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Christopher E. Nelson
Christopher E. Nelson
Verified email at uark.edu - Homepage
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Cited by
Year
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ...
Science 351 (6271), 403-407, 2016
13182016
Ex Vivo Red Blood Cell Hemolysis Assay for the Evaluation of pH-responsive Endosomolytic Agents for Cytosolic Delivery of Biomacromolecular Drugs.
BC Evans, CE Nelson, SS Yu, KR Beavers, AJ Kim, H Li, HM Nelson, ...
Journal of visualized experiments: JoVE, 2012
4802012
Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, ...
Nature medicine 25 (3), 427-432, 2019
3872019
Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo
CE Nelson, JR Kintzing, A Hanna, JM Shannon, MK Gupta, CL Duvall
ACS nano 7 (10), 8870-8880, 2013
3352013
ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease
KM Poole, CE Nelson, RV Joshi, JR Martin, MK Gupta, SC Haws, ...
Biomaterials 41, 166-175, 2015
2002015
Poly (PS-b-DMA) micelles for reactive oxygen species triggered drug release
MK Gupta, TA Meyer, CE Nelson, CL Duvall
Journal of Controlled Release 162 (3), 591-598, 2012
1852012
Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis In Vivo
CE Nelson, AJ Kim, EJ Adolph, MK Gupta, F Yu, KM Hocking, ...
Advanced Materials 26 (4), 607-614, 2014
1792014
Macrophage-Specific RNA Interference Targeting via “Click”, Mannosylated Polymeric Micelles
SS Yu, CM Lau, WJ Barham, HM Onishko, CE Nelson, H Li, CA Smith, ...
Molecular pharmaceutics 10 (3), 975-987, 2013
1642013
Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers
M Miteva, KC Kirkbride, KV Kilchrist, TA Werfel, H Li, CE Nelson, ...
Biomaterials 38, 97-107, 2015
1532015
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, ...
Nature communications 9 (1), 1-9, 2018
1482018
Matrix Metalloproteinase Responsive, Proximity‐Activated Polymeric Nanoparticles for siRNA Delivery
H Li, SS Yu, M Miteva, CE Nelson, T Werfel, TD Giorgio, CL Duvall
Advanced Functional Materials 23 (24), 3040-3052, 2013
1312013
Engineering Delivery Vehicles for Genome Editing
CE Nelson, CA Gersbach
Annual review of chemical and biomolecular engineering 7, 637-662, 2016
1192016
Technologies for controlled, local delivery of siRNA
SM Sarett, CE Nelson, CL Duvall
Journal of Controlled Release 218, 94-113, 2015
952015
AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice
CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, ...
JCI insight 3 (23), 2018
942018
MiRNA inhibition in tissue engineering and regenerative medicine
KR Beavers, CE Nelson, CL Duvall
Advanced drug delivery reviews 88, 123-137, 2015
912015
Sustained local delivery of siRNA from an injectable scaffold
CE Nelson, MK Gupta, EJ Adolph, JM Shannon, SA Guelcher, CL Duvall
Biomaterials 33 (4), 1154-1161, 2012
882012
Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models
CH Hakim, SRP Kumar, DO Pérez-López, NB Wasala, D Zhang, Y Yue, ...
Nature communications 12 (1), 1-12, 2021
852021
Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells
A Pickar-Oliver, JB Black, MM Lewis, KJ Mutchnick, TS Klann, KA Gilcrest, ...
Nature biotechnology 37 (12), 1493-1501, 2019
852019
Local Delivery of PHD2 siRNA from ROS‐Degradable Scaffolds to Promote Diabetic Wound Healing
JR Martin, CE Nelson, MK Gupta, F Yu, SM Sarett, KM Hocking, ...
Advanced healthcare materials 5 (21), 2751-2757, 2016
832016
Genome engineering: a new approach to gene therapy for neuromuscular disorders
CE Nelson, JN Robinson-Hamm, CA Gersbach
Nature Reviews Neurology 13 (11), 647-661, 2017
732017
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