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Edward Huttlin
Edward Huttlin
Harvard Medical School
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
A tissue-specific atlas of mouse protein phosphorylation and expression
EL Huttlin, MP Jedrychowski, JE Elias, T Goswami, R Rad, SA Beausoleil, ...
Cell 143 (7), 1174-1189, 2010
17632010
Systematic and quantitative assessment of the ubiquitin-modified proteome
W Kim, EJ Bennett, EL Huttlin, A Guo, J Li, A Possemato, ME Sowa, ...
Molecular cell 44 (2), 325-340, 2011
17542011
The BioPlex network: a systematic exploration of the human interactome
EL Huttlin, L Ting, RJ Bruckner, F Gebreab, MP Gygi, J Szpyt, S Tam, ...
Cell 162 (2), 425-440, 2015
13982015
Architecture of the human interactome defines protein communities and disease networks
EL Huttlin, RJ Bruckner, JA Paulo, JR Cannon, L Ting, K Baltier, G Colby, ...
Nature 545 (7655), 505-509, 2017
13452017
MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes
GC McAlister, DP Nusinow, MP Jedrychowski, M Wühr, EL Huttlin, ...
Analytical chemistry 86 (14), 7150-7158, 2014
11662014
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
SA Sarraf, M Raman, V Guarani-Pereira, ME Sowa, EL Huttlin, SP Gygi, ...
Nature 496 (7445), 372-376, 2013
10172013
Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses
GC McAlister, EL Huttlin, W Haas, L Ting, MP Jedrychowski, JC Rogers, ...
Analytical chemistry 84 (17), 7469-7478, 2012
6292012
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome
EL Huttlin, RJ Bruckner, J Navarrete-Perea, JR Cannon, K Baltier, ...
Cell 184 (11), 3022-3040. e28, 2021
5512021
Quantitative temporal viromics: an approach to investigate host-pathogen interaction
MP Weekes, P Tomasec, EL Huttlin, CA Fielding, D Nusinow, RJ Stanton, ...
Cell 157 (6), 1460-1472, 2014
4702014
A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides
JM Chick, D Kolippakkam, DP Nusinow, B Zhai, R Rad, EL Huttlin, ...
Nature biotechnology 33 (7), 743-749, 2015
4252015
Quantitative proteomic atlas of ubiquitination and acetylation in the DNA damage response
AEH Elia, AP Boardman, DC Wang, EL Huttlin, RA Everley, N Dephoure, ...
Molecular cell 59 (5), 867-881, 2015
3582015
Defining the consequences of genetic variation on a proteome-wide scale
JM Chick, SC Munger, P Simecek, EL Huttlin, K Choi, DM Gatti, ...
Nature 534 (7608), 500-505, 2016
3452016
TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples
J Li, JG Van Vranken, L Pontano Vaites, DK Schweppe, EL Huttlin, ...
Nature methods 17 (4), 399-404, 2020
3312020
A large-scale method to measure absolute protein phosphorylation stoichiometries
R Wu, W Haas, N Dephoure, EL Huttlin, B Zhai, ME Sowa, SP Gygi
Nature methods 8 (8), 677-683, 2011
3092011
Whole-genome expression profiling of the marine diatom Thalassiosira pseudonana identifies genes involved in silicon bioprocesses
T Mock, MP Samanta, V Iverson, C Berthiaume, M Robison, K Holtermann, ...
Proceedings of the National Academy of Sciences 105 (5), 1579-1584, 2008
3032008
Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′ TOP mRNA translation
J Tcherkezian, M Cargnello, Y Romeo, EL Huttlin, G Lavoie, SP Gygi, ...
Genes & development 28 (4), 357-371, 2014
2912014
A quantitative tissue-specific landscape of protein redox regulation during aging
H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ...
Cell 180 (5), 968-983. e24, 2020
2542020
Evaluation of HCD-and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics
MP Jedrychowski, EL Huttlin, W Haas, ME Sowa, R Rad, SP Gygi
Molecular & Cellular Proteomics 10 (12), 2011
2492011
Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes
R Wu, N Dephoure, W Haas, EL Huttlin, B Zhai, ME Sowa, SP Gygi
Molecular & cellular proteomics 10 (8), 2011
1932011
Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics
DK Schweppe, JK Eng, Q Yu, D Bailey, R Rad, J Navarrete-Perea, ...
Journal of proteome research 19 (5), 2026-2034, 2020
1892020
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