Dudley Lamming
Dudley Lamming
Associate Professor of Medicine, University of Wisconsin-Madison
Verified email at - Homepage
Cited by
Cited by
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz, KJ Bitterman, HY Cohen, DW Lamming, S Lavu, JG Wood, ...
Nature 425 (6954), 191-196, 2003
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ...
Science 335 (6076), 1638, 2012
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
H Yang, T Yang, JA Baur, E Perez, T Matsui, JJ Carmona, DW Lamming, ...
Cell 130 (6), 1095-1107, 2007
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ...
Nature 486 (7404), 490-495, 2012
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ...
Nature 531 (7592), 53-58, 2016
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
S Robida-Stubbs, K Glover-Cutter, DW Lamming, M Mizunuma, ...
Cell metabolism 15 (5), 713-724, 2012
Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
BP Hubbard, AP Gomes, H Dai, J Li, AW Case, T Considine, TV Riera, ...
Science 339 (6124), 1216-1219, 2013
Rapalogs and mTOR inhibitors as anti-aging therapeutics
DW Lamming, L Ye, DM Sabatini, JA Baur
The Journal of clinical investigation 123 (3), 980-989, 2013
The TSC-mTOR pathway regulates macrophage polarization
V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ...
Nature communications 4 (1), 2834, 2013
The mechanistic target of rapamycin: the grand conducTOR of metabolism and aging
BK Kennedy, DW Lamming
Cell metabolism 23 (6), 990-1003, 2016
Decreased consumption of branched-chain amino acids improves metabolic health
L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ...
Cell reports 16 (2), 520-530, 2016
A central role for mTOR in lipid homeostasis
DW Lamming, DM Sabatini
Cell metabolism 18 (4), 465-469, 2013
MSN2 and MSN4 Link Calorie Restriction and TOR to Sirtuin-Mediated Lifespan Extension in Saccharomyces cerevisiae
O Medvedik, DW Lamming, KD Kim, DA Sinclair
PLoS biology 5 (10), e261, 2007
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
AJ Covarrubias, HI Aksoylar, J Yu, NW Snyder, AJ Worth, SS Iyer, J Wang, ...
elife 5, e11612, 2016
Molecular mechanisms of dietary restriction promoting health and longevity
CL Green, DW Lamming, L Fontana
Nature Reviews Molecular Cell Biology 23 (1), 56-73, 2022
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer
R Strong, RA Miller, A Antebi, CM Astle, M Bogue, MS Denzel, ...
Aging cell 15 (5), 872-884, 2016
Restoration of metabolic health by decreased consumption of branched‐chain amino acids
NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ...
The Journal of physiology 596 (4), 623-645, 2018
STING senses microbial viability to orchestrate stress-mediated autophagy of the endoplasmic reticulum
J Moretti, S Roy, D Bozec, J Martinez, JR Chapman, B Ueberheide, ...
Cell 171 (4), 809-823. e13, 2017
MicroReview: small molecules that regulate lifespan: evidence for xenohormesis
DW Lamming, JG Wood, DA Sinclair
Molecular microbiology 53 (4), 1003-1009, 2004
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile
EM Mercken, SD Crosby, DW Lamming, L JeBailey, S Krzysik‐Walker, ...
Aging cell 12 (4), 645-651, 2013
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