Phospholipase A2—a structural review RK Arni, RJ Ward Toxicon 34 (8), 827-841, 1996 | 535 | 1996 |
Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom RK Arni, RJ Ward, JM Gutiérrez, A Tulinsky Acta Crystallographica Section D: Biological Crystallography 51 (3), 311-317, 1995 | 150 | 1995 |
Structural basis for glucose tolerance in GH1 β-glucosidases PO de Giuseppe, TACB Souza, FHM Souza, LM Zanphorlin, CB Machado, ... Acta Crystallographica Section D: Biological Crystallography 70 (6), 1631-1639, 2014 | 144 | 2014 |
Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis RJ Ward, L Chioato, AHC de OLIVEIRA, R Ruller, JM Sá Biochemical Journal 362 (1), 89-96, 2002 | 134 | 2002 |
Dissociation of enzymatic and pharmacological properties of piratoxins-I and-III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom AM Soares, SH Andrião-Escarso, RK Bortoleto, L Rodrigues-Simioni, ... Archives of Biochemistry and Biophysics 387 (2), 188-196, 2001 | 126 | 2001 |
Glucose tolerant and glucose stimulated β-glucosidases–a review JCS Salgado, LP Meleiro, S Carli, RJ Ward Bioresource technology 267, 704-713, 2018 | 118 | 2018 |
Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in bothropstoxin I, a dimeric Lys49‐phospholipase A2 homologue MT da Silva Giotto, RC Garratt, G Oliva, YP Mascarenhas, JR Giglio, ... Proteins: Structure, Function, and Bioinformatics 30 (4), 442-454, 1998 | 117 | 1998 |
Mapping structural determinants of biological activities in snake venom phospholipases A2 by sequence analysis and site directed mutagenesis L Chioato, RJ Ward Toxicon 42 (8), 869-883, 2003 | 112 | 2003 |
Isolation, purification, and physicochemical characterization of a D-galactose-binding lectin from seeds of Erythrina speciosa EHE Konozy, ES Bernardes, C Rosa, V Faca, LJ Greene, RJ Ward Archives of Biochemistry and Biophysics 410 (2), 222-229, 2003 | 105 | 2003 |
Dissecting structure–function–stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168 CR Santos, JH Paiva, ML Sforca, JL Neves, RZ Navarro, J Cota, PK Akao, ... Biochemical Journal 441 (1), 95-104, 2012 | 103 | 2012 |
Thermostable variants of the recombinant xylanase a from Bacillus subtilis produced by directed evolution show reduced heat capacity changes R Ruller, L Deliberto, TL Ferreira, RJ Ward Proteins: Structure, Function, and Bioinformatics 70 (4), 1280-1293, 2008 | 92 | 2008 |
Distinct sites for myotoxic and membrane-damaging activities in the C-terminal region of a Lys49-phospholipase A2 L Chioato, AHC OLIVEIRA, R Ruller, JM Sá, RJ Ward Biochemical journal 366 (3), 971-976, 2002 | 92 | 2002 |
A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change ALB Ambrosio, MC Nonato, HSS de Araújo, R Arni, RJ Ward, CL Ownby, ... Journal of Biological Chemistry 280 (8), 7326-7335, 2005 | 88 | 2005 |
Structural and functional analysis of BmjMIP, a phospholipase A2 myotoxin inhibitor protein from Bothrops moojeni snake plasma AM Soares, S Marcussi, RG Stábeli, SC França, JR Giglio, RJ Ward, ... Biochemical and biophysical research communications 302 (2), 193-200, 2003 | 88 | 2003 |
Histidine residues near the N terminus of staphylococcal alpha-toxin as reporters of regions that are critical for oligomerization and pore formation R Jursch, A Hildebrand, G Hobom, J Tranum-Jensen, R Ward, M Kehoe, ... Infection and immunity 62 (6), 2249-2256, 1994 | 88 | 1994 |
Engineering the pattern of protein glycosylation modulates the thermostability of a GH11 xylanase R Fonseca-Maldonado, DS Vieira, JS Alponti, E Bonneil, P Thibault, ... Journal of biological chemistry 288 (35), 25522-25534, 2013 | 87 | 2013 |
Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening ME Guazzaroni, R Silva‐Rocha, RJ Ward Microbial Biotechnology 8 (1), 52-64, 2015 | 82 | 2015 |
Biochemical and structural characterization of a β-1, 3–1, 4-glucanase from Bacillus subtilis 168 GP Furtado, LF Ribeiro, CR Santos, CC Tonoli, AR De Souza, RR Oliveira, ... Process Biochemistry 46 (5), 1202-1206, 2011 | 80 | 2011 |
Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis L Chioato, EA Aragão, TL Ferreira, AI de Medeiros, LH Faccioli, RJ Ward Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (5), 1247-1257, 2007 | 79 | 2007 |
A novel thermostable xylanase GH10 from Malbranchea pulchella expressed in Aspergillus nidulans with potential applications in biotechnology LFC Ribeiro, RC De Lucas, GL Vitcosque, LF Ribeiro, RJ Ward, MV Rubio, ... Biotechnology for biofuels 7, 1-11, 2014 | 72 | 2014 |