Oxidative nucleophilic substitution of hydrogen versus ring-opening in the reaction of 4-R-2-nitrothiophenes with amines. The crucial effect of 4-alkyl groups L Bianchi, M Maccagno, G Petrillo, F Sancassan, C Tavani, S Morganti, ... The Journal of Organic Chemistry 72 (15), 5771-5777, 2007 | 31 | 2007 |
Nitrobutadienes from β-nitrothiophenes: valuable building-blocks in the overall ring-opening / ring-closure protocol to homo- or hetero-cycles L Bianchi, C Dell’Erba, M Maccagno, S Morganti, G Petrillo, E Rizzato, ... Arkivoc 7, 169-185, 2006 | 30 | 2006 |
2,3-Dinitro-1,3-butadienes: versatile building-blocks from the ring-opening of 3,4-dinitrothiophene L Bianchi, M Maccagno, G Petrillo, F Sancassan, D Spinelli, C Tavani Targets in Heterocyclic Systems: Chemistry and Properties 10, 1-23, 2006 | 26* | 2006 |
From β-Nitrothiophenes to Ring-Fused Nitrobenzenes: An Overall Ring-Enlargement Process via a Facile, Aromatization-Driven, Thermal 6π Electrocyclization L Bianchi, C Dell'Erba, M Maccagno, G Petrillo, E Rizzato, F Sancassan, ... The Journal of Organic Chemistry 70 (22), 8734-8738, 2005 | 26 | 2005 |
α-Oxohydrazones as imine component in the synthesis of 4-functionalized azetidinones by the Staudinger reaction L Bianchi, C Dell'Erba, M Maccagno, A Mugnoli, M Novi, G Petrillo, ... Tetrahedron 59 (51), 10195-10201, 2003 | 24 | 2003 |
Access to Ring-Fused Homo-and Heteroaromatic Derivatives via an Initial Ring-Opening of 3-Nitro-4-(phenylsulfonyl) thiophene L Bianchi, C Dell'Erba, M Maccagno, A Mugnoli, M Novi, G Petrillo, ... The Journal of Organic Chemistry 68 (13), 5254-5260, 2003 | 23 | 2003 |
A new route to thiopyran S,S-dioxide derivatives via an overall ring-enlargement protocol from 3-nitrothiophene L Bianchi, M Maccagno, G Petrillo, E Rizzato, F Sancassan, E Severi, ... Tetrahedron 65 (1), 336-343, 2009 | 21 | 2009 |
An original route to newly-functionalized indoles and carbazoles starting from the ring-opening of nitrothiophenes L Bianchi, G Giorgi, M Maccagno, G Petrillo, C Scapolla, C Tavani Tetrahedron Letters 53 (7), 752-757, 2012 | 20 | 2012 |
Easy access to 4-nitrothiochroman S,S-dioxides via ring-enlargement from 3-nitrobenzo[b]thiophene L Bianchi, C Dell'Erba, M Maccagno, S Morganti, M Novi, G Petrillo, ... Tetrahedron 60 (23), 4967-4973, 2004 | 20 | 2004 |
Butadienic Building Blocks from 2-Nitrothiophene as Precursors of Nitrogen Heterocycles: Intriguing Dichotomic Behavior L Bianchi, G Giorgi, M Maccagno, G Petrillo, V Rocca, F Sancassan, ... The Journal of organic chemistry 72 (24), 9067-9073, 2007 | 18 | 2007 |
Synthesis, in vitro activity and in vivo toxicity of the new 2,3-dinitrobutadiene derivative (1E,3E)-1,4-bis(2-naphthyl)-2,3-dinitro-1,3-butadiene M Viale, G Petrillo, C Aiello, C Fenoglio, C Cordazzo, MA Mariggiò, ... Pharmacological Research 56 (4), 318-328, 2007 | 18 | 2007 |
Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene L Bianchi, M Maccagno, G Petrillo, E Rizzato, F Sancassan, D Spinelli, ... Tetrahedron 67 (42), 8160-8169, 2011 | 17 | 2011 |
Strategies for improving the water solubility of new antitumour nitronaphthylbutadiene derivatives A Fontana, M Viale, S Guernelli, C Gasbarri, E Rizzato, M Maccagno, ... Organic & Biomolecular Chemistry 8 (24), 5674-5681, 2010 | 17 | 2010 |
Sensitivity of different resistant tumour cell lines to the two novel compounds (2Z,4E)-2-methylsulfanyl-5-(1-naphthyl)-4-nitro-2,4-pentadienoate and (1E,3E)-1,4-bis(2-naphthyl … M Viale, G Petrillo, M Maccagno, P Castagnola, C Aiello, C Cordazzo, ... European journal of pharmacology 588 (1), 47-51, 2008 | 17 | 2008 |
Naphthylnitrobutadienes as pharmacologically active molecules: evaluation of the in vivo antitumour activity G Petrillo, C Fenoglio, E Ognio, C Aiello, D Spinelli, MA Mariggiò, ... Investigational New Drugs 25, 535-544, 2007 | 16 | 2007 |
1,4-Bis(1-naphthyl)-2,3-dinitro-1,3-butadiene a novel anticancer compound effective against tumor cell lines characterized by different mechanisms of resistance M Novi, M Ottone, C Dell'Erba, F Barbieri, B Chiavarina, M Maccagno, ... Oncology reports 12 (1), 91-96, 2004 | 16 | 2004 |
A straight access to functionalized carbazoles by tandem reaction between indole and nitrobutadienes L Bianchi, M Maccagno, M Pani, G Petrillo, C Scapolla, C Tavani Tetrahedron 71 (39), 7421-7435, 2015 | 15 | 2015 |
Highly-substituted pyrazoles and pyridazines by MIRC reactions of hydrazone anions and nitrobutadienic fragments L Bianchi, A Carloni-Garaventa, M Maccagno, G Petrillo, C Scapolla, ... Tetrahedron Letters 53 (47), 6394-6400, 2012 | 15 | 2012 |
Versatile Nitrobutadienic Building Blocks from the Ring‐Opening of 2‐and 3‐Nitrothiophenes L Bianchi, M Maccagno, G Petrillo, E Rizzato, F Sancassan, R Severi, ... Targets in Heterocyclic Systems: Chemistry and Properties 11, 1-20, 2008 | 15* | 2008 |
Design, synthesis, and in vitro evaluation of new naphthylnitrobutadienes with potential antiproliferative activity: Toward a structure/activity correlation G Petrillo, MA Mariggiò, C Aiello, C Cordazzo, C Fenoglio, S Morganti, ... Bioorganic & medicinal chemistry 16 (1), 240-247, 2008 | 15 | 2008 |