Novel insights into the function and dynamics of extracellular matrix in liver fibrosis MA Karsdal, T Manon-Jensen, F Genovese, JH Kristensen, MJ Nielsen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (10 …, 2015 | 244 | 2015 |
Collagen biology and non‐invasive biomarkers of liver fibrosis MA Karsdal, SJ Daniels, S Holm Nielsen, C Bager, DGK Rasmussen, ... Liver International 40 (4), 736-750, 2020 | 147 | 2020 |
Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls N Willumsen, CL Bager, DJ Leeming, V Smith, MA Karsdal, D Dornan, ... BMC cancer 13, 1-6, 2013 | 71 | 2013 |
Collagen degradation products measured in serum can separate ovarian and breast cancer patients from healthy controls: A preliminary study CL Bager, N Willumsen, DJ Leeming, V Smith, MA Karsdal, D Dornan, ... Cancer Biomarkers 15 (6), 783-788, 2015 | 70 | 2015 |
Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer N Willumsen, CL Bager, DJ Leeming, V Smith, C Christiansen, ... Cancer medicine 3 (5), 1136-1145, 2014 | 70 | 2014 |
Quantification of altered tissue turnover in a liquid biopsy: a proposed precision medicine tool to assess chronic inflammation and desmoplasia associated with a pro-cancerous … N Willumsen, LB Thomsen, CL Bager, C Jensen, MA Karsdal Cancer Immunology, Immunotherapy 67, 1-12, 2018 | 48 | 2018 |
Cathepsin-S degraded decorin are elevated in fibrotic lung disorders–development and biological validation of a new serum biomarker SN Kehlet, CL Bager, N Willumsen, B Dasgupta, C Brodmerkel, M Curran, ... BMC pulmonary medicine 17, 1-10, 2017 | 41 | 2017 |
Matrix metalloprotease generated fragments of type VI collagen have serum biomarker potential in cancer–A proof of concept study N Willumsen, C Bager, MA Karsdal Translational Oncology 12 (5), 693-698, 2019 | 38 | 2019 |
Nidogen-1 degraded by cathepsin S can be quantified in serum and is associated with non–small cell lung cancer N Willumsen, CL Bager, DJ Leeming, AC Bay-Jensen, MA Karsdal Neoplasia 19 (4), 271-278, 2017 | 30 | 2017 |
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis DJ Leeming, N Willumsen, JMB Sand, SH Nielsen, B Dasgupta, ... Biochemistry and Biophysics Reports 17, 38-43, 2019 | 26 | 2019 |
Quantification of fibronectin as a method to assess ex vivo extracellular matrix remodeling CL Bager, N Gudmann, N Willumsen, DJ Leeming, MA Karsdal, ... Biochemical and biophysical research communications 478 (2), 586-591, 2016 | 23 | 2016 |
Identification of pathological RA endotypes using blood-based biomarkers reflecting tissue metabolism. A retrospective and explorative analysis of two phase III RA studies JPM Blair, C Bager, A Platt, M Karsdal, AC Bay-Jensen PLoS One 14 (7), e0219980, 2019 | 21 | 2019 |
Matrix metalloproteinase mediated type I collagen degradation is an independent predictor of increased risk of acute myocardial infarction in postmenopausal women DM Bertelsen, JS Neergaard, CL Bager, SH Nielsen, NH Secher, ... Scientific reports 8 (1), 5371, 2018 | 21 | 2018 |
Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design CL Bager, M Karsdal, A Bihlet, C Thudium, I Byrjalsen, AC Bay-Jensen BMC Musculoskeletal Disorders 20, 1-6, 2019 | 16 | 2019 |
Remodeling of the tumor microenvironment predicts increased risk of cancer in postmenopausal women: the prospective epidemiologic risk factor (PERF I) study CL Bager, N Willumsen, SN Kehlet, HB Hansen, AC Bay-Jensen, ... Cancer Epidemiology, Biomarkers & Prevention 25 (9), 1348-1355, 2016 | 15 | 2016 |
Cancer risk in relation to body fat distribution, evaluated by DXA-scans, in postmenopausal women–the Prospective Epidemiological Risk Factor (PERF) study LM Staunstrup, HB Nielsen, BK Pedersen, M Karsdal, JPM Blair, ... Scientific Reports 9 (1), 5379, 2019 | 14 | 2019 |
Bone and soft tissue turnover in relation to all-cause mortality in postmenopausal women CL Bager, N Willumsen, C Christiansen, AC Bay-Jensen, HB Nielsen, ... The Journals of Gerontology: Series A 74 (7), 1098-1104, 2019 | 13 | 2019 |
Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of … N Willumsen, CL Bager, SN Kehlet, K Dragsbaek, JS Neergaard, ... Oncotarget 8 (32), 52501, 2017 | 13 | 2017 |
Extracellular matrix (ECM) circulating peptide biomarkers as potential predictors of survival in patients (pts) with untreated metastatic pancreatic ductal adenocarcinoma (mPDA … S Wang, N Willumsen, C Bager, MA Karsdal, D Chondros, D Taverna Journal of Clinical Oncology 36 (15_suppl), 12030-12030, 2018 | 12 | 2018 |
Atrial fibrillation is associated with lean body mass in postmenopausal women MS Worm, CL Bager, JPM Blair, NH Secher, BJ Riis, C Christiansen, ... Scientific Reports 10 (1), 573, 2020 | 8 | 2020 |