| Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome RJ Perry, L Peng, NA Barry, GW Cline, D Zhang, RL Cardone, ... Nature 534 (7606), 213-217, 2016 | 1259 | 2016 |
| The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes RJ Perry, VT Samuel, KF Petersen, GI Shulman Nature 510 (7503), 84-91, 2014 | 1183 | 2014 |
| Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ... Cell 160 (4), 745-758, 2015 | 702 | 2015 |
| Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats RJ Perry, D Zhang, XM Zhang, JL Boyer, GI Shulman Science 347 (6227), 1253-1256, 2015 | 291 | 2015 |
| Regulation of adipose tissue inflammation by interleukin 6 MS Han, A White, RJ Perry, JP Camporez, J Hidalgo, GI Shulman, ... Proceedings of the National Academy of Sciences 117 (6), 2751-2760, 2020 | 271 | 2020 |
| Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo AK Madiraju, Y Qiu, RJ Perry, Y Rahimi, XM Zhang, D Zhang, ... Nature medicine 24 (9), 1384-1394, 2018 | 253 | 2018 |
| Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler RJ Perry, T Kim, XM Zhang, HY Lee, D Pesta, VB Popov, D Zhang, ... Cell metabolism 18 (5), 740-748, 2013 | 241 | 2013 |
| Origin and function of stress-induced IL-6 in murine models H Qing, R Desrouleaux, K Israni-Winger, YS Mineur, N Fogelman, ... Cell 182 (2), 372-387. e14, 2020 | 215 | 2020 |
| Acetyl‐C o A Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents L Goedeke, J Bates, DF Vatner, RJ Perry, T Wang, R Ramirez, L Li, ... Hepatology 68 (6), 2197-2211, 2018 | 209 | 2018 |
| Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis RJ Perry, XM Zhang, D Zhang, N Kumashiro, JPG Camporez, GW Cline, ... Nature medicine 20 (7), 759-763, 2014 | 209 | 2014 |
| Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates type 2 diabetes K Sharabi, H Lin, CDJ Tavares, JE Dominy, JP Camporez, RJ Perry, ... Cell 169 (1), 148-160. e15, 2017 | 175 | 2017 |
| Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism HA Ferris, RJ Perry, GV Moreira, GI Shulman, JD Horton, CR Kahn Proceedings of the National Academy of Sciences 114 (5), 1189-1194, 2017 | 174 | 2017 |
| N-acylphosphatidylethanolamine, a gut-derived circulating factor induced by fat ingestion, inhibits food intake MP Gillum, D Zhang, XM Zhang, DM Erion, RA Jamison, C Choi, J Dong, ... Cell 135 (5), 813-824, 2008 | 168 | 2008 |
| Adolescent obesity and insulin resistance: roles of ectopic fat accumulation and adipose inflammation S Caprio, R Perry, R Kursawe Gastroenterology 152 (7), 1638-1646, 2017 | 150 | 2017 |
| Leptin mediates a glucose-fatty acid cycle to maintain glucose homeostasis in starvation RJ Perry, Y Wang, GW Cline, A Rabin-Court, JD Song, S Dufour, ... Cell 172 (1-2), 234-248. e17, 2018 | 138 | 2018 |
| Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, ... Cell reports 21 (4), 1021-1035, 2017 | 134 | 2017 |
| Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans N Gómez-Banoy, JS Guseh, G Li, A Rubio-Navarro, T Chen, BA Poirier, ... Nature medicine 25 (11), 1739-1747, 2019 | 127 | 2019 |
| Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis RJ Perry, D Zhang, MT Guerra, AL Brill, L Goedeke, AR Nasiri, ... Nature 579 (7798), 279-283, 2020 | 123 | 2020 |
| FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis RJ Perry, S Lee, L Ma, D Zhang, J Schlessinger, GI Shulman Nature communications 6 (1), 6980, 2015 | 122 | 2015 |
| Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo T Galbo, RJ Perry, MJ Jurczak, JPG Camporez, TC Alves, M Kahn, ... Proceedings of the National Academy of Sciences 110 (31), 12780-12785, 2013 | 117 | 2013 |
