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Timothy M Clay
Timothy M Clay
Verified email at gsk.com
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A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
MA Morse, J Garst, T Osada, S Khan, A Hobeika, TM Clay, N Valente, ...
Journal of translational medicine 3 (1), 1-8, 2005
11672005
Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity
TM Clay, MC Custer, J Sachs, P Hwu, SA Rosenberg, MI Nishimura
The Journal of Immunology 163 (1), 507-513, 1999
5601999
Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines
MA Morse, AC Hobeika, T Osada, D Serra, D Niedzwiecki, HK Lyerly, ...
Blood, The Journal of the American Society of Hematology 112 (3), 610-618, 2008
3742008
The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients
T Osada, G Chong, R Tansik, T Hong, N Spector, R Kumar, HI Hurwitz, ...
Cancer Immunology, Immunotherapy 57 (8), 1115-1124, 2008
3352008
Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations
T Osada, M Chen, XY Yang, I Spasojevic, JB Vandeusen, D Hsu, ...
Cancer research 71 (12), 4172-4182, 2011
2942011
Assays for monitoring cellular immune responses to active immunotherapy of cancer
TM Clay, AC Hobeika, PJ Mosca, HK Lyerly, MA Morse
Clinical Cancer Research 7 (5), 1127-1135, 2001
2562001
Investigation of HIFU-induced anti-tumor immunity in a murine tumor model
Z Hu, XY Yang, Y Liu, GN Sankin, EC Pua, MA Morse, HK Lyerly, TM Clay, ...
Journal of translational medicine 5 (1), 1-11, 2007
2262007
Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)
S Janetzki, KS Panageas, L Ben-Porat, J Boyer, CM Britten, TM Clay, ...
Cancer Immunology, Immunotherapy 57 (3), 303-315, 2008
2232008
Increasing vaccine potency through exosome antigen targeting
ZC Hartman, J Wei, OK Glass, H Guo, G Lei, XY Yang, T Osada, ...
Vaccine 29 (50), 9361-9367, 2011
2202011
Identification of epitope mimics recognized by CTL reactive to the melanoma/melanocyte-derived peptide MART-1 (27-35).
DJ Loftus, C Castelli, TM Clay, P Squarcina, FM Marincola, MI Nishimura, ...
The Journal of experimental medicine 184 (2), 647-657, 1996
2081996
Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA
MA Morse, SK Nair, PJ Mosca, AC Hobeika, TM Clay, Y Deng, ...
Cancer investigation 21 (3), 341-349, 2003
2072003
Evasion of immune responses to introduced human acid α-glucosidase by liver-restricted expression in glycogen storage disease type II
LM Franco, B Sun, X Yang, A Bird, H Zhang, A Schneider, T Brown, ...
Molecular Therapy 12 (5), 876-884, 2005
1922005
CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer
X Wang, T Osada, Y Wang, L Yu, K Sakakura, A Katayama, JB McCarthy, ...
Journal of the National Cancer Institute 102 (19), 1496-1512, 2010
1892010
A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-γ treatment
PJ Mosca, AC Hobeika, TM Clay, SK Nair, EK Thomas, MA Morse, ...
Blood, The Journal of the American Society of Hematology 96 (10), 3499-3504, 2000
1772000
Phase I study utilizing a novel antigen-presenting cell–targeted vaccine with Toll-like receptor stimulation to induce immunity to self-antigens in cancer patients
MA Morse, R Chapman, J Powderly, K Blackwell, T Keler, J Green, ...
Clinical Cancer Research 17 (14), 4844-4853, 2011
1722011
Phase I study of immunization with dendritic cells modified with fowlpox encoding carcinoembryonic antigen and costimulatory molecules
MA Morse, TM Clay, AC Hobeika, T Osada, S Khan, S Chui, ...
Clinical cancer research 11 (8), 3017-3024, 2005
1692005
Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo
ZC Hartman, A Kiang, RS Everett, D Serra, XY Yang, TM Clay, ...
Journal of virology 81 (4), 1796-1812, 2007
1632007
Maximizing the retention of antigen specific lymphocyte function after cryopreservation
ML Disis, C dela Rosa, V Goodell, LY Kuan, JCC Chang, K Kuus-Reichel, ...
Journal of immunological methods 308 (1-2), 13-18, 2006
1622006
A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected …
MA Morse, D Niedzwiecki, JL Marshall, C Garrett, DZ Chang, M Aklilu, ...
Annals of surgery 258 (6), 2013
1562013
HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis
ZC Hartman, XY Yang, O Glass, G Lei, T Osada, SS Dave, MA Morse, ...
Cancer research 71 (13), 4380-4391, 2011
1552011
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