Roberto J. Botelho
Roberto J. Botelho
Department of Chemistry and Biology, Toronto Metropolitan University
Verified email at - Homepage
Cited by
Cited by
Phagosome maturation: aging gracefully
OV Vieira, RJ Botelho, S Grinstein
Biochemical Journal 366 (3), 689-704, 2002
Localized biphasic changes in phosphatidylinositol-4, 5-bisphosphate at sites of phagocytosis
RJ Botelho, M Teruel, R Dierckman, R Anderson, A Wells, JD York, ...
The Journal of cell biology 151 (7), 1353-1368, 2000
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation
OV Vieira, RJ Botelho, L Rameh, SM Brachmann, T Matsuo, ...
The Journal of cell biology 155 (1), 19-26, 2001
Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis
CC Scott, W Dobson, RJ Botelho, N Coady-Osberg, P Chavrier, ...
The Journal of cell biology 169 (1), 139-149, 2005
Phagosome maturation: a few bugs in the system
CC Scott, RJ Botelho, S Grinstein
The journal of membrane biology 193, 137-152, 2003
Phosphatidylinositol‐3,5‐Bisphosphate: No Longer the Poor PIP2
CY Ho, TA Alghamdi, RJ Botelho
Traffic 13 (1), 1-8, 2012
Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3, 5-bisphosphate
JA Efe, RJ Botelho, SD Emr
Molecular biology of the cell 18 (11), 4232-4244, 2007
Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis
H Gu, RJ Botelho, M Yu, S Grinstein, BG Neel
The Journal of cell biology 161 (6), 1151-1161, 2003
Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase
RJ Botelho, JA Efe, D Teis, SD Emr
Molecular biology of the cell 19 (10), 4273-4286, 2008
Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages
A Mrakovic, JG Kay, W Furuya, JH Brumell, RJ Botelho
Traffic 13 (12), 1667-1679, 2012
Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcγRIIA receptors
GP Downey, RJ Botelho, JR Butler, Y Moltyaner, P Chien, AD Schreiber, ...
Journal of Biological Chemistry 274 (40), 28436-28444, 1999
The lysosome signaling platform: adapting with the times
S Inpanathan, RJ Botelho
Frontiers in cell and developmental biology 7, 113, 2019
Phagocytosis enhances lysosomal and bactericidal properties by activating the transcription factor TFEB
MA Gray, CH Choy, RM Dayam, E Ospina-Escobar, A Somerville, X Xiao, ...
Current Biology 26 (15), 1955-1964, 2016
RJ Botelho, S Grinstein
Current Biology 21 (14), R533-R538, 2011
Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence
CH Choy, G Saffi, MA Gray, C Wallace, RM Dayam, ZYA Ou, G Lenk, ...
Journal of cell science 131 (10), jcs213587, 2018
mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells
A Saric, VEB Hipolito, JG Kay, J Canton, CN Antonescu, RJ Botelho
Molecular Biology of the Cell 27 (2), 321-333, 2016
The Phosphoinositide‐Gated Lysosomal Ca2+ Channel, TRPML1, Is Required for Phagosome Maturation
RM Dayam, A Saric, RE Shilliday, RJ Botelho
Traffic 16 (9), 1010-1026, 2015
The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology
JA Efe, RJ Botelho, SD Emr
Current opinion in cell biology 17 (4), 402-408, 2005
PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages
GHE Kim, RM Dayam, A Prashar, M Terebiznik, RJ Botelho
Traffic 15 (10), 1143-1163, 2014
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis
GD Fairn, K Ogata, RJ Botelho, PD Stahl, RA Anderson, P De Camilli, ...
Journal of cell biology 187 (5), 701-714, 2009
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