A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo Y Liu, Y Cao, W Zhang, S Bergmeier, Y Qian, H Akbar, R Colvin, J Ding, ... Molecular cancer therapeutics 11 (8), 1672-1682, 2012 | 574 | 2012 |
The Warburg effect: evolving interpretations of an established concept X Chen, Y Qian, S Wu Free Radical Biology and Medicine 79, 253-263, 2015 | 245 | 2015 |
Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells Y Qian, X Wang, Y Liu, Y Li, RA Colvin, L Tong, S Wu, X Chen Cancer letters 351 (2), 242-251, 2014 | 135 | 2014 |
Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms Y Qian, X Wang, Y Li, Y Cao, X Chen Molecular Cancer Research 14 (11), 1087-1096, 2016 | 101 | 2016 |
Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP … X Wang, Y Li, Y Qian, Y Cao, P Shriwas, H Zhang, X Chen Oncotarget 8 (50), 87860, 2017 | 77 | 2017 |
Mechanisms in endocrinology: lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects? R Basu, Y Qian, JJ Kopchick European Journal of Endocrinology 178 (5), R155-R181, 2018 | 60 | 2018 |
Biological and biomedical functions of Penta-O-galloyl-d-glucose and its derivatives Y Cao, KB Himmeldirk, Y Qian, Y Ren, A Malki, X Chen Journal of natural medicines 68, 465-472, 2014 | 58 | 2014 |
Growth hormone and the epithelial-to-mesenchymal transition AL Brittain, R Basu, Y Qian, JJ Kopchick The Journal of Clinical Endocrinology & Metabolism 102 (10), 3662-3673, 2017 | 54 | 2017 |
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells T Tuccinardi, C Granchi, J Iegre, I Paterni, S Bertini, M Macchia, ... Bioorganic & medicinal chemistry letters 23 (24), 6923-6927, 2013 | 54 | 2013 |
Adipocyte-specific GH receptor–null (AdGHRKO) mice have enhanced insulin sensitivity with reduced liver triglycerides EO List, DE Berryman, M Buchman, C Parker, K Funk, S Bell, ... Endocrinology 160 (1), 68-80, 2019 | 45 | 2019 |
Constituents of an Extract of Cryptocarya rubra Housed in a Repository with Cytotoxic and Glucose Transport Inhibitory Effects Y Ren, C Yuan, Y Qian, HB Chai, X Chen, M Goetz, AD Kinghorn Journal of natural products 77 (3), 550-556, 2014 | 45 | 2014 |
GH knockout mice have increased subcutaneous adipose tissue with decreased fibrosis and enhanced insulin sensitivity EO List, DE Berryman, M Buchman, EA Jensen, K Funk, S Duran-Ortiz, ... Endocrinology 160 (7), 1743-1756, 2019 | 42 | 2019 |
Inhibitors of glucose transport and glycolysis as novel anticancer therapeutics Y Qian, X Wang, X Chen World Journal of Translational Medicine 3 (2), 37-57, 2014 | 41 | 2014 |
Growth hormone receptor gene disruption in mature‐adult mice improves male insulin sensitivity and extends female lifespan S Duran‐Ortiz, EO List, Y Ikeno, J Young, R Basu, S Bell, T McHugh, ... Aging cell 20 (12), e13506, 2021 | 33 | 2021 |
A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism P Shriwas, D Roberts, Y Li, L Wang, Y Qian, S Bergmeier, J Hines, ... Cancer & Metabolism 9, 1-14, 2021 | 31 | 2021 |
Cardiac-specific disruption of GH receptor alters glucose homeostasis while maintaining normal cardiac performance in adult male mice A Jara, X Liu, D Sim, CM Benner, S Duran-Ortiz, Y Qian, EO List, ... Endocrinology 157 (5), 1929-1941, 2016 | 27 | 2016 |
Down-regulation of 67LR reduces the migratory activity of human glioma cells in vitro FX Chen, YR Qian, YH Duan, WW Ren, Y Yang, CC Zhang, YM Qiu, YH Ji Brain research bulletin 79 (6), 402-408, 2009 | 24 | 2009 |
Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells C Granchi, Y Qian, HY Lee, I Paterni, C Pasero, J Iegre, KE Carlson, ... ChemMedChem 10 (11), 1892-1900, 2015 | 23 | 2015 |
Mice with gene alterations in the GH and IGF family Y Qian, DE Berryman, R Basu, EO List, S Okada, JA Young, EA Jensen, ... Pituitary, 1-51, 2022 | 22 | 2022 |
Growth hormone upregulates melanocyte-inducing transcription factor expression and activity via JAK2-STAT5 and SRC signaling in GH receptor-positive human melanoma R Basu, P Kulkarni, Y Qian, C Walsh, P Arora, E Davis, S Duran-Ortiz, ... Cancers 11 (9), 1352, 2019 | 22 | 2019 |