Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ... Biochemistry 52 (19), 3376-3389, 2013 | 121 | 2013 |
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass … P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ... Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013 | 102 | 2013 |
Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies R Majumdar, CR Middaugh, DD Weis, DB Volkin Journal of pharmaceutical sciences 104 (2), 327-345, 2015 | 80 | 2015 |
Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ... Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012 | 77 | 2012 |
Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody J Arora, JM Hickey, R Majumdar, R Esfandiary, SM Bishop, HS Samra, ... MAbs 7 (3), 525-539, 2015 | 75 | 2015 |
Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life R Majumdar, R Esfandiary, SM Bishop, HS Samra, CR Middaugh, ... MAbs 7 (1), 84-95, 2015 | 69 | 2015 |
Physical characterization of polyethylene glycols by thermal analytical technique and the effect of humidity and molecular weight R Majumdar, KS Alexander, AT Riga Die Pharmazie-An International Journal of Pharmaceutical Sciences 65 (5 …, 2010 | 38 | 2010 |
High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation MA Alsenaidy, JH Kim, R Majumdar, DD Weis, SB Joshi, TJ Tolbert, ... Journal of pharmaceutical sciences 102 (11), 3942-3956, 2013 | 36 | 2013 |
Understanding the increased aggregation propensity of a light-exposed IgG1 monoclonal antibody using hydrogen exchange mass spectrometry, biophysical characterization, and … R Bommana, Q Chai, C Schöneich, WF Weiss IV, R Majumdar Journal of pharmaceutical sciences 107 (6), 1498-1511, 2018 | 29 | 2018 |
Best practices for aggregate quantitation of antibody therapeutics by sedimentation velocity analytical ultracentrifugation GM Bou-Assaf, IL Budyak, M Brenowitz, ES Day, D Hayes, J Hill, ... Journal of pharmaceutical sciences 111 (7), 2121-2133, 2022 | 9 | 2022 |
Subclass Effects on Self-Association and Viscosity of Monoclonal Antibodies at High Concentrations AA Chowdhury, N Manohar, MA Witek, MA Woldeyes, R Majumdar, ... Molecular Pharmaceutics 20 (6), 2991-3008, 2023 | 7 | 2023 |
Hydrogen Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies R Majumdar, CR Middaugh, DD Weis, DB Volkin Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods, and …, 2016 | 2 | 2016 |
Characterizing Protein–Protein Interactions and Viscosity of a Monoclonal Antibody from Low to High Concentration Using Small-Angle X-ray Scattering and Molecular Dynamics … AA Chowdhury, N Manohar, A Lanzaro, WD Kimball, MA Witek, ... Molecular Pharmaceutics 20 (11), 5563-5578, 2023 | 1 | 2023 |
UNDERSTANDING THE RELATIONSHIPS BETWEEN LOCAL DYNAMICS AND PHYSICAL STABILITY OF IgG1 ANTIBODIES: EFFECTS OF EXCIPIENTS, SALTS AND MUTATIONS R Majumdar University of Kansas, 2014 | | 2014 |
Development of Solid Dispersions to Improve Formulation Characteristics and Dissolution of API's: Ibuprofen and Furosemide R Majumdar University of Toledo, 2009 | | 2009 |