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Ranajoy Majumdar
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Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ...
Biochemistry 52 (19), 3376-3389, 2013
1212013
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass …
P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ...
Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013
1022013
Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies
R Majumdar, CR Middaugh, DD Weis, DB Volkin
Journal of pharmaceutical sciences 104 (2), 327-345, 2015
802015
Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ...
Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012
772012
Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody
J Arora, JM Hickey, R Majumdar, R Esfandiary, SM Bishop, HS Samra, ...
MAbs 7 (3), 525-539, 2015
752015
Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life
R Majumdar, R Esfandiary, SM Bishop, HS Samra, CR Middaugh, ...
MAbs 7 (1), 84-95, 2015
692015
Physical characterization of polyethylene glycols by thermal analytical technique and the effect of humidity and molecular weight
R Majumdar, KS Alexander, AT Riga
Die Pharmazie-An International Journal of Pharmaceutical Sciences 65 (5 …, 2010
382010
High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation
MA Alsenaidy, JH Kim, R Majumdar, DD Weis, SB Joshi, TJ Tolbert, ...
Journal of pharmaceutical sciences 102 (11), 3942-3956, 2013
362013
Understanding the increased aggregation propensity of a light-exposed IgG1 monoclonal antibody using hydrogen exchange mass spectrometry, biophysical characterization, and …
R Bommana, Q Chai, C Schöneich, WF Weiss IV, R Majumdar
Journal of pharmaceutical sciences 107 (6), 1498-1511, 2018
292018
Best practices for aggregate quantitation of antibody therapeutics by sedimentation velocity analytical ultracentrifugation
GM Bou-Assaf, IL Budyak, M Brenowitz, ES Day, D Hayes, J Hill, ...
Journal of pharmaceutical sciences 111 (7), 2121-2133, 2022
92022
Subclass Effects on Self-Association and Viscosity of Monoclonal Antibodies at High Concentrations
AA Chowdhury, N Manohar, MA Witek, MA Woldeyes, R Majumdar, ...
Molecular Pharmaceutics 20 (6), 2991-3008, 2023
72023
Hydrogen Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies
R Majumdar, CR Middaugh, DD Weis, DB Volkin
Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods, and …, 2016
22016
Characterizing Protein–Protein Interactions and Viscosity of a Monoclonal Antibody from Low to High Concentration Using Small-Angle X-ray Scattering and Molecular Dynamics …
AA Chowdhury, N Manohar, A Lanzaro, WD Kimball, MA Witek, ...
Molecular Pharmaceutics 20 (11), 5563-5578, 2023
12023
UNDERSTANDING THE RELATIONSHIPS BETWEEN LOCAL DYNAMICS AND PHYSICAL STABILITY OF IgG1 ANTIBODIES: EFFECTS OF EXCIPIENTS, SALTS AND MUTATIONS
R Majumdar
University of Kansas, 2014
2014
Development of Solid Dispersions to Improve Formulation Characteristics and Dissolution of API's: Ibuprofen and Furosemide
R Majumdar
University of Toledo, 2009
2009
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