Ajaybabu Pobbati
Ajaybabu Pobbati
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N-to C-terminal SNARE complex assembly promotes rapid membrane fusion
AV Pobbati, A Stein, D Fasshauer
Science 313 (5787), 673-676, 2006
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
SW Chan, CJ Lim, YF Chong, AV Pobbati, C Huang, W Hong
Journal of Biological Chemistry 286 (9), 7018-7026, 2011
Emerging roles of TEAD transcription factors and its coactivators in cancers
AV Pobbati, W Hong
Cancer biology & therapy 14 (5), 390-398, 2013
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24
S Ghazi-Tabatabai, S Saksena, JM Short, AV Pobbati, DB Veprintsev, ...
Structure 16 (9), 1345-1356, 2008
Agrin as a mechanotransduction signal regulating YAP through the Hippo pathway
S Chakraborty, K Njah, AV Pobbati, YB Lim, A Raju, M Lakshmanan, ...
Cell reports 18 (10), 2464-2479, 2017
Structural and functional similarity between the Vgll1-TEAD and the YAP-TEAD complexes
AV Pobbati, SW Chan, I Lee, H Song, W Hong
Structure 20 (7), 1135-1140, 2012
Structural Basis for the Inhibitory Role of Tomosyn in Exocytosis*♦
AV Pobbati, A Razeto, M Böddener, S Becker, D Fasshauer
Journal of Biological Chemistry 279 (45), 47192-47200, 2004
Targeting the central pocket in human transcription factor TEAD as a potential cancer therapeutic strategy
AV Pobbati, X Han, AW Hung, S Weiguang, N Huda, GY Chen, CB Kang, ...
Structure 23 (11), 2076-2086, 2015
A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy
AV Pobbati, W Hong
Theranostics 10 (8), 3622, 2020
VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
N Figeac, AD Mohamed, C Sun, M Schönfelder, D Matallanas, ...
Journal of cell science 132 (13), jcs225946, 2019
Evolution and assembly of ESCRTs
S Ghazi-Tabatabai, T Obita, AV Pobbati, O Perisic, RY Samson, SD Bell, ...
Biochemical Society Transactions 37 (1), 151-155, 2009
A role of agrin in maintaining the stability of vascular endothelial growth factor receptor-2 during tumor angiogenesis
K Njah, S Chakraborty, B Qiu, S Arumugam, A Raju, AV Pobbati, ...
Cell reports 28 (4), 949-965. e7, 2019
Structural and ligand-binding analysis of the YAP-binding domain of transcription factor TEAD4
Y Li, S Liu, EY Ng, R Li, A Poulsen, J Hill, AV Pobbati, AW Hung, W Hong, ...
Biochemical Journal 475 (12), 2043-2055, 2018
Identification of quinolinols as activators of TEAD-dependent transcription
AV Pobbati, T Mejuch, S Chakraborty, H Karatas, SR Bharath, SM Guéret, ...
ACS Chemical Biology 14 (12), 2909-2921, 2019
Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex
AV Pobbati, BP Rubin
Molecules 25 (24), 6001, 2020
A protein tertiary structure mimetic modulator of the Hippo signalling pathway
H Adihou, R Gopalakrishnan, T Förster, SM Guéret, R Gasper, ...
Nature communications 11 (1), 1-10, 2020
Discovery of covalent inhibitors targeting the transcriptional enhanced associate domain central pocket
H Karatas, M Akbarzadeh, H Adihou, G Hahne, AV Pobbati, E Yihui Ng, ...
Journal of medicinal chemistry 63 (20), 11972-11989, 2020
WWTR1 (TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis
CN Seavey, AV Pobbati, A Hallett, S Ma, JP Reynolds, R Kanai, JM Lamar, ...
Genes & development 35 (7-8), 512-527, 2021
Transglutaminase 2 Is a Direct Target Gene of YAP/TAZ
CY Liu, AV Pobbati, Z Huang, L Cui, W Hong
Cancer Research 77 (17), 4734-4735, 2017
Design, Synthesis and Evaluation of a Series of 1, 5‐Diaryl‐1, 2, 3‐triazole‐4‐carbohydrazones as Inhibitors of the YAP‐TAZ/TEAD Complex
F Gibault, M Sturbaut, M Coevoet, M Pugnière, A Burtscher, F Allemand, ...
ChemMedChem 16 (18), 2823-2844, 2021
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