Data mining and machine learning techniques for the identification of mutagenicity inducing substructures and structure activity relationships of noncongeneric compounds C Helma, T Cramer, S Kramer, L De Raedt Journal of chemical information and computer sciences 44 (4), 1402-1411, 2004 | 352 | 2004 |
The predictive toxicology challenge 2000–2001 C Helma, RD King, S Kramer, A Srinivasan Bioinformatics 17 (1), 107-108, 2001 | 303 | 2001 |
Molecular feature mining in HIV data S Kramer, L De Raedt, C Helma Proceedings of the seventh ACM SIGKDD international conference on Knowledge …, 2001 | 288 | 2001 |
Genotoxic effects of heavy metals: comparative investigation with plant bioassays H Steinkellner, K Mun‐Sik, C Helma, S Ecker, TH Ma, O Horak, M Kundi, ... Environmental and molecular mutagenesis 31 (2), 183-191, 1998 | 257 | 1998 |
Statistical evaluation of the predictive toxicology challenge 2000–2001 H Toivonen, A Srinivasan, RD King, S Kramer, C Helma Bioinformatics 19 (10), 1183-1193, 2003 | 242 | 2003 |
A public domain image-analysis program for the single-cell gel-electrophoresis (comet) assay C Helma, M Uhl Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466 (1), 9-15, 2000 | 233 | 2000 |
Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells M Uhl, C Helma, S Knasmüller Mutation Research/Genetic Toxicology and Environmental Mutagenesis 468 (2 …, 2000 | 181 | 2000 |
lazar: a modular predictive toxicology framework A Maunz, M Gütlein, M Rautenberg, D Vorgrimmler, D Gebele, C Helma Frontiers in Pharmacology 4 (38), 2013 | 165 | 2013 |
Data quality in predictive toxicology: reproducibility of rodent carcinogenicity experiments. E Gottmann, S Kramer, B Pfahringer, C Helma Environmental health perspectives 109 (5), 509-514, 2001 | 147 | 2001 |
Collaborative development of predictive toxicology applications B Hardy, N Douglas, C Helma, M Rautenberg, N Jeliazkova, V Jeliazkov, ... Journal of cheminformatics 2, 1-29, 2010 | 137 | 2010 |
Lazy structure-activity relationships (lazar) for the prediction of rodent carcinogenicity and Salmonella mutagenicity C Helma Molecular diversity 10 (2), 147-158, 2006 | 137 | 2006 |
Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells M Uhl, C Helma, S Knasmüller Mutation Research/Genetic Toxicology and Environmental Mutagenesis 441 (2 …, 1999 | 134 | 1999 |
Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives E Benfenati, R Benigni, DM Demarini, C Helma, D Kirkland, TM Martin, ... Journal of Environmental Science and Health Part C 27 (2), 57-90, 2009 | 126 | 2009 |
The expanding role of predictive toxicology: an update on the (Q) SAR models for mutagens and carcinogens R Benigni, TI Netzeva, E Benfenati, C Bossa, R Franke, C Helma, ... Journal of Environmental Science and Health Part C 25 (1), 53-97, 2007 | 125 | 2007 |
Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo [4, 5-f] quinoline (IQ)-induced genotoxic effects and colonic … F Kassie, S Rabot, M Uhl, W Huber, HM Qin, C Helma, ... Carcinogenesis 23 (7), 1155-1161, 2002 | 122 | 2002 |
Prediction of adverse drug reactions using decision tree modeling F Hammann, H Gutmann, N Vogt, C Helma, J Drewe Clinical Pharmacology & Therapeutics 88 (1), 52-59, 2010 | 111 | 2010 |
Knowledge discovery and data mining in toxicology C Helma, E Gottmann, S Kramer Statistical methods in medical research 9 (4), 329-358, 2000 | 82 | 2000 |
Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment S Knasmüller, W Parzefall, C Helma, F Kassie, S Ecker, ... Critical reviews in toxicology 27 (5), 495-537, 1997 | 81 | 1997 |
Comparative evaluation of four bacterial assays for the detection of genotoxic effects in the dissolved water phases of aqueous matrices C Helma, V Mersch-Sundermann, VS Houk, U Glasbrenner, C Klein, ... Environmental science & technology 30 (3), 897-907, 1996 | 78 | 1996 |
Stochastic propositionalization of non-determinate background knowledge S Kramer, B Pfahringer, C Helma International Conference on Inductive Logic Programming, 80-94, 1998 | 68 | 1998 |