Eric V. Shusta
Eric V. Shusta
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Cited by
Cited by
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
ES Lippmann, SM Azarin, JE Kay, RA Nessler, HK Wilson, A Al-Ahmad, ...
Nature biotechnology 30 (8), 783-791, 2012
In vitro models of the blood–brain barrier: an overview of commonly used brain endothelial cell culture models and guidelines for their use
HC Helms, NJ Abbott, M Burek, R Cecchelli, PO Couraud, MA Deli, ...
Journal of Cerebral Blood Flow & Metabolism 36 (5), 862-890, 2016
Blood–brain barrier transport of therapeutics via receptor-mediation
AR Jones, EV Shusta
Pharmaceutical research 24, 1759-1771, 2007
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
ES Lippmann, A Al-Ahmad, SM Azarin, SP Palecek, EV Shusta
Scientific reports 4 (1), 4160, 2014
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland, R Hasselkus, R Mannix, ...
Nature communications 10 (1), 2621, 2019
In vitro evolution of a T cell receptor with high affinity for peptide/MHC
PD Holler, PO Holman, EV Shusta, S O'Herrin, KD Wittrup, DM Kranz
Proceedings of the National Academy of Sciences 97 (10), 5387-5392, 2000
Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier
JM Lajoie, EV Shusta
Annual review of pharmacology and toxicology 55, 613-631, 2015
Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments
EV Shusta, RT Raines, A Plückthun, KD Wittrup
Nature biotechnology 16 (8), 773-777, 1998
Efficient differentiation of human pluripotent stem cells to endothelial progenitors via small-molecule activation of WNT signaling
X Lian, X Bao, A Al-Ahmad, J Liu, Y Wu, W Dong, KK Dunn, EV Shusta, ...
Stem cell reports 3 (5), 804-816, 2014
Directed evolution of a stable scaffold for T-cell receptor engineering
EV Shusta, PD Holler, MC Kieke, DM Kranz, KD Wittrup
Nature biotechnology 18 (7), 754-759, 2000
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency
EV Shusta, MC Kieke, E Parke, DM Kranz, KD Wittrup
Journal of molecular biology 292 (5), 949-956, 1999
Selection of functional T cell receptor mutants from a yeast surface-display library
MC Kieke, EV Shusta, ET Boder, L Teyton, KD Wittrup, DM Kranz
Proceedings of the National Academy of Sciences 96 (10), 5651-5656, 1999
A decade of yeast surface display technology: where are we now?
EV Shusta, LR Pepper, YK Cho, ET Boder
Combinatorial chemistry & high throughput screening 11 (2), 127-134, 2008
An isogenic blood–brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells
SG Canfield, MJ Stebbins, BS Morales, SW Asai, GD Vatine, ...
Journal of neurochemistry 140 (6), 874-888, 2017
Yeast cell surface display of proteins and uses thereof
MC Kieke, KD Wittrup, ET Boder, DM Kranz, E Shusta
US Patent 6,300,065, 2001
Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells
T Qian, SE Maguire, SG Canfield, X Bao, WR Olson, EV Shusta, ...
Science advances 3 (11), e1701679, 2017
Modeling psychomotor retardation using iPSCs from MCT8-deficient patients indicates a prominent role for the blood-brain barrier
GD Vatine, A Al-Ahmad, BK Barriga, S Svendsen, A Salim, L Garcia, ...
Cell stem cell 20 (6), 831-843. e5, 2017
Puromycin‐purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction
AR Calabria, C Weidenfeller, AR Jones, HE De Vries, EV Shusta
Journal of neurochemistry 97 (4), 922-933, 2006
Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
MJ Stebbins, BD Gastfriend, SG Canfield, MS Lee, D Richards, ...
Science advances 5 (3), eaau7375, 2019
Differentiating embryonic neural progenitor cells induce blood–brain barrier properties
C Weidenfeller, CN Svendsen, EV Shusta
Journal of neurochemistry 101 (2), 555-565, 2007
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