Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis RW Neumar, YA Xu, H Gada, RP Guttmann, R Siman Journal of Biological Chemistry 278 (16), 14162-14167, 2003 | 323 | 2003 |
Excitotoxicity: perspectives based onN-methyl-D-aspartate receptor subtypes DR Lynch, RP Guttmann Journal of Pharmacology and Experimental Therapeutics 300 (3), 717-723, 2002 | 295 | 2002 |
Modulation of the in situ activity of tissue transglutaminase by calcium and GTP J Zhang, M Lesort, RP Guttmann, GVW Johnson Journal of Biological Chemistry 273 (4), 2288-2295, 1998 | 241 | 1998 |
NMDA receptor pharmacology: perspectives from molecular biology DR Lynch, RP Guttmann Current drug targets 2 (3), 215-231, 2001 | 185 | 2001 |
Distinct cleavage patterns of normal and pathologic forms of α‐synuclein by calpain I in vitro AJ Mishizen‐Eberz, RP Guttmann, BI Giasson, GA Day III, R Hodara, ... Journal of neurochemistry 86 (4), 836-847, 2003 | 182 | 2003 |
Selective activation induced cleavage of the NR2B subunit by calpain KL Simpkins, RP Guttmann, Y Dong, Z Chen, S Sokol, RW Neumar, ... Journal of Neuroscience 23 (36), 11322-11331, 2003 | 181 | 2003 |
Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation R Yadavalli, RP Guttmann, T Seward, AP Centers, RA Williamson, ... Journal of Biological Chemistry 279 (21), 21948-21956, 2004 | 153 | 2004 |
Specific proteolysis of the NR2 subunit at multiple sites by calpain RP Guttmann, DL Baker, KM Seifert, AS Cohen, DA Coulter, DR Lynch Journal of neurochemistry 78 (5), 1083-1093, 2001 | 138 | 2001 |
Calpains: intact and active? GVW Johnson, RP Guttmann Bioessays 19 (11), 1011-1018, 1997 | 132 | 1997 |
'Oxidation inhibits substrate proteolysis by calpain I but not autolysis RP Guttmann, JS Elce, PD Bell, JC Isbell, GVW Johnson Journal of Biological Chemistry 272 (3), 2005-2012, 1997 | 125 | 1997 |
Oxidative stress inhibits calpain activity in situ RP Guttmann, GVW Johnson Journal of Biological Chemistry 273 (21), 13331-13338, 1998 | 117 | 1998 |
Proteolysis of theN-Methyl-d-aspartate receptor by calpain in situ RP Guttmann, S Sokol, DL Baker, KL Simpkins, Y Dong, DR Lynch Journal of Pharmacology and Experimental Therapeutics 302 (3), 1023-1030, 2002 | 103 | 2002 |
Frataxin point mutations in two patients with Friedreich's ataxia and unusual clinical features ML McCormack, RP Guttmann, M Schumann, JM Farmer, CA Stolle, ... Journal of Neurology, Neurosurgery & Psychiatry 68 (5), 661-664, 2000 | 73 | 2000 |
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture H Mohmmad Abdul, I Baig, H LeVine 3rd, RP Guttmann, CM Norris Aging cell 10 (1), 103-113, 2011 | 55 | 2011 |
Pharmacological characterization of interactions of RO 25-6981 with the NR2B (ε2) subunit DR Lynch, SS Shim, KM Seifert, S Kurapathi, V Mutel, MJ Gallagher, ... European journal of pharmacology 416 (3), 185-195, 2001 | 52 | 2001 |
Tissue transglutaminase is an in situ substrate of calpain: regulation of activity J Zhang, RP Guttmann, GVW Johnson Journal of neurochemistry 71 (1), 240-247, 1998 | 49 | 1998 |
τ Self‐Association: Stabilization with a Chemical Cross‐Linker and Modulation by Phosphorylation and Oxidation State RP Guttmann, AC Erickson, GVW Johnson Journal of neurochemistry 64 (3), 1209-1215, 1995 | 48 | 1995 |
N-Methyl-D-aspartate receptor mediated toxicity in nonneuronal cell lines: characterization using fluorescent measures of cell viability and reactive oxygen species production NJ Anegawa, RP Guttmann, ER Grant, R Anand, J Lindstrom, DR Lynch Molecular brain research 77 (2), 163-175, 2000 | 45 | 2000 |
Calcineurin proteolysis in astrocytes: implications for impaired synaptic function MM Pleiss, P Sompol, SD Kraner, HM Abdul, JL Furman, RP Guttmann, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (9 …, 2016 | 42 | 2016 |
Identification and characterization of PEBP as a calpain substrate Q Chen, S Wang, SN Thompson, ED Hall, RP Guttmann Journal of neurochemistry 99 (4), 1133-1141, 2006 | 40 | 2006 |