| Wnt addiction of genetically defined cancers reversed by PORCN inhibition B Madan, Z Ke, N Harmston, SY Ho, AO Frois, J Alam, DA Jeyaraj, ... Oncogene 35 (17), 2197-2207, 2016 | 290 | 2016 |
| Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation N Harmston, E Ing-Simmons, G Tan, M Perry, M Merkenschlager, ... Nature communications 8 (1), 441, 2017 | 159 | 2017 |
| Chromatin and epigenetic features of long-range gene regulation N Harmston, B Lenhard Nucleic acids research 41 (15), 7185-7199, 2013 | 121 | 2013 |
| The mystery of extreme non-coding conservation N Harmston, A Barešić, B Lenhard Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 84 | 2013 |
| Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease C Ferrari Bardile, M Garcia-Miralles, NS Caron, NA Rayan, SR Langley, ... Proceedings of the National Academy of Sciences 116 (19), 9622-9627, 2019 | 68 | 2019 |
| Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk A Moreno-Moral, M Bagnati, S Koturan, JH Ko, C Fonseca, N Harmston, ... Annals of the rheumatic diseases 77 (4), 596-601, 2018 | 61 | 2018 |
| Wnt proteins synergize to activate β-catenin signaling A Alok, Z Lei, NS Jagannathan, S Kaur, N Harmston, SG Rozen, ... Journal of Cell Science 130 (9), 1532-1544, 2017 | 61 | 2017 |
| What the papers say: Text mining for genomics and systems biology N Harmston, W Filsell, MPH Stumpf Human genomics 5, 1-13, 2010 | 59 | 2010 |
| Unbiased profiling of isogenic Huntington disease hPSC-derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, ... Cell Reports 26 (9), 2494-2508. e7, 2019 | 53 | 2019 |
| GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data N Harmston, E Ing-Simmons, M Perry, A Barešić, B Lenhard BMC genomics 16, 1-9, 2015 | 47 | 2015 |
| Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis B Madan, N Harmston, G Nallan, A Montoya, P Faull, E Petretto, ... The Journal of clinical investigation 128 (12), 5620-5633, 2019 | 46 | 2019 |
| WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling H Chen, A Moreno-Moral, F Pesce, N Devapragash, M Mancini, EL Heng, ... Nature communications 10 (1), 3616, 2019 | 41 | 2019 |
| In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors L Yap, JW Wang, A Moreno-Moral, LY Chong, Y Sun, N Harmston, ... Cell reports 26 (12), 3231-3245. e9, 2019 | 36 | 2019 |
| Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture MS Tjin, AWC Chua, A Moreno-Moral, LY Chong, PY Tang, NP Harmston, ... Nature communications 9 (1), 4432, 2018 | 28 | 2018 |
| WNT inhibition creates a BRCA‐like state in Wnt‐addicted cancer A Kaur, JYS Lim, S Sepramaniam, S Patnaik, N Harmston, MA Lee, ... EMBO molecular medicine 13 (4), e13349, 2021 | 23 | 2021 |
| The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt InhibitionRNF43 Mutations That Predict Wnt Inhibitor Sensitivity J Yu, PAM Yusoff, DTJ Woutersen, P Goh, N Harmston, R Smits, ... Cancer Research 80 (24), 5619-5632, 2020 | 23 | 2020 |
| Widespread Repression of Gene Expression in Cancer by a Wnt/β-Catenin/MAPK PathwayWnt Repression of Gene Expression via MAPK Pathway N Harmston, JYS Lim, O Arqués, HG Palmer, E Petretto, DM Virshup, ... Cancer Research 81 (2), 464-475, 2021 | 16 | 2021 |
| Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing M Bagnati, A Moreno-Moral, JH Ko, J Nicod, N Harmston, M Imprialou, ... JCI insight 4 (2), 2019 | 15 | 2019 |
| A Bayesian approach for analysis of whole-genome bisulfite sequencing data identifies disease-associated changes in DNA methylation OJL Rackham, SR Langley, T Oates, E Vradi, N Harmston, PK Srivastava, ... Genetics 205 (4), 1443-1458, 2017 | 13 | 2017 |
| Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation S Liu, N Harmston, TL Glaser, Y Wong, Z Zhong, B Madan, DM Virshup, ... Genome Medicine 12 (1), 1-22, 2020 | 11 | 2020 |
Enrico PetrettoAssoc. Professor & Director @ Centre for Computational Biology of Duke-NUS Medical School, SingaporeVerified email at duke-nus.edu.sg
