Sphingosine-1-phosphate receptor therapies: advances in clinical trials for CNS-related diseases S O'Sullivan, KK Dev Neuropharmacology 113, 597-607, 2017 | 105 | 2017 |
Sphingosine 1‐phosphate receptors regulate TLR 4‐induced CXCL 5 release from astrocytes and microglia SA O'Sullivan, C O'Sullivan, LM Healy, KK Dev, GK Sheridan Journal of neurochemistry 144 (6), 736-747, 2018 | 72 | 2018 |
Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes SA O’Sullivan, F Gasparini, AK Mir, KK Dev Journal of Neuroinflammation 13, 1-13, 2016 | 45 | 2016 |
Demyelination induced by oxidative stress is regulated by sphingosine 1‐phosphate receptors SA O'Sullivan, M Velasco‐Estevez, KK Dev Glia 65 (7), 1119-1136, 2017 | 42 | 2017 |
The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages A Rutkowska, SA O’Sullivan, I Christen, J Zhang, AW Sailer, KK Dev Scientific reports 6 (1), 25520, 2016 | 29 | 2016 |
Fingolimod rescues demyelination in a mouse model of Krabbe's disease S Béchet, SA O'Sullivan, J Yssel, SG Fagan, KK Dev Journal of Neuroscience 40 (15), 3104-3118, 2020 | 25 | 2020 |
Phospholipase A2 is involved in galactosylsphingosine-induced astrocyte toxicity, neuronal damage and demyelination C Misslin, M Velasco-Estevez, M Albert, SA O’Sullivan, KK Dev PLoS One 12 (11), e0187217, 2017 | 23 | 2017 |
Neuronal hyperactivity–induced oxidant stress promotes in vivo α-synuclein brain spreading M Helwig, A Ulusoy, A Rollar, SA O’Sullivan, SSL Lee, H Aboutalebi, ... Science advances 8 (35), eabn0356, 2022 | 12 | 2022 |
The chemokine fractalkine (CX3CL1) attenuates H2O2-induced demyelination in cerebellar slices SA O’Sullivan, KK Dev Journal of neuroinflammation 14, 1-9, 2017 | 12 | 2017 |
Sphingosine-1-phosphate receptor therapies: advances in clinical trials for CNS-related diseases. Neuropharmacology 113 (Pt B): 597–607 S O’Sullivan, KK Dev | 6 | 2017 |
Neuronal hyperactivity–induced oxidant stress promotes in vivo-synuclein brain spreading M Helwig, A Ulusoy, A Rollar, SA O’Sullivan, SSL Lee, H Aboutalebi, ... | 1 | 2022 |
The molecular mechanisms and potential drug targets for remyelination and neuroregeneration A Rutkowska, M Velasco-Estevez, SA O'Sullivan Frontiers in Molecular Neuroscience, 2023 | | 2023 |
Mouse perfusions and brain tissue processing A Ulusoy, S Lee, A Rollar, M Helwig, M Klinkenberg, S O'Sullivan, ... | | 2023 |
Fluorescence intensity analyses A Ulusoy, S O'Sullivan, M Helwig, A Rollar, S Lee, M Klinkenberg, ... | | 2023 |
Intravagal AAV injection in mice A Ulusoy, M Helwig, A Rollar, M Klinkenberg, S O'Sullivan, S Lee, ... | | 2023 |
Role of ectosomes in establishing the modular organization of the myelinated axon: structural findings S Szuchet, S O'Sullivan, M Domowicz JOURNAL OF NEUROCHEMISTRY 150, 243-243, 2019 | | 2019 |
Protective role of fractalkine and S1P receptors in oxidative stress induced demyelination SA O'Sullivan, KK Dev GLIA 67, E439-E440, 2019 | | 2019 |
Targeting the sphingosine 1-phosphate axis leads to phenotypic improvements and reduced neuropathology in a murine model of Krabbe's disease. S Bechet, SG Fagan, S O'Sullivan, KK Dev GLIA 67, E221-E221, 2019 | | 2019 |
In vitro models of oxidative stress induced demyelination SA O'Sullivan, KK Dev IRISH JOURNAL OF MEDICAL SCIENCE 186, S286-S286, 2017 | | 2017 |
The effects of S1P receptor modulation in an animal model of Krabbes disease S Fagan, S Bechet, J Yssel, S O'Sullivan, K Dev GLIA 65, E186-E186, 2017 | | 2017 |