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Jay Xiaojun Tan
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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
X Gui, H Yang, T Li, X Tan, P Shi, M Li, F Du, ZJ Chen
Nature 567 (7747), 262-266, 2019
8142019
Detection of microbial infections through innate immune sensing of nucleic acids
X Tan, L Sun, J Chen, ZJ Chen
Annual review of microbiology 72, 447-478, 2018
3542018
A kinase-independent role for EGF receptor in autophagy initiation
X Tan, N Thapa, Y Sun, RA Anderson
Cell 160 (1), 145-160, 2015
2362015
Stress-induced EGFR trafficking: mechanisms, functions, and therapeutic implications
X Tan, PF Lambert, AC Rapraeger, RA Anderson
Trends in cell biology 26 (5), 352-366, 2016
1812016
A phosphoinositide signalling pathway mediates rapid lysosomal repair
JX Tan, T Finkel
Nature 609 (7928), 815-821, 2022
1092022
Emerging roles of PtdIns(4,5)P2 – beyond the plasma membrane
X Tan, N Thapa, S Choi, RA Anderson
Journal of cell science 128 (22), 4047-4056, 2015
1032015
Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sorting
Y Sun, AC Hedman, X Tan, NJ Schill, RA Anderson
Developmental cell 25 (2), 144-155, 2013
932013
Mitochondria as intracellular signaling platforms in health and disease
JX Tan, T Finkel
Journal of Cell Biology 219 (5), 2020
862020
PIP kinases define PI4, 5P2 signaling specificity by association with effectors
S Choi, N Thapa, X Tan, AC Hedman, RA Anderson
Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
852015
LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation
X Tan, Y Sun, N Thapa, Y Liao, AC Hedman, RA Anderson
The EMBO journal 34 (4), 475-490, 2015
802015
PtdIns (4, 5) P2 signaling regulates ATG14 and autophagy
X Tan, N Thapa, Y Liao, S Choi, RA Anderson
Proceedings of the National Academy of Sciences 113 (39), 10896-10901, 2016
692016
Phosphatidylinositol phosphate 5-kinase Iγ and phosphoinositide 3-kinase/Akt signaling couple to promote oncogenic growth
N Thapa, S Choi, X Tan, T Wise, RA Anderson
Journal of Biological Chemistry 290 (30), 18843-18854, 2015
452015
The hidden conundrum of phosphoinositide signaling in cancer
N Thapa, X Tan, S Choi, PF Lambert, AC Rapraeger, RA Anderson
Trends in cancer 2 (7), 378-390, 2016
382016
PIP kinases from the cell membrane to the nucleus
M Schramp, A Hedman, W Li, X Tan, R Anderson
Phosphoinositides I: Enzymes of Synthesis and Degradation, 25-59, 2012
372012
Lysosomal quality control: molecular mechanisms and therapeutic implications
H Yang, JX Tan
Trends in Cell Biology 33 (9), 749-764, 2023
232023
Phosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells
N Thapa, S Choi, A Hedman, X Tan, RA Anderson
Journal of Biological Chemistry 288 (48), 34707-34718, 2013
192013
PIPKIγ and talin couple phosphoinositide and adhesion signaling to control the epithelial to mesenchymal transition
N Thapa, X Tan, S Choi, T Wise, RA Anderson
Oncogene 36 (7), 899-911, 2017
162017
Modulation of lysosomal function as a therapeutic approach for coronaviral infections
Y Liu, T Lear, M Larsen, B Lin, Q Cao, I Alfaras, J Kennerdell, L Salminen, ...
Research Square, 2021
112021
Lysosomes in senescence and aging
JX Tan, T Finkel
EMBO reports 24 (11), e57265, 2023
72023
A conserved ion channel function of STING mediates noncanonical autophagy and cell death
J Xun, Z Zhang, B Lv, D Lu, H Yang, G Shang, JX Tan
EMBO reports, 1-26, 2024
62024
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Articles 1–20