| Subsecond dopamine release promotes cocaine seeking PEM Phillips, GD Stuber, MLAV Heien, RM Wightman, RM Carelli Nature 422 (6932), 614-618, 2003 | 1178 | 2003 |
| A selective role for dopamine in stimulus–reward learning SB Flagel, JJ Clark, TE Robinson, L Mayo, A Czuj, I Willuhn, CA Akers, ... Nature 469 (7328), 53-57, 2011 | 907 | 2011 |
| Dopamine operates as a subsecond modulator of food seeking MF Roitman, GD Stuber, PEM Phillips, RM Wightman, RM Carelli Journal of Neuroscience 24 (6), 1265-1271, 2004 | 740 | 2004 |
| Real-time measurement of dopamine fluctuations after cocaine in the brain of behaving rats MLAV Heien, AS Khan, JL Ariansen, JF Cheer, PEM Phillips, KM Wassum, ... Proceedings of the National Academy of Sciences 102 (29), 10023-10028, 2005 | 455 | 2005 |
| Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization SM Ferguson, D Eskenazi, M Ishikawa, MJ Wanat, PEM Phillips, Y Dong, ... Nature neuroscience 14 (1), 22-24, 2011 | 421 | 2011 |
| Prolonged dopamine signalling in striatum signals proximity and value of distant rewards MW Howe, PL Tierney, SG Sandberg, PEM Phillips, AM Graybiel nature 500 (7464), 575-579, 2013 | 420 | 2013 |
| Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior LS Zweifel, JG Parker, CJ Lobb, A Rainwater, VZ Wall, JP Fadok, ... Proceedings of the national academy of sciences 106 (18), 7281-7288, 2009 | 407 | 2009 |
| Cannabinoids enhance subsecond dopamine release in the nucleus accumbens of awake rats JF Cheer, KM Wassum, MLAV Heien, PEM Phillips, RM Wightman Journal of Neuroscience 24 (18), 4393-4400, 2004 | 375 | 2004 |
| Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity MLAV Heien, PEM Phillips, GD Stuber, AT Seipel, RM Wightman Analyst 128 (12), 1413-1419, 2003 | 362 | 2003 |
| An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction SB Flagel, TE Robinson, JJ Clark, SM Clinton, SJ Watson, P Seeman, ... Neuropsychopharmacology 35 (2), 388-400, 2010 | 355 | 2010 |
| Weighing up the benefits of work: behavioral and neural analyses of effort-related decision making ME Walton, SW Kennerley, DM Bannerman, PEM Phillips, ... Neural networks 19 (8), 1302-1314, 2006 | 353 | 2006 |
| Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation JF Cheer, KM Wassum, LA Sombers, MLAV Heien, JL Ariansen, ... Journal of Neuroscience 27 (4), 791-795, 2007 | 348 | 2007 |
| Chronic microsensors for longitudinal, subsecond dopamine detection in behaving animals JJ Clark, SG Sandberg, MJ Wanat, JO Gan, EA Horne, AS Hart, CA Akers, ... Nature methods 7 (2), 126-129, 2010 | 316 | 2010 |
| Real‐time decoding of dopamine concentration changes in the caudate–putamen during tonic and phasic firing BJ Venton, H Zhang, PA Garris, PEM Phillips, D Sulzer, RM Wightman Journal of neurochemistry 87 (5), 1284-1295, 2003 | 310 | 2003 |
| Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive JC Lemos, MJ Wanat, JS Smith, BAS Reyes, NG Hollon, ... Nature 490 (7420), 402-406, 2012 | 262 | 2012 |
| Calculating utility: preclinical evidence for cost–benefit analysis by mesolimbic dopamine PEM Phillips, ME Walton, TC Jhou Psychopharmacology 191 (3), 483-495, 2007 | 258 | 2007 |
| Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine JO Gan, ME Walton, PEM Phillips Nature neuroscience 13 (1), 25-27, 2010 | 251 | 2010 |
| Phasic dopamine release in the rat nucleus accumbens symmetrically encodes a reward prediction error term AS Hart, RB Rutledge, PW Glimcher, PEM Phillips Journal of Neuroscience 34 (3), 698-704, 2014 | 248 | 2014 |
| Mesocortical dopamine neurons operate in distinct temporal domains using multimodal signaling A Lavin, L Nogueira, CC Lapish, RM Wightman, PEM Phillips, ... Journal of Neuroscience 25 (20), 5013-5023, 2005 | 246 | 2005 |
| Corticotropin‐releasing factor increases mouse ventral tegmental area dopamine neuron firing through a protein kinase C‐dependent enhancement of Ih MJ Wanat, FW Hopf, GD Stuber, PEM Phillips, A Bonci The Journal of physiology 586 (8), 2157-2170, 2008 | 244 | 2008 |
R. Mark WightmanProfessor of Chemistry, University of North Carolina at chapel hillVerified email at unc.edu
