Esther Gan
Esther Gan
Duke-NUS Medical School
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Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development
R de Alwis, S Chen, ES Gan, EE Ooi
EBioMedicine 55, 102768, 2020
Dengue virus activates cGAS through the release of mitochondrial DNA
B Sun, KB Sundstr÷m, JJ Chew, P Bist, ES Gan, HC Tan, KC Goh, ...
Scientific Reports 7 (1), 1-8, 2017
Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity
KR Chan, X Wang, WAA Saron, ES Gan, HC Tan, DZL Mok, SLX Zhang, ...
Nature microbiology 1 (12), 1-10, 2016
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice
R de Alwis, ES Gan, S Chen, YS Leong, HC Tan, SL Zhang, C Yau, ...
Molecular Therapy 29 (6), 1970-1983, 2021
Molecular determinants of plaque size as an indicator of dengue virus attenuation
KCM Goh, CK Tang, DC Norton, ES Gan, HC Tan, B Sun, A Syenina, ...
Scientific reports 6 (1), 1-11, 2016
The mechanistic role of antibodies to dengue virus in protection and disease pathogenesis
ES Gan, DHR Ting, KR Chan
Expert review of anti-infective therapy 15 (2), 111-119, 2017
A systematic approach to the development of a safe live attenuated Zika vaccine
SS Kwek, S Watanabe, KR Chan, EZ Ong, HC Tan, WC Ng, MTX Nguyen, ...
Nature communications 9 (1), 1-13, 2018
Dengue virus compartmentalization during antibody-enhanced infection
EZ Ong, SL Zhang, HC Tan, ES Gan, KR Chan, EE Ooi
Scientific reports 7 (1), 1-9, 2017
Metabolic perturbations and cellular stress underpin susceptibility to symptomatic live-attenuated yellow fever infection
KR Chan, ES Gan, CYY Chan, C Liang, JZH Low, SLX Zhang, EZ Ong, ...
Nature medicine 25 (8), 1218-1224, 2019
Hypoxia enhances antibody‐dependent dengue virus infection
ES Gan, WF Cheong, KR Chan, EZ Ong, X Chai, HC Tan, S Ghosh, ...
The EMBO journal 36 (10), 1348-1363, 2017
Rational engineering and characterization of an mAb that neutralizes Zika virus by targeting a mutationally constrained quaternary epitope
K Tharakaraman, S Watanabe, KR Chan, J Huan, V Subramanian, ...
Cell host & microbe 23 (5), 618-627. e6, 2018
Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes
ES Gan, HC Tan, DHT Le, TT Huynh, B Wills, NG Seidah, EE Ooi, ...
The Journal of clinical investigation 130 (10), 2020
Antibody-Dependent dengue virus entry modulates cell intrinsic responses for enhanced infection
CYY Chan, JZH Low, ES Gan, EZ Ong, SLX Zhang, HC Tan, X Chai, ...
Msphere 4 (5), e00528-19, 2019
Positive epistasis between viral polymerase and the 3′ untranslated region of its genome reveals the epidemiologic fitness of dengue virus
A Syenina, D Vijaykrishna, ES Gan, HC Tan, MM Choy, ...
Proceedings of the National Academy of Sciences 117 (20), 11038-11047, 2020
Identification and in vivo efficacy assessment of approved orally bioavailable human host protein-targeting drugs with broad anti-influenza A activity
T Enkirch, S Sauber, DE Anderson, ES Gan, D Kenanov, S Maurer-Stroh, ...
Frontiers in immunology 10, 1097, 2019
Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development. EBioMedicine 2020; 55: 102768
R De Alwis, S Chen, ES Gan, EE Ooi
PUBMED, 2020
Oxygen: viral friend or foe?
ES Gan, EE Ooi
Virology Journal 17 (1), 1-12, 2020
Impact of Immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development. EBioMedicine. 2020
R de Alwis, S Chen, ES Gan, EE Ooi
Epub 04/16/2020. https://doi. org/10. 1016/j. ebiom. 2020.102768 PubMedá…, 2020
Genomic signature of early T-cell response is associated with lower antibody titer threshold for sterilizing immunity
EZ Ong, ES Gan, R de Alwis, L Wijaya, XM Ong, M Zhang, AWL Wong, ...
Antiviral research 166, 35-41, 2019
A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection
ES Gan, A Syenina, M Linster, B Ng, SL Zhang, S Watanabe, ...
Antiviral research 193, 105138, 2021
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