| Valerenic acid potentiates and inhibits GABAA receptors: molecular mechanism and subunit specificity S Khom, I Baburin, E Timin, A Hohaus, G Trauner, B Kopp, S Hering Neuropharmacology 53 (1), 178-187, 2007 | 222 | 2007 |
| Pharmacological properties of GABAA receptors containing γ1 subunits S Khom, I Baburin, EN Timin, A Hohaus, W Sieghart, S Hering Molecular Pharmacology 69 (2), 640-649, 2006 | 124 | 2006 |
| Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid G Trauner, S Khom, I Baburin, B Benedek, S Hering, B Kopp Planta Medica 74 (01), 19-24, 2008 | 112 | 2008 |
| Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala BJ Tunstall, D Kirson, LJ Zallar, SA McConnell, JCM Vendruscolo, CP Ho, ... PLoS biology 17 (4), e2006421, 2019 | 81 | 2019 |
| Valerenic acid derivatives as novel subunit‐selective GABAA receptor ligands –in vitro and in vivo characterization S Khom, B Strommer, J Ramharter, T Schwarz, C Schwarzer, T Erker, ... British journal of pharmacology 161 (1), 65-78, 2010 | 77 | 2010 |
| Microglia control escalation of drinking in alcohol-dependent mice: genomic and synaptic drivers AS Warden, SA Wolfe, S Khom, FP Varodayan, RR Patel, MQ Steinman, ... Biological psychiatry 88 (12), 910-921, 2020 | 76 | 2020 |
| The role of the central amygdala in alcohol dependence M Roberto, D Kirson, S Khom Cold Spring Harbor perspectives in medicine 11 (2), a039339, 2021 | 71 | 2021 |
| Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives A Schöffmann, L Wimmer, D Goldmann, S Khom, J Hintersteiner, ... Journal of medicinal chemistry 57 (13), 5602-5619, 2014 | 60 | 2014 |
| GABAA receptor modulation by piperine and a non-TRPV1 activating derivative S Khom, B Strommer, A Schöffmann, J Hintersteiner, I Baburin, T Erker, ... Biochemical pharmacology 85 (12), 1827-1836, 2013 | 59 | 2013 |
| Bioactivity-Guided Isolation of GABAA Receptor Modulating Constituents from the Rhizomes of Actaea racemosa SS Cicek, S Khom, B Taferner, S Hering, H Stuppner Journal of natural products 73 (12), 2024-2028, 2010 | 49 | 2010 |
| IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala RR Patel, S Khom, MQ Steinman, FP Varodayan, WB Kiosses, ... Brain, behavior, and immunity 75, 208-219, 2019 | 48 | 2019 |
| Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal AJ Roberts, S Khom, M Bajo, R Vlkolinsky, I Polis, C Cates-Gatto, ... Brain, behavior, and immunity 82, 188-202, 2019 | 43 | 2019 |
| HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes HJ Kim, I Baburin, S Khom, S Hering, M Hamburger Planta medica 74 (05), 521-526, 2008 | 43 | 2008 |
| Synthetic, Mechanistic, and Biological Interrogation of Ginkgo biloba Chemical Space En Route to (−)-Bilobalide RM Demoret, MA Baker, M Ohtawa, S Chen, CC Lam, S Khom, M Roberto, ... Journal of the American Chemical Society 142 (43), 18599-18618, 2020 | 40 | 2020 |
| CRF modulates glutamate transmission in the central amygdala of na´ ve and ethanol-dependent rats FP Varodayan, D Correia, D Kirson, S Khom, CS Oleata, G Luu, ... Neuropharmacology 125, 418-428, 2017 | 36 | 2017 |
| Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site‐directed mutagenesis D Luger, G Poli, M Wieder, M Stadler, S Ke, M Ernst, A Hohaus, T Linder, ... British Journal of Pharmacology 172 (22), 5403-5413, 2015 | 35 | 2015 |
| Identification and Characterization of GABAA Receptor Modulatory Diterpenes from Biota orientalis That Decrease Locomotor Activity in Mice J Zaugg, S Khom, D Eigenmann, I Baburin, M Hamburger, S Hering Journal of natural products 74 (8), 1764-1772, 2011 | 33 | 2011 |
| Sex differences in acute alcohol sensitivity of naïve and alcohol dependent central amygdala GABA synapses D Kirson, S Khom, L Rodriguez, SA Wolfe, FP Varodayan, PJ Gandhi, ... Alcohol and Alcoholism 56 (5), 581-588, 2021 | 28 | 2021 |
| GABAA receptor modulators from the Chinese herbal drug Junci medulla–the pith of Juncus effusus J Singhuber, I Baburin, S Khom, M Zehl, E Urban, S Hering, B Kopp Planta medica 78 (05), 455-458, 2012 | 27 | 2012 |
| The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission V Chuong, M Farokhnia, S Khom, CL Pince, SK Elvig, R Vlkolinsky, ... JCI insight 8 (12), 2023 | 25 | 2023 |
Marisa RobertoProfessor of Molecular Medicine, The Scripps Research InstituteVerified email at scripps.edu
