Crystal structure of the 14-subunit RNA polymerase I C Fernández-Tornero, M Moreno-Morcillo, UJ Rashid, NMI Taylor, ... Nature 502 (7473), 644-649, 2013 | 226 | 2013 |
Aldose reductase structures: implications for mechanism and inhibition O El-Kabbani, F Ruiz, C Darmanin, RPT Chung Cellular and Molecular Life Sciences CMLS 61, 750-762, 2004 | 157 | 2004 |
The Binding of Triclosan to SmeT, the Repressor of the Multidrug Efflux Pump SmeDEF, Induces Antibiotic Resistance in Stenotrophomonas maltophilia A Hernández, FM Ruiz, A Romero, JL Martínez PLoS pathogens 7 (6), e1002103, 2011 | 119 | 2011 |
Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding … O El‐Kabbani, C Darmanin, TR Schneider, I Hazemann, F Ruiz, M Oka, ... Proteins: Structure, Function, and Bioinformatics 55 (4), 805-813, 2004 | 117 | 2004 |
Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase MP Blakeley, F Ruiz, R Cachau, I Hazemann, F Meilleur, A Mitschler, ... Proceedings of the National Academy of Sciences 105 (6), 1844-1848, 2008 | 97 | 2008 |
Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme M López, C Mayer, L Fernández-García, L Blasco, A Muras, FM Ruiz, ... PloS one 12 (3), e0174454, 2017 | 56 | 2017 |
N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in … D Solís, MJ Maté, M Lohr, JP Ribeiro, L López-Merino, S André, ... The International Journal of Biochemistry & Cell Biology 42 (6), 1019-1029, 2010 | 55 | 2010 |
Natural single amino acid polymorphism (F19Y) in human galectin‐8: detection of structural alterations and increased growth‐regulatory activity on tumor cells FM Ruiz, BA Scholz, E Buzamet, J Kopitz, S André, M Menéndez, ... The FEBS Journal 281 (5), 1446-1464, 2014 | 54 | 2014 |
The crystallographic structure of the aldose reductase–IDD552 complex shows direct proton donation from tyrosine 48 F Ruiz, I Hazemann, A Mitschler, A Joachimiak, T Schneider, M Karplus, ... Acta Crystallographica Section D: Biological Crystallography 60 (8), 1347-1354, 2004 | 45 | 2004 |
The structure of VgrG1 from Pseudomonas aeruginosa, the needle tip of the bacterial type VI secretion system M Spínola-Amilibia, I Davó-Siguero, FM Ruiz, E Santillana, FJ Medrano, ... Acta Crystallographica Section D: Structural Biology 72 (1), 22-33, 2016 | 41 | 2016 |
Structure-based discovery of novel non-nucleosidic DNA alkyltransferase inhibitors: virtual screening and in vitro and in vivo activities FM Ruiz, R Gil-Redondo, A Morreale, AR Ortiz, C Fábrega, J Bravo Journal of chemical information and modeling 48 (4), 844-854, 2008 | 38 | 2008 |
Crystal Structure of Hcp from Acinetobacter baumannii: A Component of the Type VI Secretion System FM Ruiz, E Santillana, M Spínola-Amilibia, E Torreira, E Culebras, ... PloS one 10 (6), e0129691, 2015 | 34 | 2015 |
Galectin-related protein: An integral member of the network of chicken galectins 1. From strong sequence conservation of the gene confined to vertebrates to biochemical … GG Caballero, A Flores-Ibarra, M Michalak, N Khasbiullina, NV Bovin, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (10), 2285-2297, 2016 | 30 | 2016 |
Development of a Novel Fluorescence Assay Based on the Use of the Thrombin‐Binding Aptamer for the Detection of O6‐Alkylguanine‐DNA Alkyltransferase Activity M Tintoré, A Aviñó, FM Ruiz, R Eritja, C Fàbrega Journal of nucleic acids 2010 (1), 632041, 2010 | 24 | 2010 |
Solving the RNA polymerase I structural puzzle M Moreno-Morcillo, NMI Taylor, T Gruene, P Legrand, UJ Rashid, ... Acta Crystallographica Section D: Biological Crystallography 70 (10), 2570-2582, 2014 | 23 | 2014 |
Members of the galectin network with deviations from the canonical sequence signature. 2. Galectin-related protein (GRP) JC Manning, GG Caballero, FM Ruiz, A Romero, H Kaltner, HJ Gabius Trends in Glycoscience and Glycotechnology 30 (172), SE11-SE20, 2018 | 21 | 2018 |
The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair R González-Corrochano, FM Ruiz, NMI Taylor, S Huecas, S Drakulic, ... Nucleic acids research 48 (17), 9943-9958, 2020 | 20 | 2020 |
Nucleotide‐induced folding of cell division protein FtsZ from Staphylococcus aureus S Huecas, AJ Canosa‐Valls, L Araújo‐Bazán, FM Ruiz, DV Laurents, ... The FEBS Journal 287 (18), 4048-4067, 2020 | 20 | 2020 |
Engineering protein assemblies with allosteric control via monomer fold-switching LA Campos, R Sharma, S Alvira, FM Ruiz, B Ibarra-Molero, M Sadqi, ... Nature Communications 10 (1), 5703, 2019 | 20 | 2019 |
Fine-tuning of prototype chicken galectins: structure of CG-2 and structure–activity correlations FM Ruiz, IS Fernández, L López-Merino, L Lagartera, H Kaltner, ... Acta Crystallographica Section D: Biological Crystallography 69 (9), 1665-1676, 2013 | 20 | 2013 |