| Wnt/β-catenin signaling: components, mechanisms, and diseases BT MacDonald, K Tamai, X He Developmental cell 17 (1), 9-26, 2009 | 6583 | 2009 |
| Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+ 2 A Escayg, BT MacDonald, MH Meisler, S Baulac, G Huberfeld, ... Nature genetics 24 (4), 343-345, 2000 | 1290 | 2000 |
| Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling BT MacDonald, X He Cold Spring Harbor perspectives in biology 4 (12), a007880, 2012 | 654 | 2012 |
| Lrp5 functions in bone to regulate bone mass Y Cui, PJ Niziolek, BT MacDonald, CR Zylstra, N Alenina, DR Robinson, ... Nature medicine 17 (6), 684-691, 2011 | 487 | 2011 |
| SnapShot: noncanonical Wnt signaling pathways MV Semenov, R Habas, BT MacDonald, X He Cell 131 (7), 1378. e1-1378. e2, 2007 | 437 | 2007 |
| A Novel SCN1A Mutation Associated with Generalized Epilepsy with Febrile Seizures Plus—and Prevalence of Variants in Patients with Epilepsy A Escayg, A Heils, BT MacDonald, K Haug, T Sander, MH Meisler The American Journal of Human Genetics 68 (4), 866-873, 2001 | 397 | 2001 |
| Sodium channels SCN1A, SCN2A and SCN3A in familial autism LA Weiss, A Escayg, JA Kearney, M Trudeau, BT MacDonald, M Mori, ... Molecular psychiatry 8 (2), 186-194, 2003 | 358 | 2003 |
| Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies SE Kim, H Huang, M Zhao, X Zhang, A Zhang, MV Semonov, ... Science 340 (6134), 867-870, 2013 | 244 | 2013 |
| A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for β subunit interaction J Spampanato, JA Kearney, G De Haan, DP McEwen, A Escayg, I Aradi, ... Journal of Neuroscience 24 (44), 10022-10034, 2004 | 219 | 2004 |
| Bone mass is inversely proportional to Dkk1 levels in mice BT MacDonald, DM Joiner, SM Oyserman, P Sharma, SA Goldstein, X He, ... Bone 41 (3), 331-339, 2007 | 217 | 2007 |
| SnapShot: Wnt/β-catenin signaling BT MacDonald, MV Semenov, X He Cell 131 (6), 1204. e1-1204. e2, 2007 | 203 | 2007 |
| Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin M Zebisch, Y Xu, C Krastev, BT MacDonald, M Chen, RJC Gilbert, X He, ... Nature communications 4 (1), 2787, 2013 | 191 | 2013 |
| Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation X Zhang, SM Cheong, NG Amado, AH Reis, BT MacDonald, M Zebisch, ... Developmental cell 32 (6), 719-730, 2015 | 180 | 2015 |
| Hypomorphic expression of Dkk1 in the doubleridgemouse: dose dependence and compensatory interactions with Lrp6 BT MacDonald, M Adamska, MH Meisler Oxford University Press for The Company of Biologists Limited 131 (11), 2543 …, 2004 | 165 | 2004 |
| Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation X Zhang, JG Abreu, C Yokota, BT MacDonald, S Singh, KLA Coburn, ... Cell 149 (7), 1565-1577, 2012 | 147 | 2012 |
| Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling S Chen, D Bubeck, BT MacDonald, WX Liang, JH Mao, T Malinauskas, ... Developmental cell 21 (5), 848-861, 2011 | 134 | 2011 |
| Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6 BT MacDonald, C Yokota, K Tamai, X Zeng, X He Journal of biological chemistry 283 (23), 16115-16123, 2008 | 132 | 2008 |
| Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL L Wang, AK Shalek, M Lawrence, R Ding, JT Gaublomme, N Pochet, ... Blood, The Journal of the American Society of Hematology 124 (7), 1089-1098, 2014 | 97 | 2014 |
| Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL L Wang, AK Shalek, M Lawrence, R Ding, JT Gaublomme, N Pochet, ... Blood, The Journal of the American Society of Hematology 124 (7), 1089-1098, 2014 | 97 | 2014 |
| Disulfide bond requirements for active Wnt ligands BT MacDonald, A Hien, X Zhang, O Iranloye, DM Virshup, ML Waterman, ... Journal of Biological Chemistry 289 (26), 18122-18136, 2014 | 94 | 2014 |
