Andy Yip
Andy Yip
Novartis Institute for Tropical Diseases
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An adenosine nucleoside inhibitor of dengue virus
Z Yin, YL Chen, W Schul, QY Wang, F Gu, J Duraiswamy, RR Kondreddi, ...
Proceedings of the National Academy of Sciences 106 (48), 20435-20439, 2009
The structural basis for serotype-specific neutralization of dengue virus by a human antibody
EP Teoh, P Kukkaro, EW Teo, APC Lim, TT Tan, A Yip, W Schul, M Aung, ...
Science translational medicine 4 (139), 139ra83-139ra83, 2012
A small molecule fusion inhibitor of dengue virus
MK Poh, A Yip, S Zhang, JP Priestle, NL Ma, JM Smit, J Wilschut, PY Shi, ...
Antiviral research 84 (3), 260-266, 2009
A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis
D Grant, GK Tan, M Qing, JKW Ng, A Yip, G Zou, X Xie, Z Yuan, ...
Journal of virology 85 (15), 7775-7787, 2011
Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo
J Chang, W Schul, TD Butters, A Yip, B Liu, A Goh, SB Lakshminarayana, ...
Antiviral research 89 (1), 26-34, 2011
NMR analysis of a novel enzymatically active unlinked dengue NS2B-NS3 protease complex
YM Kim, S Gayen, CB Kang, J Joy, Q Huang, AS Chen, JLK Wee, ...
Journal of Biological Chemistry 288 (18), 12891-12900, 2013
Inhibition of dengue virus RNA synthesis by an adenosine nucleoside
YL Chen, Z Yin, J Duraiswamy, W Schul, CC Lim, B Liu, HY Xu, M Qing, ...
Antimicrobial agents and chemotherapy 54 (7), 2932-2939, 2010
Periodic re-emergence of endemic strains with strong epidemic potential-a proposed explanation for the 2004 Indonesian dengue epidemic
SMJ Ong SH, Yip JT, Chen YL, Liu W, Harun S, Lystiyaningsih E, Heriyanto B ...
Infect. Genet. Evol. 8 (2), 191-204, 2008
Competitive inhibitor of cellular α-glucosidases protects mice from lethal dengue virus infection
J Chang, W Schul, A Yip, X Xu, JT Guo, TM Block
Antiviral research 92 (2), 369-371, 2011
Inhibition of dengue virus by an ester prodrug of an adenosine analog
YL Chen, Z Yin, SB Lakshminarayana, M Qing, W Schul, J Duraiswamy, ...
Antimicrobial agents and chemotherapy 54 (8), 3255-3261, 2010
Lead optimization of spiropyrazolopyridones: a new and potent class of dengue virus inhibitors
B Zou, WL Chan, M Ding, SY Leong, S Nilar, PG Seah, W Liu, R Karuna, ...
ACS medicinal chemistry letters 6 (3), 344-348, 2015
Modulation of inflammation and pathology during dengue virus infection by p38 MAPK inhibitor SB203580
Y Fu, A Yip, PG Seah, F Blasco, PY Shi, M Hervé
Antiviral research 110, 151-157, 2014
A genomics approach to understanding host response during dengue infection
ML Hibberd, L Ling, T Tolfvenstam, W Mitchell, C Wong, VA Kuznetsov, ...
Novartis Foundation symposium 277, 206, 2006
Testing antiviral compounds in a dengue mouse model
W Schul, A Yip, PY Shi
Antiviral Methods and Protocols, 269-281, 2013
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