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Rona Graham
Rona Graham
Assistant Professor, University of Sherbrooke
Verified email at usherbrooke.ca - Homepage
Title
Cited by
Cited by
Year
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
SE Andrew, Y Paul Goldberg, B Kremer, H Telenius, J Theilmann, ...
Nature genetics 4 (4), 398-403, 1993
14661993
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
SE Andrew, Y Paul Goldberg, B Kremer, H Telenius, J Theilmann, ...
Nature genetics 4 (4), 398-403, 1993
14601993
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
EJ Slow, J van Raamsdonk, D Rogers, SH Coleman, RK Graham, Y Deng, ...
Human molecular genetics 12 (13), 1555-1567, 2003
9352003
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
YP Goldberg, DW Nicholson, DM Rasper, MA Kalchman, HB Koide, ...
Nature genetics 13 (4), 442-449, 1996
8271996
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
RK Graham, Y Deng, EJ Slow, B Haigh, N Bissada, G Lu, J Pearson, ...
Cell 125 (6), 1179-1191, 2006
8002006
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
S Okamoto, MA Pouladi, M Talantova, D Yao, P Xia, DE Ehrnhoefer, ...
Nature medicine 15 (12), 1407-1413, 2009
629*2009
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice
AJ Milnerwood, CM Gladding, MA Pouladi, AM Kaufman, RM Hines, ...
Neuron 65 (2), 178-190, 2010
5732010
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
M Saleh, JP Vaillancourt, RK Graham, M Huyck, SM Srinivasula, ...
Nature 429 (6987), 75-79, 2004
5262004
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease
CL Wellington, LM Ellerby, CA Gutekunst, D Rogers, S Warby, ...
Journal of Neuroscience 22 (18), 7862-7872, 2002
4972002
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
MA Kalchman, HB Koide, K McCutcheon, RK Graham, K Nichol, ...
Nature genetics 16 (1), 44-53, 1997
4731997
Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme
MA Kalchman, RK Graham, G Xia, HB Koide, JG Hodgson, KC Graham, ...
Journal of Biological Chemistry 271 (32), 19385-19394, 1996
4691996
Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions
EJ Slow, RK Graham, AP Osmand, RS Devon, G Lu, Y Deng, J Pearson, ...
Proceedings of the National Academy of Sciences 102 (32), 11402-11407, 2005
3732005
Molecular analysis of new mutations for Huntington's disease: intermediate alleles and sex of origin effects
YP Goldberg, B Kremer, SE Andrew, J Theilmann, RK Graham, F Squitieri, ...
Nature genetics 5 (2), 174-179, 1993
3131993
Wild‐type huntingtin protects neurons from excitotoxicity
BR Leavitt, JM van Raamsdonk, J Shehadeh, H Fernandes, Z Murphy, ...
Journal of neurochemistry 96 (4), 1121-1129, 2006
2562006
Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice
P Guidetti, GP Bates, RK Graham, MR Hayden, BR Leavitt, ...
Neurobiology of disease 23 (1), 190-197, 2006
1832006
Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin
MA Pouladi, RK Graham, JM Karasinska, Y Xie, RD Santos, Å Petersén, ...
Brain 132 (4), 919-932, 2009
1802009
Huntington disease
NS Caron, GEB Wright, MR Hayden
GeneReviews®[Internet], 2020
1672020
Huntington disease
NS Caron, GEB Wright, MR Hayden
GeneReviews®[Internet], 2020
1672020
Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease
J Shehadeh, HB Fernandes, MMZ Mullins, RK Graham, BR Leavitt, ...
Neurobiology of disease 21 (2), 392-403, 2006
1652006
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease
CE Wang, S Tydlacka, AL Orr, SH Yang, RK Graham, MR Hayden, S Li, ...
Human molecular genetics 17 (17), 2738-2751, 2008
1642008
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