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Jan Christoph Koch
Jan Christoph Koch
University Medicine Göttingen, Dept. of Neurology
Verified email at med.uni-goettingen.de - Homepage
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13491*2021
Mechanisms of acute axonal degeneration in the optic nerve in vivo
J Knöferle, JC Koch, T Ostendorf, U Michel, V Planchamp, P Vutova, ...
Proceedings of the National Academy of Sciences 107 (13), 6064-6069, 2010
3182010
Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study
T Hagenacker, CD Wurster, R Günther, O Schreiber-Katz, A Osmanovic, ...
The Lancet Neurology 19 (4), 317-325, 2020
2452020
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease
L Tönges, T Frank, L Tatenhorst, KA Saal, JC Koch, ÉM Szegő, M Bähr, ...
Brain 135 (11), 3355-3370, 2012
1952012
Hot-spot KIF5A mutations cause familial ALS
D Brenner, R Yilmaz, K Müller, T Grehl, S Petri, T Meyer, J Grosskreutz, ...
Brain 141 (3), 688-697, 2018
1922018
ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS
JC Koch, L Tönges, E Barski, U Michel, M Bähr, P Lingor
Cell death & disease 5 (5), e1225-e1225, 2014
1882014
ROCK inhibition in models of neurodegeneration and its potential for clinical translation
JC Koch, L Tatenhorst, AE Roser, KA Saal, L Tönges, P Lingor
Pharmacology & Therapeutics 189, 1-21, 2018
1832018
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation
TR Doeppner, M Doehring, E Bretschneider, A Zechariah, B Kaltwasser, ...
Acta neuropathologica 126, 251-265, 2013
1782013
Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells
LMA Oliveira, LJ Falomir-Lockhart, MG Botelho, KH Lin, P Wales, JC Koch, ...
Cell death & disease 6 (11), e1994-e1994, 2015
1652015
Axonal degeneration as a therapeutic target in the CNS
P Lingor, JC Koch, L Tönges, M Bähr
Cell and tissue research 349, 289-311, 2012
1472012
Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons
JC Koch, F Bitow, J Haack, Z d'Hedouville, JN Zhang, L Tönges, U Michel, ...
Cell death & disease 6 (7), e1811-e1811, 2015
1432015
Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease
L Tatenhorst, K Eckermann, V Dambeck, L Fonseca-Ornelas, H Walle, ...
Acta neuropathologica communications 4, 1-17, 2016
1352016
Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis
L Tönges, R Günther, M Suhr, J Jansen, A Balck, KA Saal, E Barski, ...
Glia 62 (2), 217-232, 2014
1252014
ROCKing regeneration: Rho kinase inhibition as molecular target for neurorestoration
L Tönges, JC Koch, M Bähr, P Lingor
Frontiers in molecular neuroscience 4, 39, 2011
1132011
Safety and effectiveness of long-term intravenous administration of edaravone for treatment of patients with amyotrophic lateral sclerosis
S Witzel, A Maier, R Steinbach, J Grosskreutz, JC Koch, A Sarikidi, S Petri, ...
JAMA neurology 79 (2), 121-130, 2022
972022
Loss‐of‐Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities
D Steel, M Zech, C Zhao, KES Barwick, D Burke, D Demailly, KR Kumar, ...
Annals of neurology 88 (5), 867-877, 2020
802020
Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo
L Tönges, T Ostendorf, F Lamballe, M Genestine, R Dono, JC Koch, ...
Journal of neurochemistry 117 (5), 892-903, 2011
762011
AAV. shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
KA Saal, JC Koch, L Tatenhorst, ÉM Szegő, VT Ribas, U Michel, M Bähr, ...
Neurobiology of disease 73, 150-162, 2015
722015
Prognostic factors in ALS: a comparison between Germany and China
J Dorst, L Chen, A Rosenbohm, J Dreyhaupt, A Hübers, J Schuster, ...
Journal of neurology 266, 1516-1525, 2019
672019
Managing the crisis: How COVID‐19 demands interact with agile project management in predicting employee exhaustion
J Koch, CC Schermuly
British Journal of Management 32 (4), 1265-1283, 2021
632021
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