| A faux 3′-UTR promotes aberrant termination and triggers nonsense- mediated mRNA decay N Amrani, R Ganesan, S Kervestin, DA Mangus, S Ghosh, A Jacobson Nature 432 (7013), 112-118, 2004 | 640 | 2004 |
| Naturally occurring off-switches for CRISPR-Cas9 A Pawluk, N Amrani, Y Zhang, B Garcia, Y Hidalgo-Reyes, J Lee, A Edraki, ... Cell 167 (7), 1829-1838. e9, 2016 | 423 | 2016 |
| Early nonsense: mRNA decay solves a translational problem N Amrani, MS Sachs, A Jacobson Nature reviews Molecular cell biology 7 (6), 415-425, 2006 | 343 | 2006 |
| A broad-spectrum inhibitor of CRISPR-Cas9 LB Harrington, KW Doxzen, E Ma, JJ Liu, GJ Knott, A Edraki, B Garcia, ... Cell 170 (6), 1224-1233. e15, 2017 | 274 | 2017 |
| Pbp1p, a Factor Interacting withSaccharomyces cerevisiae Poly(A)-Binding Protein, Regulates Polyadenylation DA Mangus, N Amrani, A Jacobson Molecular and cellular biology 18 (12), 7383-7396, 1998 | 246 | 1998 |
| Translation factors promote the formation of two states of the closed-loop mRNP N Amrani, S Ghosh, DA Mangus, A Jacobson Nature 453 (7199), 1276-1280, 2008 | 238 | 2008 |
| Yeast Pab1 interacts with Rna15 and participates in the control of the poly (A) tail length in vitro N Amrani, M Minet, M Le Gouar, F Lacroute, F Wyers Molecular and cellular biology, 1997 | 177 | 1997 |
| NmeCas9 is an intrinsically high-fidelity genome-editing platform N Amrani, XD Gao, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, KE Sasaki, ... Genome Biology 19, 1-25, 2018 | 130 | 2018 |
| PCF11 Encodes a Third Protein Component of Yeast Cleavage and Polyadenylation Factor I N Amrani, M Minet, F Wyers, ME Dufour, LP Aggerbeck, F Lacroute Molecular and cellular biology 17 (3), 1102-1109, 1997 | 120 | 1997 |
| An engineered ScCas9 with broad PAM range and high specificity and activity P Chatterjee, N Jakimo, J Lee, N Amrani, T Rodríguez, SRT Koseki, ... Nature Biotechnology 38 (10), 1154-1158, 2020 | 116 | 2020 |
| All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo R Ibraheim, CQ Song, A Mir, N Amrani, W Xue, EJ Sontheimer Genome biology 19, 1-11, 2018 | 108 | 2018 |
| Aberrant termination triggers nonsense-mediated mRNA decay N Amrani, S Dong, F He, R Ganesan, S Ghosh, S Kervestin, C Li, ... Biochemical Society Transactions 34 (1), 39-42, 2006 | 107 | 2006 |
| Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 anti-CRISPR proteins J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ... MBio 9 (6), 10.1128/mbio. 02321-18, 2018 | 91 | 2018 |
| Structures of Neisseria meningitidis Cas9 complexes in catalytically poised and anti-CRISPR-inhibited states W Sun, J Yang, Z Cheng, N Amrani, C Liu, K Wang, R Ibraheim, A Edraki, ... Molecular cell 76 (6), 938-952. e5, 2019 | 83 | 2019 |
| Toeprint analysis of the positioning of translation apparatus components at initiation and termination codons of fungal mRNAs MS Sachs, Z Wang, A Gaba, P Fang, J Belk, R Ganesan, N Amrani, ... Methods 26 (2), 105-114, 2002 | 80 | 2002 |
| Genetic variability for haploid production in crosses between tetraploid and hexaploid wheats with maize N Amrani, A Sarrafi, G Alibert Plant Breeding 110 (2), 123-128, 1993 | 61 | 1993 |
| Translational competence of ribosomes released from a premature termination codon is modulated by NMD factors S Ghosh, R Ganesan, N Amrani, A Jacobson Rna 16 (9), 1832-1847, 2010 | 56 | 2010 |
| The use of fungal in vitro systems for studying translational regulation C Wu, N Amrani, A Jacobson, MS Sachs Methods in enzymology 429, 203-225, 2007 | 48 | 2007 |
| Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit EE Min, B Roy, N Amrani, F He, A Jacobson Rna 19 (8), 1105-1115, 2013 | 46 | 2013 |
| CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease E Tsagkaraki, SM Nicoloro, T DeSouza, J Solivan-Rivera, A Desai, ... Nature Communications 12 (1), 6931, 2021 | 44 | 2021 |
Erik SontheimerRNA Therapeutics Institute, UMass Medical SchoolVerified email at umassmed.edu
