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Grace Tiao
Grace Tiao
Associate Director, Computational Genomics; Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Analysis of protein-coding genetic variation in 60,706 humans
M Lek, KJ Karczewski, EV Minikel, KE Samocha, E Banks, T Fennell, ...
Nature 536 (7616), 285-291, 2016
101682016
The mutational constraint spectrum quantified from variation in 141,456 humans
KJ Karczewski, LC Francioli, G Tiao, BB Cummings, J Alföldi, Q Wang, ...
Nature 581 (7809), 434-443, 2020
70172020
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1666*2020
Integrated genomic characterization of pancreatic ductal adenocarcinoma
BJ Raphael, RH Hruban, AJ Aguirre, RA Moffitt, JJ Yeh, C Stewart, ...
Cancer cell 32 (2), 185-203. e13, 2017
15222017
Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes
KJ Karczewski, LC Francioli, G Tiao, BB Cummings, J Alföldi, Q Wang, ...
biorxiv, 531210, 2019
11602019
A structural variation reference for medical and population genetics
RL Collins, H Brand, KJ Karczewski, X Zhao, J Alföldi, LC Francioli, ...
Nature 581 (7809), 444-451, 2020
6992020
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
SA Shukla, MS Rooney, M Rajasagi, G Tiao, PM Dixon, MS Lawrence, ...
Nature biotechnology 33 (11), 1152-1158, 2015
6772015
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
5022020
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
P Polak, J Kim, LZ Braunstein, R Karlic, NJ Haradhavala, G Tiao, ...
Nature genetics 49 (10), 1476-1486, 2017
4882017
Rare coding variants in ten genes confer substantial risk for schizophrenia
T Singh, T Poterba, D Curtis, H Akil, M Al Eissa, JD Barchas, N Bass, ...
Nature 604 (7906), 509-516, 2022
4082022
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
J Kim, KW Mouw, P Polak, LZ Braunstein, A Kamburov, G Tiao, ...
Nature genetics 48 (6), 600-606, 2016
4072016
Recurrent and functional regulatory mutations in breast cancer
E Rheinbay, P Parasuraman, J Grimsby, G Tiao, JM Engreitz, J Kim, ...
Nature 547 (7661), 55-60, 2017
3232017
Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution
S Kasar, J Kim, R Improgo, G Tiao, P Polak, N Haradhvala, MS Lawrence, ...
Nature communications 6 (1), 8866, 2015
2712015
A genome-wide mutational constraint map quantified from variation in 76,156 human genomes
S Chen, LC Francioli, JK Goodrich, RL Collins, M Kanai, Q Wang, J Alföldi, ...
BioRxiv, 2022.03. 20.485034, 2022
1592022
Alfö ldi J, Wang Q, et al. The mutational constraint spectrum quantified from variation in 141,456 humans
KJ Karczewski, LC Francioli, G Tiao, BB Cummings
Nature 581 (7809), 434-43, 2020
1412020
Landscape of genomic alterations in pituitary adenomas
WL Bi, P Horowitz, NF Greenwald, M Abedalthagafi, PK Agarwalla, ...
Clinical Cancer Research 23 (7), 1841-1851, 2017
1222017
Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes
KJ Karczewski, M Solomonson, KR Chao, JK Goodrich, G Tiao, W Lu, ...
Cell Genomics 2 (9), 2022
1042022
Insights into the gyrification of developing ferret brain by magnetic resonance imaging
J Neal, M Takahashi, M Silva, G Tiao, CA Walsh, VL Sheen
Journal of anatomy 210 (1), 66-77, 2007
922007
An open resource of structural variation for medical and population genetics
RL Collins, H Brand, KJ Karczewski, X Zhao, J Alföldi, AV Khera, ...
BioRxiv, 578674, 2019
832019
Rapid microbial response to the presence of an ancient relic in the Antarctic Dry Valleys
G Tiao, CK Lee, IR McDonald, DA Cowan, SC Cary
Nature Communications 3 (1), 660, 2012
762012
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Articles 1–20