A tris (2-carboxyethyl) phosphine (TCEP) related cleavage on cysteine-containing proteins P Liu, BW O’mara, BM Warrack, W Wu, Y Huang, Y Zhang, R Zhao, M Lin, ... Journal of the American Society for Mass Spectrometry 21, 837-844, 2010 | 79 | 2010 |
Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling H Zhang, W Wu, Y Du, SJ Santos, SE Conrad, JT Watson, ... Journal of Biological Chemistry 279 (19), 19457-19463, 2004 | 76 | 2004 |
Characterization of glycosylation sites for a recombinant IgG1 monoclonal antibody and a CTLA4-Ig fusion protein by liquid chromatography–mass spectrometry peptide mapping J Bongers, J Devincentis, J Fu, P Huang, DH Kirkley, K Leister, P Liu, ... Journal of Chromatography A 1218 (45), 8140-8149, 2011 | 55 | 2011 |
Investigation of monoclonal antibody fragmentation artifacts in non-reducing SDS-PAGE ZC Zhu, Y Chen, MS Ackerman, B Wang, W Wu, B Li, L Obenauer-Kutner, ... Journal of pharmaceutical and biomedical analysis 83, 89-95, 2013 | 40 | 2013 |
New peak detection performance metrics from the MAM consortium interlaboratory study T Mouchahoir, JE Schiel, R Rogers, A Heckert, BJ Place, A Ammerman, ... Journal of the American Society for Mass Spectrometry 32 (4), 913-928, 2021 | 34 | 2021 |
Enhancing host-cell protein detection in protein therapeutics using HILIC enrichment and proteomic analysis Q Wang, TR Slaney, W Wu, R Ludwig, L Tao, A Leone Analytical Chemistry 92 (15), 10327-10335, 2020 | 31 | 2020 |
Automated data interpretation based on the concept of “negative signature mass” for mass-mapping disulfide structures of cystinyl proteins J Qi, W Wu, CR Borges, D Hang, M Rupp, E Torng, JT Watson Journal of the American Society for Mass Spectrometry 14 (9), 1032-1038, 2003 | 27 | 2003 |
Subunit mass analysis for monitoring multiple attributes of monoclonal antibodies P Liu, X Zhu, W Wu, R Ludwig, H Song, R Li, J Zhou, L Tao, AM Leone Rapid Communications in Mass Spectrometry 33 (1), 31-40, 2019 | 26 | 2019 |
Investigation of color in a fusion protein using advanced analytical techniques: delineating contributions from oxidation products and process related impurities H Song, J Xu, M Jin, C Huang, J Bongers, H Bai, W Wu, R Ludwig, Z Li, ... Pharmaceutical research 33, 932-941, 2016 | 25 | 2016 |
‘Signature Sets', Minimal Fragment Sets for Identifying Protein Disulfide Structures with Cyanylation-Based Mass Mapping Methodology W Wu, W Huang, J Qi, YT Chou, E Torng, JT Watson Journal of proteome research 3 (4), 770-777, 2004 | 14 | 2004 |
Algorithm-assisted elucidation of disulfide structure: application of the negative signature mass algorithm to mass-mapping the disulfide structure of the 12-cysteine … CR Borges, J Qi, W Wu, E Torng, AP Hinck, JT Watson Analytical biochemistry 329 (1), 91-103, 2004 | 12 | 2004 |
Characterization of impurities and degradants in protein therapeutics by mass spectrometry L Tao, M Ackerman, W Wu, P Liu, R Russell Characterization of Impurities and Degradants Using Mass Spectrometry, 391-426, 2011 | 8 | 2011 |
Attribute analytics performance metrics from the MAM consortium interlaboratory study T Mouchahoir, JE Schiel, R Rogers, A Heckert, BJ Place, A Ammerman, ... Journal of the American Society for Mass Spectrometry 33 (9), 1659-1677, 2022 | 5 | 2022 |
Characterization of S‐thiolation on secreted proteins from E. coli by mass spectrometry P Liu, MA Tarnowski, BW O'Mara, W Wu, H Zhang, JK Tamura, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009 | 5 | 2009 |
Characterization of protein therapeutics by mass spectrometry W Wu, H Song, T Slaney, R Ludwig, L Tao, T Das Protein Analysis Using Mass Spectrometry: Accelerating Protein …, 2017 | 3 | 2017 |
Codon-Directed Determination of the Biological Causes of Sequence Variants in Therapeutic Proteins T Jiang, H Song, TR Slaney, W Wu, E Langsdorf, G Gupta, R Ludwig, ... Analytical chemistry 89 (23), 12749-12755, 2017 | 2 | 2017 |
Molecular Variants Characterization in Protein Therapeutics Development R Ludwig, J Bongers, L Tao, Y Huang, J Fu, W Wu, P Liu, H Song, ... Characterization of Protein Therapeutics using Mass Spectrometry, 207-277, 2013 | 2 | 2013 |
Mass spectrometric evidence for an alternate disulfide bond in chloroplast fructose bisphosphatase W Wu, JT Watson, FJ Stevens, R Yousefzai, LE Anderson Photosynthesis Research 79, 189-200, 2004 | 2 | 2004 |
Applications and computational considerations of the cyanylation-based disulfide mapping methodology for cystinyl proteins W Wu Michigan State University, 2003 | 1 | 2003 |
Ceramic hydroxyapatite chromatography plays a critical role in bispecific antibody purification process for impurity removal JA Waller, J Zheng, R Dyer, T Slaney, W Wu, L Tao, S Ghose Antibody Therapeutics 6 (1), 30-37, 2023 | | 2023 |