Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands CD Hodneland, YS Lee, DH Min, M Mrksich Proceedings of the National Academy of Sciences 99 (8), 5048-5052, 2002 | 453 | 2002 |
Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates YS Lee, S Mulugu, JD York, EK O'Shea Science 316 (5821), 109, 2007 | 330 | 2007 |
SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions KE Keller, IS Tan, YS Lee Science 338 (6110), 1069, 2012 | 247 | 2012 |
Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate YS Lee, K Huang, FA Quiocho, EK O'Shea Nature chemical biology 4 (1), 25-32, 2008 | 180 | 2008 |
Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin Q Guo, Y Shen, YS Lee, CS Gibbs, M Mrksich, WJ Tang The EMBO journal 24 (18), 3190-3201, 2005 | 172 | 2005 |
SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells KE Keller, ZM Doctor, ZW Dwyer, YS Lee Molecular Cell 53 (5), 700-709, 2014 | 166 | 2014 |
Protein chips: from concept to practice YS Lee, M Mrksich Trends in biotechnology 20 (12), s14-s18, 2002 | 157 | 2002 |
Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins Y Shen, YS Lee, S Soelaiman, P Bergson, D Lu, A Chen, K Beckingham, ... The EMBO journal 21 (24), 6721-6732, 2002 | 116 | 2002 |
Structure-based inhibitor discovery against adenylyl cyclase toxins from pathogenic bacteria that cause anthrax and whooping cough S Soelaiman, BQ Wei, P Bergson, YS Lee, Y Shen, M Mrksich, ... Journal of Biological Chemistry 278 (28), 25990-25997, 2003 | 110 | 2003 |
Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function J Kim, H Xiao, JB Bonanno, C Kalyanaraman, S Brown, X Tang, ... Nature 498 (7452), 123-126, 2013 | 93 | 2013 |
Discovery of a small molecule that inhibits the interaction of anthrax edema factor with its cellular activator, calmodulin YS Lee, P Bergson, WS He, M Mrksich, WJ Tang Chemistry & biology 11 (8), 1139-1146, 2004 | 46 | 2004 |
SAICAR activates PKM2 in its dimeric form M Yan, S Chakravarthy, JM Tokuda, L Pollack, GD Bowman, YS Lee Biochemistry, 2016 | 34* | 2016 |
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification J Kim, H Xiao, J Koh, Y Wang, JB Bonanno, K Thomas, PC Babbitt, ... Nucleic acids research 43 (9), 4602-4613, 2015 | 26 | 2015 |
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites JH Lee, EP Mosher, YS Lee, NN Bumpus, JM Berger Cell Chemical Biology, doi: 10.1016/j.chembiol.2021.08.014, 2021 | 11 | 2021 |
Activation and stabilization of chymotrypsin in microdomains of poly (ethylenimine) derivatives. A model of in vivo environment J Suh, Y Lee, S Han Bioorganic & medicinal chemistry letters 8 (11), 1331-1336, 1998 | 11 | 1998 |
N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia JS Park, AM Gabel, P Kassir, L Kang, PK Chowdhary, A Osei-Ntansah, ... eLife 11, e74031, 2022 | 3 | 2022 |
Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development B Connor, K Titialii-Torres, AE Rockenhaus, S Passamonte, AC Morris, ... Scientific Reports 12 (1), 7310, 2022 | 2 | 2022 |
Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of 13C-Bicarbonate Incorporation H Shon, EA Matveeva, EC Jull, Y Hu, TA Coupet, YS Lee Biochemistry, 2022 | 2 | 2022 |
Endogenous Ligand for Orphan Nuclear Receptor NR2E3 Forms a Light‐Sensitive Retinal Transcription System B Connor, YS Lee The FASEB Journal 31, 616.5-616.5, 2017 | 1 | 2017 |
Synthesis of biological activity of 3-and 5-PP-IP5 J Zhang, H Zhang, YS Lee, E O'Shea, GD Prestwich ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 237, 474-474, 2009 | | 2009 |