Tim Forshew
Tim Forshew
Inivata - co-founder
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Analysis of circulating tumor DNA to monitor metastatic breast cancer
SJ Dawson, DWY Tsui, M Murtaza, H Biggs, OM Rueda, SF Chin, ...
New England Journal of Medicine 368 (13), 1199-1209, 2013
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
M Murtaza, SJ Dawson, DWY Tsui, D Gale, T Forshew, AM Piskorz, ...
Nature 497 (7447), 108-112, 2013
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA
T Forshew, M Murtaza, C Parkinson, D Gale, DWY Tsui, F Kaper, ...
Science translational medicine 4 (136), 136ra68-136ra68, 2012
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer
T Cooks, IS Pateras, O Tarcic, H Solomon, AJ Schetter, S Wilder, ...
Cancer cell 23 (5), 634-646, 2013
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
JMJ Weaver, CS Ross-Innes, N Shannon, AG Lynch, T Forshew, ...
Nature genetics 46 (8), 837-843, 2014
Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome
P Gissen, CA Johnson, NV Morgan, JM Stapelbroek, T Forshew, ...
Nature genetics 36 (4), 400-404, 2004
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
T Cooks, IS Pateras, LM Jenkins, KM Patel, AI Robles, J Morris, ...
Nature communications 9 (1), 771, 2018
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas
T Forshew, RG Tatevossian, ARJ Lawson, J Ma, G Neale, ...
The Journal of pathology 218 (2), 172-181, 2009
Targeted Therapy for BRAFV600E Malignant AstrocytomaTargeting BRAFV600E in Malignant Astrocytoma
TP Nicolaides, H Li, DA Solomon, S Hariono, R Hashizume, K Barkovich, ...
Clinical Cancer Research 17 (24), 7595-7604, 2011
Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma
L Gossage, M Murtaza, AF Slatter, CP Lichtenstein, A Warren, B Haynes, ...
Genes, Chromosomes and Cancer 53 (1), 38-51, 2014
Mapping of a novel locus for achromatopsia (ACHM4) to 1p and identification of a germline mutation in the α subunit of cone transducin (GNAT2)
IA Aligianis, T Forshew, S Johnson, M Michaelides, CA Johnson, ...
Journal of medical genetics 39 (9), 656, 2002
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells
M Vinci, A Burford, V Molinari, K Kessler, S Popov, M Clarke, KR Taylor, ...
Nature medicine 24 (8), 1204-1215, 2018
Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA
D Gale, ARJ Lawson, K Howarth, M Madi, B Durham, S Smalley, ...
PloS one 13 (3), e0194630, 2018
MAPK pathway activation and the origins of pediatric low‐grade astrocytomas
RG Tatevossian, ARJ Lawson, T Forshew, GFL Hindley, DW Ellison, ...
Journal of cellular physiology 222 (3), 509-514, 2010
Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling
V Plagnol, S Woodhouse, K Howarth, S Lensing, M Smith, M Epstein, ...
PloS one 13 (3), e0193802, 2018
Locus heterogeneity in autosomal recessive congenital cataracts: linkage to 9q and germline HSF4 mutations
T Forshew, CA Johnson, S Khaliq, S Pasha, C Willis, R Abbasi, L Tee, ...
Human genetics 117, 452-459, 2005
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas
RG Tatevossian, B Tang, J Dalton, T Forshew, AR Lawson, J Ma, G Neale, ...
Acta neuropathologica 120, 731-743, 2010
Association of plasma and urinary mutant DNA with clinical outcomes in muscle invasive bladder cancer
KM Patel, KE Van Der Vos, CG Smith, F Mouliere, D Tsui, J Morris, ...
Scientific Reports 7 (1), 5554, 2017
MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma
S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ...
Development 144 (12), 2141-2152, 2017
RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology
ARJ Lawson, GFL Hindley, T Forshew, RG Tatevossian, GA Jamie, ...
Genome research 21 (4), 505-514, 2011
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