Daniel Ian Scholes Rosenbloom
Daniel Ian Scholes Rosenbloom
Associate Principal Scientist, Quantitative Pharmacometrics & Pharmacology, Merck Research
Verified email at - Homepage
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Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
YC Ho, L Shan, NN Hosmane, J Wang, SB Laskey, DIS Rosenbloom, ...
Cell 155 (3), 540-551, 2013
Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys
JB Whitney, AL Hill, S Sanisetty, P Penaloza-MacMaster, J Liu, M Shetty, ...
Nature 512 (7512), 74-77, 2014
Clonal evolution of glioblastoma under therapy
J Wang, E Cazzato, E Ladewig, V Frattini, DIS Rosenbloom, S Zairis, ...
Nature genetics 48 (7), 768-776, 2016
Imitation dynamics of vaccination behaviour on social networks
F Fu, DI Rosenbloom, L Wang, MA Nowak
Proceedings of the Royal Society B: Biological Sciences 278 (1702), 42-49, 2011
Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations
GM Laird, CK Bullen, DIS Rosenbloom, AR Martin, AL Hill, CM Durand, ...
The Journal of clinical investigation 125 (5), 1901-1912, 2015
Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics
NN Hosmane, KJ Kwon, KM Bruner, AA Capoferri, S Beg, ...
Journal of Experimental Medicine 214 (4), 959-972, 2017
Viremic relapse after HIV-1 remission in a perinatally infected child
K Luzuriaga, H Gay, C Ziemniak, KB Sanborn, M Somasundaran, ...
New England Journal of Medicine 372 (8), 786-788, 2015
Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1
AL Hill, DIS Rosenbloom, F Fu, MA Nowak, RF Siliciano
Proceedings of the National Academy of Sciences 111 (37), 13475-13480, 2014
Spatiotemporal genomic architecture informs precision oncology in glioblastoma
JK Lee, J Wang, JK Sa, E Ladewig, HO Lee, IH Lee, HJ Kang, ...
Nature genetics 49 (4), 594-599, 2017
Antiretroviral dynamics determines HIV evolution and predicts therapy outcome
DIS Rosenbloom, AL Hill, SA Rabi, RF Siliciano, MA Nowak
Nature Medicine 18 (9), 1378-1385, 2012
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
JK Lee, Z Liu, JK Sa, S Shin, J Wang, M Bordyuh, HJ Cho, O Elliott, T Chu, ...
Nature genetics 50 (10), 1399-1411, 2018
Designing and interpreting limiting dilution assays: general principles and applications to the latent reservoir for human immunodeficiency virus-1
DIS Rosenbloom, O Elliott, AL Hill, TJ Henrich, JM Siliciano, RF Siliciano
Open forum infectious diseases 2 (4), ofv123, 2015
Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance
S Moreno-Gamez, AL Hill, DIS Rosenbloom, DA Petrov, MA Nowak, ...
Proceedings of the National Academy of Sciences 112 (22), E2874-E2883, 2015
Measuring the Frequency of Latent HIV-1 in Resting CD4+ T Cells Using a Limiting Dilution Coculture Assay
GM Laird, DIS Rosenbloom, J Lai, RF Siliciano, JD Siliciano
HIV protocols, 239-253, 2016
Real-time predictions of reservoir size and rebound time during antiretroviral therapy interruption trials for HIV
AL Hill, DIS Rosenbloom, E Goldstein, E Hanhauser, DR Kuritzkes, ...
PLoS pathogens 12 (4), e1005535, 2016
Re-evaluating evolution in the HIV reservoir
DIS Rosenbloom, AL Hill, SB Laskey, RF Siliciano
Nature 551 (7681), E6-E9, 2017
Insight into treatment of HIV infection from viral dynamics models
AL Hill, DIS Rosenbloom, MA Nowak, RF Siliciano
Immunological reviews 285 (1), 9-25, 2018
Topological data analysis generates high-resolution, genome-wide maps of human recombination
PG Camara, DIS Rosenbloom, KJ Emmett, AJ Levine, R Rabadan
Cell systems 3 (1), 83-94, 2016
Asymptomatic shedding of respiratory virus among an ambulatory population across seasons
R Birger, H Morita, D Comito, I Filip, M Galanti, B Lane, C Ligon, ...
Msphere 3 (4), 10.1128/msphere. 00249-18, 2018
Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size
DIS Rosenbloom, P Bacchetti, M Stone, X Deng, RJ Bosch, DD Richman, ...
PLoS computational biology 15 (4), e1006849, 2019
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