Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ... Journal of Neuroscience 29 (2), 359-370, 2009 | 1027 | 2009 |
Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, ... Diabetes 61 (6), 1455-1462, 2012 | 219 | 2012 |
Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet R Barbuio, M Milanski, MB Bertolo, MJ Saad, LA Velloso Journal of Endocrinology 194 (3), 539-550, 2007 | 206 | 2007 |
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver DE Cintra, JR Pauli, EP Araújo, JC Moraes, CT de Souza, M Milanski, ... Journal of hepatology 48 (4), 628-637, 2008 | 196 | 2008 |
Low-grade hypothalamic inflammation leads to defective thermogenesis, insulin resistance, and impaired insulin secretion AP Arruda, M Milanski, A Coope, AS Torsoni, E Ropelle, DP Carvalho, ... Endocrinology 152 (4), 1314-1326, 2011 | 193 | 2011 |
AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus A Coope, M Milanski, EP Araújo, M Tambascia, MJA Saad, B Geloneze, ... FEBS letters 582 (10), 1471-1476, 2008 | 172 | 2008 |
Deletion of tumor necrosis factor-α receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis T Romanatto, EA Roman, AP Arruda, RG Denis, C Solon, M Milanski, ... Journal of Biological Chemistry 284 (52), 36213-36222, 2009 | 156 | 2009 |
Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring RO Benatti, AM Melo, FO Borges, LM Ignacio-Souza, LAP Simino, ... British journal of nutrition 111 (12), 2112-2122, 2014 | 125 | 2014 |
Hypothalamic actions of tumor necrosis factor α provide the thermogenic core for the wastage syndrome in cachexia AP Arruda, M Milanski, T Romanatto, C Solon, A Coope, LC Alberici, ... Endocrinology 151 (2), 683-694, 2010 | 89 | 2010 |
Tumor necrosis factor‐α activates signal transduction in hypothalamus and modulates the expression of pro‐inflammatory proteins and orexigenic/anorexigenic neurotransmitters ME Amaral, R Barbuio, M Milanski, T Romanatto, HC Barbosa, W Nadruz, ... Journal of neurochemistry 98 (1), 203-212, 2006 | 73 | 2006 |
TNF-α transiently induces endoplasmic reticulum stress and an incomplete unfolded protein response in the hypothalamus RG Denis, AP Arruda, T Romanatto, M Milanski, A Coope, C Solon, ... Neuroscience 170 (4), 1035-1044, 2010 | 63 | 2010 |
Saturated fatty acids modulate autophagy’s proteins in the hypothalamus M Portovedo, LM Ignacio-Souza, B Bombassaro, A Coope, A Reginato, ... PLoS One 10 (3), e0119850, 2015 | 61 | 2015 |
Defective regulation of the ubiquitin/proteasome system in the hypothalamus of obese male mice LM Ignacio-Souza, B Bombassaro, LB Pascoal, MA Portovedo, DS Razolli, ... Endocrinology 155 (8), 2831-2844, 2014 | 61 | 2014 |
Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation AM Melo, RO Benatti, LM Ignacio-Souza, C Okino, AS Torsoni, M Milanski, ... Metabolism 63 (5), 682-692, 2014 | 60 | 2014 |
Serum levels and mesenteric fat tissue expression of adiponectin and leptin in patients with Crohn's disease VS Rodrigues, M Milanski, JJ Fagundes, AS Torsoni, MLS Ayrizono, ... Clinical & Experimental Immunology 170 (3), 358-364, 2012 | 49 | 2012 |
Lipid overload during gestation and lactation can independently alter lipid homeostasis in offspring and promote metabolic impairment after new challenge to high-fat diet LA de Paula Simino, T de Fante, M Figueiredo Fontana, F Oliveira Borges, ... Nutrition & metabolism 14 (1), 1-15, 2017 | 43 | 2017 |
Diet-induced maternal obesity alters insulin signalling in male mice offspring rechallenged with a high-fat diet in adulthood T Fante, LA Simino, A Reginato, TB Payolla, DCG Vitoréli, M Souza, ... PloS one 11 (8), e0160184, 2016 | 36 | 2016 |
Chaperone insufficiency links TLR4 protein signaling to endoplasmic reticulum stress A Coope, M Milanski, AP Arruda, LM Ignacio-Souza, MJ Saad, GF Anhê, ... Journal of Biological Chemistry 287 (19), 15580-15589, 2012 | 33 | 2012 |
Beet Stalks and Leaves (Beta vulgaris L.) Protect Against High-Fat Diet-Induced Oxidative Damage in the Liver in Mice IM Lorizola, CPB Furlan, M Portovedo, M Milanski, PB Botelho, ... Nutrients 10 (7), 872, 2018 | 32 | 2018 |
Differential expression of pro-inflammatory cytokines and a pro-apoptotic protein in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis RF Leal, CSR Coy, MLS Ayrizono, JJ Fagundes, M Milanski, MJ Saad, ... Techniques in coloproctology 12 (1), 33-38, 2008 | 32 | 2008 |