Metabolic heterogeneity in human lung tumors CT Hensley, B Faubert, Q Yuan, N Lev-Cohain, E Jin, J Kim, L Jiang, B Ko, ... Cell 164 (4), 681-694, 2016 | 997 | 2016 |
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport C Yang, B Ko, CT Hensley, L Jiang, AT Wasti, J Kim, J Sudderth, ... Molecular cell 56 (3), 414-424, 2014 | 679 | 2014 |
Metabolic diversity in human non-small cell lung cancer cells PH Chen, L Cai, K Huffman, C Yang, J Kim, B Faubert, L Boroughs, B Ko, ... Molecular cell 76 (5), 838-851. e5, 2019 | 152 | 2019 |
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer J Kim, HM Lee, F Cai, B Ko, C Yang, EL Lieu, N Muhammad, S Rhyne, ... Nature metabolism 2 (12), 1401-1412, 2020 | 95 | 2020 |
Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein RJDB Lei Jiang1,*, Adam Boufersaoui1,6,*, Dinesh Rakheja4,5, Gerardo ... Metabolic Engineering, 2016 | 90* | 2016 |
Functional assessment of lipoyltransferase-1 deficiency in cells, mice, and humans M Ni, A Solmonson, C Pan, C Yang, D Li, A Notzon, L Cai, G Guevara, ... Cell reports 27 (5), 1376-1386. e6, 2019 | 76 | 2019 |
Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells KN Rajagopalan, RA Egnatchik, MA Calvaruso, AT Wasti, MS Padanad, ... Cancer & metabolism 3, 1-12, 2015 | 60 | 2015 |
Loss of a negative regulator of mTORC1 induces aerobic glycolysis and altered fiber composition in skeletal muscle PA Dutchak, SJ Estill-Terpack, AA Plec, X Zhao, C Yang, J Chen, B Ko, ... Cell reports 23 (7), 1907-1914, 2018 | 57 | 2018 |
Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model K Oizel, C Yang, O Renoult, F Gautier, QN Do, N Joalland, X Gao, B Ko, ... Cancer & metabolism 8, 1-11, 2020 | 27 | 2020 |
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors P Pachnis, Z Wu, B Faubert, A Tasdogan, W Gu, S Shelton, A Solmonson, ... Science Advances 8 (35), eabn9550, 2022 | 25 | 2022 |
Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30II accessory protein and the induction of oncogenic cellular transformation by p30II/c-MYC MM Romeo, B Ko, J Kim, R Brady, HC Heatley, J He, CK Harrod, ... Virology 476, 271-288, 2015 | 22 | 2015 |
Metabolic adjustments following glutaminase inhibition by CB-839 in glioblastoma cell lines J De los Santos-Jiménez, T Rosales, B Ko, JA Campos-Sandoval, ... Cancers 15 (2), 531, 2023 | 14 | 2023 |
Metabolic impact of pathogenic variants in the mitochondrial glutamyl‐tRNA synthetase EARS2 M Ni, LF Black, C Pan, H Vu, J Pei, B Ko, L Cai, A Solmonson, C Yang, ... Journal of inherited metabolic disease 44 (4), 949-960, 2021 | 11 | 2021 |
Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples F Cai, D Bezwada, L Cai, R Mahar, Z Wu, MC Chang, P Pachnis, C Yang, ... Cell metabolism 35 (10), 1830-1843. e5, 2023 | 5 | 2023 |
Electron transport chain inhibition increases cellular dependence on purine transport and salvage Z Wu, D Bezwada, F Cai, RC Harris, B Ko, V Sondhi, C Pan, HS Vu, ... Cell Metabolism, 2024 | 4 | 2024 |
Transformation of chicory with γ-TMT gene using Agrobacterium tumefaciens HJ Hwang, BK Ko, KH Baek, GW Choi Korean Journal of Horticultural Science and Technology 27 (2), 2009 | 3 | 2009 |
The hexosamine biosynthesis pathway is a targetable liability in lung cancers with concurrent KRAS and LKB1 mutations J Kim, F Cai, B Ko, C Yang, HM Lee, N Muhammad, K Li, M Haloul, W Gu, ... bioRxiv, 2020.04. 13.039669, 2020 | 1 | 2020 |
Electron transport inhibition increases cellular dependence on purine transport and salvage Z Wu, D Bezwada, RC Harris, C Pan, PT Nguyen, B Faubert, L Cai, F Cai, ... | | 2023 |
Metabolic changes upon GLS inhibition by CB-839 in glioma cell lines T Rosales, B Ko, J Márquez-Gómez, RJ Berardinis, JM Mates-Sánchez | | 2012 |
Enhanced Kinetic Analysis of Hyperpolarized Pyruvate Metabolism in Cancer Cells Identifies a Compensatory Pathway Supplied by Glutamine L Lumata, C Yang, B Ko, RJ Deberardinis, ME Merritt | | |