Chemistry of MRI contrast agents: current challenges and new frontiers J Wahsner, EM Gale, A Rodríguez-Rodríguez, P Caravan Chemical reviews 119 (2), 957-1057, 2018 | 1328 | 2018 |
A manganese alternative to gadolinium for MRI contrast EM Gale, IP Atanasova, F Blasi, I Ay, P Caravan Journal of the American Chemical Society 137 (49), 15548-15557, 2015 | 345 | 2015 |
MR imaging probes: design and applications E Boros, EM Gale, P Caravan Dalton transactions 44 (11), 4804-4818, 2015 | 146 | 2015 |
Molecular magnetic resonance imaging using a redox-active iron complex H Wang, VC Jordan, IA Ramsay, M Sojoodi, BC Fuchs, KK Tanabe, ... Journal of the American Chemical Society 141 (14), 5916-5925, 2019 | 127 | 2019 |
A manganese-based alternative to gadolinium: contrast-enhanced MR angiography, excretion, pharmacokinetics, and metabolism EM Gale, HY Wey, I Ramsay, YF Yen, DE Sosnovik, P Caravan Radiology 286 (3), 865-872, 2018 | 118 | 2018 |
Direct Measurement of the Mn(II) Hydration State in Metal Complexes and Metalloproteins through 17O NMR Line Widths EM Gale, J Zhu, P Caravan Journal of the American Chemical Society 135 (49), 18600-18608, 2013 | 116 | 2013 |
Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging A Gupta, P Caravan, WS Price, C Platas-Iglesias, EM Gale Inorganic chemistry 59 (10), 6648-6678, 2020 | 113 | 2020 |
Manganese-based contrast agents for magnetic resonance imaging of liver tumors: Structure–activity relationships and lead candidate evaluation J Wang, H Wang, IA Ramsay, DJ Erstad, BC Fuchs, KK Tanabe, ... Journal of medicinal chemistry 61 (19), 8811-8824, 2018 | 98 | 2018 |
Structure–redox–relaxivity relationships for redox responsive manganese-based magnetic resonance imaging probes EM Gale, S Mukherjee, C Liu, GS Loving, P Caravan Inorganic Chemistry 53 (19), 10748-10761, 2014 | 98 | 2014 |
Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications L Dai, CM Jones, WTK Chan, TA Pham, X Ling, EM Gale, NJ Rotile, ... Nature communications 9 (1), 857, 2018 | 84 | 2018 |
A janus chelator enables biochemically responsive MRI contrast with exceptional dynamic range EM Gale, CM Jones, I Ramsay, CT Farrar, P Caravan Journal of the American Chemical Society 138 (49), 15861-15864, 2016 | 76 | 2016 |
Hexameric MnII Dendrimer as MRI Contrast Agent J Zhu, EM Gale, I Atanasova, TA Rietz, P Caravan Chemistry–A European Journal 20 (44), 14507-14513, 2014 | 69 | 2014 |
Synthetic analogues of nickel superoxide dismutase: a new role for nickel in biology EP Broering, PT Truong, EM Gale, TC Harrop Biochemistry 52 (1), 4-18, 2013 | 62 | 2013 |
Gadolinium-based contrast agents in pediatric magnetic resonance imaging EM Gale, P Caravan, AG Rao, RJ McDonald, M Winfeld, RJ Fleck, ... Pediatric radiology 47, 507-521, 2017 | 58 | 2017 |
Tumor contrast enhancement and whole-body elimination of the manganese-based magnetic resonance imaging contrast agent Mn-PyC3A DJ Erstad, IA Ramsay, VC Jordan, M Sojoodi, BC Fuchs, KK Tanabe, ... Investigative radiology 54 (11), 697-703, 2019 | 57 | 2019 |
Exploring the effects of H-bonding in synthetic analogues of nickel superoxide dismutase (Ni-SOD): experimental and theoretical implications for protection of the Ni− SCys bond EM Gale, BS Narendrapurapu, AC Simmonett, HF Schaefer III, TC Harrop Inorganic chemistry 49 (15), 7080-7096, 2010 | 56 | 2010 |
CM-101: type I collagen–targeted MR imaging probe for detection of liver fibrosis CT Farrar, EM Gale, R Kennan, I Ramsay, R Masia, G Arora, K Looby, ... Radiology 287 (2), 581-589, 2018 | 54 | 2018 |
Versatile Methodology Toward NiN2S2 Complexes as Nickel Superoxide Dismutase Models: Structure and Proton Affinity EM Gale, AK Patra, TC Harrop Inorganic chemistry 48 (13), 5620-5622, 2009 | 49 | 2009 |
Toward functional Ni-SOD biomimetics: achieving a structural/electronic correlation with redox dynamics EM Gale, AC Simmonett, J Telser, HF Schaefer III, TC Harrop Inorganic chemistry 50 (19), 9216-9218, 2011 | 47 | 2011 |
Dipeptide-based models of nickel superoxide dismutase: solvent effects highlight a critical role to Ni–S bonding and active site stabilization EM Gale, DM Cowart, RA Scott, TC Harrop Inorganic chemistry 50 (20), 10460-10471, 2011 | 38 | 2011 |