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Yi-Chao Zheng
Yi-Chao Zheng
Verified email at zzu.edu.cn
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Year
Triazole–dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration
YC Zheng, YC Duan, JL Ma, RM Xu, X Zi, WL Lv, MM Wang, XW Ye, ...
Journal of medicinal chemistry 56 (21), 8543-8560, 2013
2392013
A systematic review of histone lysine‐specific demethylase 1 and its inhibitors
YC Zheng, J Ma, Z Wang, J Li, B Jiang, W Zhou, X Shi, X Wang, W Zhao, ...
Medicinal research reviews 35 (5), 1032-1071, 2015
2102015
Design, synthesis, and structure–activity relationship of novel LSD1 inhibitors based on pyrimidine–thiourea hybrids as potent, orally active antitumor agents
LY Ma, YC Zheng, SQ Wang, B Wang, ZR Wang, LP Pang, M Zhang, ...
Journal of medicinal chemistry 58 (4), 1705-1716, 2015
1722015
Design, synthesis and antiproliferative activity studies of novel 1, 2, 3-triazole–dithiocarbamate–urea hybrids
YC Duan, YC Zheng, XC Li, MM Wang, XW Ye, YY Guan, GZ Liu, ...
European journal of medicinal chemistry 64, 99-110, 2013
1282013
Natural product-derived spirooxindole fragments serve as privileged substructures for discovery of new anticancer agents
B Yu, YC Zheng, XJ Shi, PP Qi, HM Liu
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2016
1182016
USP7: Novel Drug Target in Cancer Therapy
ZWWKYYJPHRZHSHMLYC Zheng*
Frontiers in Pharmacology, 2019
1062019
Design and synthesis of novel 1, 2, 3-triazole–pyrimidine–urea hybrids as potential anticancer agents
LY Ma, B Wang, LP Pang, M Zhang, SQ Wang, YC Zheng, KP Shao, ...
Bioorganic & Medicinal Chemistry Letters 25 (5), 1124-1128, 2015
1062015
Irreversible LSD1 inhibitors: application of tranylcypromine and its derivatives in cancer treatment
Y C Zheng, B Yu, G Z Jiang, X J Feng, P X He, X Y Chu, W Zhao, H M Liu
Current topics in medicinal chemistry 16 (19), 2179-2188, 2016
992016
Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma
Y Lu, YT Chan, HY Tan, C Zhang, W Guo, Y Xu, R Sharma, ZS Chen, ...
Journal of Experimental & Clinical Cancer Research 41, 1-17, 2022
932022
Synthesis and biological evaluation of coumarin–1, 2, 3-triazole–dithiocarbamate hybrids as potent LSD1 inhibitors
XW Ye, YC Zheng, YC Duan, MM Wang, B Yu, JL Ren, JL Ma, E Zhang, ...
MedChemComm 5 (5), 650-654, 2014
932014
Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment
YC Duan, YC Ma, WP Qin, LN Ding, YC Zheng, YL Zhu, XY Zhai, J Yang, ...
European journal of medicinal chemistry 140, 392-402, 2017
792017
Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach
B Yu, PP Qi, XJ Shi, R Huang, H Guo, YC Zheng, DQ Yu, HM Liu
European Journal of Medicinal Chemistry 117, 241-255, 2016
792016
TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy
YC Zheng, B Yu, ZS Chen, Y Liu, HM Liu
Epigenomics 8 (5), 651-666, 2016
792016
Skp2 in the ubiquitin‐proteasome system: a comprehensive review
MD Asmamaw, Y Liu, YC Zheng, XJ Shi, HM Liu
Medicinal Research Reviews 40 (5), 1920-1949, 2020
762020
Discovery of [1,2,3]Triazolo[4,5-d]pyrimidine Derivatives as Novel LSD1 Inhibitors
ZH Li, XQ Liu, PF Geng, FZ Suo, JL Ma, B Yu, TQ Zhao, ZQ Zhou, ...
ACS Medicinal Chemistry Letters 8 (4), 384-389, 2017
732017
Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)
Z Li, L Ding, Z Li, Z Wang, F Suo, D Shen, T Zhao, X Sun, J Wang, Y Liu, ...
Acta Pharmaceutica Sinica B 9 (4), 794-808, 2019
722019
Design, synthesis and biological evaluation of [1, 2, 4] triazolo [1, 5-a] pyrimidines as potent lysine specific demethylase 1 (LSD1/KDM1A) inhibitors
S Wang, LJ Zhao, YC Zheng, DD Shen, EF Miao, XP Qiao, LJ Zhao, Y Liu, ...
European journal of medicinal chemistry 125, 940-951, 2017
682017
Tranylcypromine based lysine-specific demethylase 1 inhibitor: summary and perspective
XJ Dai, Y Liu, XP Xiong, LP Xue, YC Zheng, HM Liu
Journal of Medicinal Chemistry 63 (23), 14197-14215, 2020
642020
LSD1 deletion decreases exosomal PD-L1 and restores T-cell response in gastric cancer
DD Shen, JR Pang, YP Bi, LF Zhao, YR Li, LJ Zhao, Y Gao, B Wang, ...
Molecular cancer 21 (1), 75, 2022
632022
Development of Highly Potent, Selective, and Cellular Active Triazolo[1,5-a]pyrimidine-Based Inhibitors Targeting the DCN1–UBC12 Protein–Protein Interaction
S Wang, L Zhao, XJ Shi, L Ding, L Yang, ZZ Wang, D Shen, K Tang, XJ Li, ...
Journal of Medicinal Chemistry 62 (5), 2772-2797, 2019
632019
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