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Nathan Harmston
Nathan Harmston
Other namesNathan Peter Harmston
Yale-NUS / Duke-NUS
Verified email at yale-nus.edu.sg
Title
Cited by
Cited by
Year
Wnt addiction of genetically defined cancers reversed by PORCN inhibition
B Madan, Z Ke, N Harmston, SY Ho, AO Frois, J Alam, DA Jeyaraj, ...
Oncogene 35 (17), 2197-2207, 2016
2902016
Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation
N Harmston, E Ing-Simmons, G Tan, M Perry, M Merkenschlager, ...
Nature communications 8 (1), 441, 2017
1592017
Chromatin and epigenetic features of long-range gene regulation
N Harmston, B Lenhard
Nucleic acids research 41 (15), 7185-7199, 2013
1212013
The mystery of extreme non-coding conservation
N Harmston, A Barešić, B Lenhard
Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013
842013
Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease
C Ferrari Bardile, M Garcia-Miralles, NS Caron, NA Rayan, SR Langley, ...
Proceedings of the National Academy of Sciences 116 (19), 9622-9627, 2019
682019
Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk
A Moreno-Moral, M Bagnati, S Koturan, JH Ko, C Fonseca, N Harmston, ...
Annals of the rheumatic diseases 77 (4), 596-601, 2018
612018
Wnt proteins synergize to activate β-catenin signaling
A Alok, Z Lei, NS Jagannathan, S Kaur, N Harmston, SG Rozen, ...
Journal of Cell Science 130 (9), 1532-1544, 2017
612017
What the papers say: Text mining for genomics and systems biology
N Harmston, W Filsell, MPH Stumpf
Human genomics 5, 1-13, 2010
592010
Unbiased profiling of isogenic Huntington disease hPSC-derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects
J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, ...
Cell Reports 26 (9), 2494-2508. e7, 2019
532019
GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data
N Harmston, E Ing-Simmons, M Perry, A Barešić, B Lenhard
BMC genomics 16, 1-9, 2015
472015
Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis
B Madan, N Harmston, G Nallan, A Montoya, P Faull, E Petretto, ...
The Journal of clinical investigation 128 (12), 5620-5633, 2019
462019
WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling
H Chen, A Moreno-Moral, F Pesce, N Devapragash, M Mancini, EL Heng, ...
Nature communications 10 (1), 3616, 2019
412019
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors
L Yap, JW Wang, A Moreno-Moral, LY Chong, Y Sun, N Harmston, ...
Cell reports 26 (12), 3231-3245. e9, 2019
362019
Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture
MS Tjin, AWC Chua, A Moreno-Moral, LY Chong, PY Tang, NP Harmston, ...
Nature communications 9 (1), 4432, 2018
282018
WNT inhibition creates a BRCA‐like state in Wnt‐addicted cancer
A Kaur, JYS Lim, S Sepramaniam, S Patnaik, N Harmston, MA Lee, ...
EMBO molecular medicine 13 (4), e13349, 2021
232021
The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt InhibitionRNF43 Mutations That Predict Wnt Inhibitor Sensitivity
J Yu, PAM Yusoff, DTJ Woutersen, P Goh, N Harmston, R Smits, ...
Cancer Research 80 (24), 5619-5632, 2020
232020
Widespread Repression of Gene Expression in Cancer by a Wnt/β-Catenin/MAPK PathwayWnt Repression of Gene Expression via MAPK Pathway
N Harmston, JYS Lim, O Arqués, HG Palmer, E Petretto, DM Virshup, ...
Cancer Research 81 (2), 464-475, 2021
162021
Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing
M Bagnati, A Moreno-Moral, JH Ko, J Nicod, N Harmston, M Imprialou, ...
JCI insight 4 (2), 2019
152019
A Bayesian approach for analysis of whole-genome bisulfite sequencing data identifies disease-associated changes in DNA methylation
OJL Rackham, SR Langley, T Oates, E Vradi, N Harmston, PK Srivastava, ...
Genetics 205 (4), 1443-1458, 2017
132017
Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation
S Liu, N Harmston, TL Glaser, Y Wong, Z Zhong, B Madan, DM Virshup, ...
Genome Medicine 12 (1), 1-22, 2020
112020
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Articles 1–20