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Virender Singh
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Therapeutic implication of L-phenylalanine aggregation mechanism and its modulation by D-phenylalanine in phenylketonuria
V Singh, RK Rai, A Arora, N Sinha, AK Thakur
Scientific reports 4 (1), 1-8, 2014
1032014
Understanding the self-assembly of Fmoc–phenylalanine to hydrogel formation
V Singh, K Snigdha, C Singh, N Sinha, AK Thakur
Soft Matter 11 (26), 5353-5364, 2015
762015
Fmoc-phenylalanine displays antibacterial activity against gram-positive bacteria in gel and solution phases
AY Gahane, P Ranjan, V Singh*, RK Sharma, N Sinha, M Sharma, ...
Soft Matter, DOI: 10.1039/C7SM02317K, 2018
572018
Zinc promotes liquid–liquid phase separation of tau protein
V Singh, L Xu, S Boyko, K Surewicz, WK Surewicz
Journal of Biological Chemistry 295 (18), 5850-5856, 2020
542020
Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux
A Rai, PK Singh, V Singh, V Kumar, R Mishra, AK Thakur, A Mahadevan, ...
Cell Death & Disease 9, Article number: 201, 2018
262018
Biodegradable nanoparticles containing mechanism based peptide inhibitors reduce polyglutamine aggregation in cell models and alleviate motor symptoms in a Drosophila model of …
AS Joshi, V Singh, A Gahane, AK Thakur
ACS Chemical Neuroscience 10 (3), 1603-1614, 2018
172018
Development of mechanism-based antibacterial synergy between Fmoc-phenylalanine hydrogel and aztreonam
AY Gahane, V Singh, A Kumar, AK Thakur
Biomaterials science 8 (7), 1996-2006, 2020
142020
NMR Spectroscopy-based Metabolomics of Drosophila Model of Huntington’s Disease Suggests Altered Cell Energetics
V Singh, RK Sharma, T Athilingam, P Sinha, N Sinha, AK Thakur
Journal of Proteome Research 16 (10), 3863-3872, 2017
122017
Discovery of arginine ethyl ester as polyglutamine aggregation inhibitor: conformational transitioning of Huntingtin N-terminus augments aggregation suppression
V Singh, KA Patel, RK Sharma, PR Patil, AS Joshi, R Parihar, ...
ACS Chemical Neuroscience 10 (9), 3969-3985, 2019
62019
A revised mechanism for (p) ppGpp synthesis by Rel proteins: the critical role of the 2′-OH of GTP
PR Patil, N Vithani, V Singh, A Kumar, B Prakash
Journal of Biological Chemistry 295 (37), 12851-12867, 2020
52020
Fluorescence correlation spectroscopy as a tool to investigate the directionality of proteolysis
B Sengupta, N Das, V Singh, AK Thakur, P Sen
International Journal of Biological Macromolecules 164, 2524-2534, 2020
32020
Osmolytes modulate polyglutamine aggregation in a sequence dependent manner
I Saha, V Singh, G Burra, AK Thakur
Journal of Peptide Science 24 (8-9), e3115, 2018
32018
Calmidazolium chloride and its complex with serum albumin prevent Huntingtin exon1 aggregation
V Singh, RNV Krishna Deepak, B Sengupta, AS Joshi, H Fan, P Sen, ...
Molecular pharmaceutics 15 (8), 3356-3368, 2018
32018
Antibiofilm activity of Fmoc-phenylalanine against Gram-positive and Gram-negative bacterial biofilms
H Singh, A Gahane, V Singh, S Ghosh, A Thakur
The Journal of Antibiotics 74 (6), 407-416, 2021
22021
Optimization of Ion-Dependent Green Synthesis of Fmoc-Amino Acids in Phosphate Buffer
V Singh, RK Sharma, N Sinha, AK Thakur
ChemistrySelect 2 (35), 11826-11831, 2017
22017
A Drosophila model of oral peptide therapeutics for adult Intestinal Stem Cell tumors
A Bajpai, QT Ahmad, HW Tang, N Manzar, V Singh, A Thakur, B Ateeq, ...
Disease Models & Mechanisms, doi: 10.1242/dmm.044420, 2020
12020
Structural polymorphism of amyloid fibrils in cardiac ATTR amyloidosis revealed by cryo-electron microscopy
LS Binh A. Nguyen, Shumaila Afrin, Virender Singh, Yasmin Ahmed, Rose ...
bioRxiv, 2022
2022
Arginine derivatives as polyglutamine aggregation inhibitors
AK Thakur, V Singh
IN Patent 357,676, 2021
2021
A drug screening process and a drug formulation for Huntington’s disease
AK Thakur, V Singh
IN Patent 346,555, 2020
2020
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Articles 1–19