Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin CD Austin, AM De Mazière, PI Pisacane, SM van Dijk, C Eigenbrot, ... Molecular biology of the cell 15 (12), 5268-5282, 2004 | 560 | 2004 |
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins AA Peden, V Oorschot, BA Hesser, CD Austin, RH Scheller, ... The Journal of cell biology 164 (7), 1065-1076, 2004 | 392 | 2004 |
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma A Shikotra, DF Choy, CM Ohri, E Doran, C Butler, B Hargadon, M Shelley, ... Journal of allergy and clinical immunology 129 (1), 104-111. e9, 2012 | 352 | 2012 |
Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network YG Chen, A Siddhanta, CD Austin, SM Hammond, TC Sung, MA Frohman, ... The Journal of cell biology 138 (3), 495-504, 1997 | 343 | 1997 |
On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with … JE Fox, L Lipfert, EA Clark, CC Reynolds, CD Austin, JS Brugge Journal of Biological Chemistry 268 (34), 25973-25984, 1993 | 292 | 1993 |
Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody–drug conjugates CD Austin, X Wen, L Gazzard, C Nelson, RH Scheller, SJ Scales Proceedings of the National Academy of Sciences 102 (50), 17987-17992, 2005 | 287 | 2005 |
Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets JE Fox, CD Austin, CC Reynolds, PK Steffen Journal of Biological Chemistry 266 (20), 13289-13295, 1991 | 279 | 1991 |
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation D Seshasayee, WP Lee, M Zhou, J Shu, E Suto, J Zhang, L Diehl, ... The Journal of clinical investigation 117 (12), 3868-3878, 2007 | 252 | 2007 |
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung D Lafkas, A Shelton, C Chiu, G de Leon Boenig, Y Chen, SS Stawicki, ... Nature 528 (7580), 127-131, 2015 | 227 | 2015 |
Role of the membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane. JE Fox, CD Austin, JK Boyles, PK Steffen The Journal of cell biology 111 (2), 483-493, 1990 | 194 | 1990 |
IgE+ memory B cells and plasma cells generated through a germinal-center pathway O Talay, D Yan, HD Brightbill, EEM Straney, M Zhou, E Ladi, WP Lee, ... Nature immunology 13 (4), 396, 2012 | 185 | 2012 |
Structural basis for dual-mode inhibition of the ABC transporter MsbA H Ho, A Miu, MK Alexander, NK Garcia, A Oh, I Zilberleyb, M Reichelt, ... Nature 557 (7704), 196-201, 2018 | 147 | 2018 |
Function of CSF1 and IL34 in macrophage homeostasis, inflammation, and cancer WY Lin, D Xu, CD Austin, P Caplazi, K Senger, Y Sun, S Jeet, J Young, ... Frontiers in immunology 10, 2019, 2019 | 145 | 2019 |
Death-receptor activation halts clathrin-dependent endocytosis CD Austin, DA Lawrence, AA Peden, EE Varfolomeev, K Totpal, ... Proceedings of the National Academy of Sciences 103 (27), 10283-10288, 2006 | 134 | 2006 |
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus HD Brightbill, E Suto, N Blaquiere, N Ramamoorthi, S Sujatha-Bhaskar, ... Nature communications 9 (1), 179, 2018 | 109 | 2018 |
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ... Cell 179 (2), 417-431. e19, 2019 | 88 | 2019 |
The role of calpain in stimulus-response coupling: evidence that calpain mediates agonist-induced expression of procoagulant activity in platelets JE Fox, CC Reynolds, CD Austin | 83 | 1990 |
Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors. CD Austin, D Shields The Journal of cell biology 135 (6), 1471-1483, 1996 | 82 | 1996 |
Host-derived fatty acids activate type VII secretion in Staphylococcus aureus MS Lopez, IS Tan, D Yan, J Kang, M McCreary, Z Modrusan, CD Austin, ... Proceedings of the National Academy of Sciences 114 (42), 11223-11228, 2017 | 72 | 2017 |
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment A Balestrini, V Joseph, M Dourado, RM Reese, SD Shields, L Rougé, ... Journal of Experimental Medicine 218 (4), 2021 | 70 | 2021 |