), 1291-1297, 2006 | 584 | 2006 |
| Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase G Bornstein, J Bloom, D Sitry-Shevah, K Nakayama, M Pagano, ... Journal of Biological Chemistry 278 (28), 25752-25757, 2003 | 582 | 2003 |
| Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. K Nakayama, K Nakayama, I Negishi, K Kuida, H Sawa, DY Loh Proceedings of the National Academy of Sciences 91 (9), 3700-3704, 1994 | 535 | 1994 |
| Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice K Nakayama, K Nakayama, I Negishi, K Kuida, Y Shinkai, MC Louie, ... Science 261 (5128), 1584-1588, 1993 | 531 | 1993 |
| Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cδ A Miyamoto, K Nakayama, H Imaki, S Hirose, Y Jiang, M Abe, ... Nature 416 (6883), 865-869, 2002 | 505 | 2002 |
| Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase T Kamura, T Hara, M Matsumoto, N Ishida, F Okumura, S Hatakeyama, ... Nature cell biology 6 (12), 1229-1235, 2004 | 497 | 2004 |
| Regulation of the cell cycle by SCF-type ubiquitin ligases KI Nakayama, K Nakayama Seminars in cell & developmental biology 16 (3), 323-333, 2005 | 470 | 2005 |
