| Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers BG Bitler, KM Aird, A Garipov, H Li, M Amatangelo, AV Kossenkov, ... Nature medicine 21 (3), 231-238, 2015 | 616 | 2015 |
| sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ... Nature 532 (7598), 250-254, 2016 | 354 | 2016 |
| Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence KM Aird, G Zhang, H Li, Z Tu, BG Bitler, A Garipov, H Wu, Z Wei, ... Cell reports 3 (4), 1252-1265, 2013 | 286 | 2013 |
| NAD+ metabolism governs the proinflammatory senescence-associated secretome T Nacarelli, L Lau, T Fukumoto, J Zundell, N Fatkhutdinov, S Wu, KM Aird, ... Nature cell biology 21 (3), 397-407, 2019 | 272 | 2019 |
| ARID1A-mutated ovarian cancers depend on HDAC6 activity BG Bitler, S Wu, PH Park, Y Hai, KM Aird, Y Wang, Y Zhai, AV Kossenkov, ... Nature cell biology 19 (8), 962-973, 2017 | 213 | 2017 |
| PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion MC Caino, JC Ghosh, YC Chae, V Vaira, DB Rivadeneira, A Faversani, ... Proceedings of the National Academy of Sciences 112 (28), 8638-8643, 2015 | 205 | 2015 |
| Detection of senescence-associated heterochromatin foci (SAHF) KM Aird, R Zhang Cell Senescence: Methods and Protocols, 185-196, 2013 | 162 | 2013 |
| HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci KM Aird, O Iwasaki, AV Kossenkov, H Tanizawa, N Fatkhutdinov, BG Bitler, ... Journal of Cell Biology 215 (3), 325-334, 2016 | 153 | 2016 |
| Nucleotide metabolism, oncogene-induced senescence and cancer KM Aird, R Zhang Cancer letters 356 (2), 204-210, 2015 | 153 | 2015 |
| ATM couples replication stress and metabolic reprogramming during cellular senescence KM Aird, AJ Worth, NW Snyder, JV Lee, S Sivanand, Q Liu, IA Blair, ... Cell reports 11 (6), 893-901, 2015 | 105 | 2015 |
| Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence Z Tu, KM Aird, BG Bitler, JP Nicodemus, N Beeharry, B Xia, TJ Yen, ... Developmental cell 21 (6), 1077-1091, 2011 | 99 | 2011 |
| XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells JL Allensworth, KM Aird, AJ Aldrich, I Batinic-Haberle, GR Devi Molecular cancer therapeutics 11 (7), 1518-1527, 2012 | 88 | 2012 |
| X-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor KM Aird, RB Ghanayem, S Peplinski, HK Lyerly, GR Devi Molecular cancer therapeutics 9 (5), 1432-1442, 2010 | 87 | 2010 |
| Suppression of p16 induces mTORC1-mediated nucleotide metabolic reprogramming R Buj, CW Chen, ES Dahl, KE Leon, R Kuskovsky, N Maglakelidze, ... Cell reports 28 (8), 1971-1980. e8, 2019 | 85* | 2019 |
| Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression KM Aird, X Ding, A Baras, J Wei, MA Morse, T Clay, HK Lyerly, GR Devi Molecular cancer therapeutics 7 (1), 38-47, 2008 | 84 | 2008 |
| Susceptibility to tuberculosis: clues from studies with inbred and outbred New Zealand White rabbits SE Dorman, CL Hatem, S Tyagi, K Aird, J Lopez-Molina, MLM Pitt, ... Infection and immunity 72 (3), 1700-1705, 2004 | 82 | 2004 |
| SPOP E3 ubiquitin ligase adaptor promotes cellular senescence by degrading the SENP7 deSUMOylase H Zhu, S Ren, BG Bitler, KM Aird, Z Tu, E Skordalakes, Y Zhu, J Yan, ... Cell reports 13 (6), 1183-1193, 2015 | 75 | 2015 |
| Deoxyribonucleotide triphosphate metabolism in cancer and metabolic disease R Buj, KM Aird Frontiers in endocrinology 9, 362600, 2018 | 67 | 2018 |
| Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration ZI Thomas, W Gibson, JZ Sexton, KM Aird, SM Ingram, A Aldrich, ... British journal of cancer 104 (10), 1575-1586, 2011 | 65 | 2011 |
| EglN2 associates with the NRF 1‐PGC 1α complex and controls mitochondrial function in breast cancer J Zhang, C Wang, X Chen, M Takada, C Fan, X Zheng, H Wen, Y Liu, ... The EMBO journal 34 (23), 2953-2970, 2015 | 64 | 2015 |
