| The nuclear pore complex: bridging nuclear transport and gene regulation C Strambio-De-Castillia, M Niepel, MP Rout Nature reviews Molecular cell biology 11 (7), 490-501, 2010 | 649 | 2010 |
| Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs M Hafner, M Niepel, M Chung, PK Sorger Nature methods 13 (6), 521-527, 2016 | 585 | 2016 |
| Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data WW Chen, B Schoeberl, PJ Jasper, M Niepel, UB Nielsen, ... Molecular systems biology 5 (1), 239, 2009 | 473 | 2009 |
| The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 390 | 2018 |
| Classic and contemporary approaches to modeling biochemical reactions WW Chen, M Niepel, PK Sorger Genes & development 24 (17), 1861-1875, 2010 | 387 | 2010 |
| Discovery of potent and selective covalent inhibitors of JNK T Zhang, F Inesta-Vaquera, M Niepel, J Zhang, SB Ficarro, T Machleidt, ... Chemistry & biology 19 (1), 140-154, 2012 | 353 | 2012 |
| LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures Q Duan, C Flynn, M Niepel, M Hafner, JL Muhlich, NF Fernandez, ... Nucleic acids research 42 (W1), W449-W460, 2014 | 326 | 2014 |
| L1000CDS2: LINCS L1000 characteristic direction signatures search engine Q Duan, SP Reid, NR Clark, Z Wang, NF Fernandez, AD Rouillard, ... NPJ systems biology and applications 2 (1), 1-12, 2016 | 270 | 2016 |
| Non-genetic cell-to-cell variability and the consequences for pharmacology M Niepel, SL Spencer, PK Sorger Current opinion in chemical biology 13 (5-6), 556-561, 2009 | 255 | 2009 |
| Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR Q Liu, C Xu, S Kirubakaran, X Zhang, W Hur, Y Liu, NP Kwiatkowski, ... Cancer research 73 (8), 2574-2586, 2013 | 228 | 2013 |
| Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE) EO Paull, DE Carlin, M Niepel, PK Sorger, D Haussler, JM Stuart Bioinformatics 29 (21), 2757-2764, 2013 | 203 | 2013 |
| ADP‐ribosyltransferases, an update on function and nomenclature B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ... The FEBS journal 289 (23), 7399-7410, 2022 | 178 | 2022 |
| Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway T Shi, M Niepel, JE McDermott, Y Gao, CD Nicora, WB Chrisler, ... Science Signaling 9 (436), rs6-rs6, 2016 | 137 | 2016 |
| Identification and characterization of the functional elements within the tobacco etch virus 5′ leader required for cap-independent translation M Niepel, DR Gallie Journal of virology 73 (11), 9080-9088, 1999 | 134 | 1999 |
| Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics Q Liu, S Kirubakaran, W Hur, M Niepel, K Westover, CC Thoreen, J Wang, ... Journal of Biological Chemistry 287 (13), 9742-9752, 2012 | 129 | 2012 |
| A multi-center study on the reproducibility of drug-response assays in mammalian cell lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell systems 9 (1), 35-48. e5, 2019 | 124 | 2019 |
| A cell cycle phosphoproteome of the yeast centrosome JM Keck, MH Jones, CCL Wong, J Binkley, D Chen, SL Jaspersen, ... Science 332 (6037), 1557, 2011 | 120 | 2011 |
| The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome M Niepel, KR Molloy, R Williams, JC Farr, AC Meinema, N Vecchietti, ... Molecular Biology of the Cell, mbc. E13-07-0412, 2013 | 119 | 2013 |
| Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines M Niepel, M Hafner, EA Pace, M Chung, DH Chai, L Zhou, B Schoeberl, ... Science signaling 6 (294), ra84-ra84, 2013 | 108 | 2013 |
| Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c‐Jun pathway in adaptive resistance to drug‐induced apoptosis M Fallahi‐Sichani, NJ Moerke, M Niepel, T Zhang, NS Gray, PK Sorger Molecular systems biology 11 (3), 797, 2015 | 107 | 2015 |
Peter K. SorgerHarvard Medical SchoolVerified email at hms.harvard.edu
