MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis KV Floros, JY Cai, S Jacob, R Kurupi, CK Fairchild, M Shende, CM Coon, ... Cancer research 81 (7), 1896-1908, 2021 | 102 | 2021 |
Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis L Xue, JY Cai, J Ma, Z Huang, MX Guo, LZ Fu, YB Shi, WX Li BMC genomics 14, 1-17, 2013 | 83 | 2013 |
Gene expression atlas for human embryogenesis H Yi, L Xue, MX Guo, J Ma, Y Zeng, W Wang, JY Cai, HM Hu, HB Shu, ... The FASEB Journal 24 (9), 3341, 2010 | 75 | 2010 |
The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signaling W Wang, M Guo, L Hu, J Cai, Y Zeng, J Luo, Z Shu, W Li, Z Huang Journal of Biological Chemistry 287 (51), 42856-42866, 2012 | 34 | 2012 |
Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1 W Wang, J Cai, Y Wu, L Hu, Z Chen, J Hu, Z Chen, W Li, M Guo, Z Huang Cellular and molecular life sciences 70, 3947-3958, 2013 | 22 | 2013 |
Sorting nexin 5 controls head and neck squamous cell carcinoma progression by modulating FBW7 J Cai, M Sun, B Hu, B Windle, X Ge, G Li, Y Sun Journal of Cancer 10 (13), 2942, 2019 | 18 | 2019 |
ZNF300 knockdown inhibits forced megakaryocytic differentiation by phorbol and erythrocytic differentiation by arabinofuranosyl cytidine in K562 cells J Cai, R Gong, F Yan, C Yu, L Liu, W Wang, Y Lin, M Guo, W Li, Z Huang PLoS One 9 (12), e114768, 2014 | 18 | 2014 |
CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing Z Liu, W Liu, W Wang, Y Ma, Y Wang, DL Drum, J Cai, H Blevins, E Lee, ... Proceedings of the National Academy of Sciences 120 (39), e2302878120, 2023 | 17 | 2023 |
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition J Cai, S Jacob, R Kurupi, KM Dalton, C Coon, P Greninger, RK Egan, ... Cell reports 40 (4), 2022 | 17 | 2022 |
EGFR tyrosine kinase inhibitors differentially affect autophagy in head and neck squamous cell carcinoma Jinyang Cai , Sun Ming, Ge Xin, Sun Yue Biochem Biophys Res Commun 486 (4), 1027-1033, 2017 | 17 | 2017 |
Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins W Wang, J Cai, Y Lin, Z Liu, Q Ren, L Hu, Z Huang, M Guo, W Li PloS one 9 (3), e92155, 2014 | 15 | 2014 |
Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma KM Dalton, K Krytska, TL Lochmann, R Sano, C Casey, A D'Aulerio, ... Molecular cancer therapeutics 20 (8), 1400-1411, 2021 | 14 | 2021 |
Aberrant expression of ZNF268 alters the growth and migration of ovarian cancer cells L Hu, W Wang, J Cai, J Luo, Y Huang, S Xiong, W Li, M Guo Oncology Letters 6 (1), 49-54, 2013 | 14 | 2013 |
Scavenger receptor a is a major homeostatic regulator that restrains drug-induced liver injury C Guo, W Liu, Z Liu, J Cai, X Yu, H Wang, X Li, D Zuo, X Jiang, B Zhang, ... Hepatology 78 (1), 45-57, 2023 | 10 | 2023 |
Type I γ phosphatidylinositol phosphate 5-kinase i5 controls the ubiquitination and degradation of the tumor suppressor mitogen-inducible gene 6 M Sun, J Cai, RA Anderson, Y Sun Journal of Biological Chemistry 291 (41), 21461-21473, 2016 | 9 | 2016 |
Pulchinenosides from Pulsatilla Chinensis increase P‐glycoprotein activity and induce P‐glycoprotein expression Y Liu, L Zhang, S Wei, J Cai, Z Zang, M Wang, D Su, PM Gerk Evidence‐Based Complementary and Alternative Medicine 2020 (1), 4861719, 2020 | 7 | 2020 |
Pharmacologic inhibition of SHP2 blocks both PI3K and MEK signaling in low-epiregulin HNSCC via GAB1 R Kurupi, KV Floros, S Jacob, AT Chawla, J Cai, B Hu, M Puchalapalli, ... Cancer research communications 2 (9), 1061-1074, 2022 | 6 | 2022 |
Neutrophils exacerbate acetaminophen-induced liver injury by producing cytotoxic interferon-γ H Wu, C Guo, Z Liu, J Cai, C Wang, H Yi, A Sanyal, P Puri, H Zhou, ... International Immunopharmacology 123, 110734, 2023 | 3 | 2023 |
Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models S Jacob, TH Turner, J Cai, KV Floros, AK Yu, CM Coon, R Khatri, ... PNAS nexus 1 (5), pgac232, 2022 | 3 | 2022 |
Characterization of a small molecule inhibitor of the NLRP3 inflammasome and its potential use for acute lung injury Y Xu, S Biby, C Guo, Z Liu, J Cai, XY Wang, S Zhang Bioorganic Chemistry, 107562, 2024 | 2 | 2024 |