Tomonori Hosoya
Tomonori Hosoya
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Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema
Y Ishii, K Itoh, Y Morishima, T Kimura, T Kiwamoto, T IIzuka, AE Hegab, ...
The Journal of Immunology 175 (10), 6968-6975, 2005
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells
T Hosoya, A Maruyama, MI Kang, Y Kawatani, T Shibata, K Uchida, K Itoh, ...
Journal of Biological Chemistry 280 (29), 27244-27250, 2005
BRG1 Interacts with Nrf2 To Selectively Mediate HO-1 Induction in Response to Oxidative Stress
J Zhang, T Ohta, A Maruyama, T Hosoya, K Nishikawa, JM Maher, ...
Molecular and cellular biology 26 (21), 7942-7952, 2006
Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages
N Harada, M Kanayama, A Maruyama, A Yoshida, K Tazumi, T Hosoya, ...
Archives of biochemistry and biophysics 508 (1), 101-109, 2011
Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse
T Moriguchi, H Motohashi, T Hosoya, O Nakajima, S Takahashi, S Ohsako, ...
Proceedings of the National Academy of Sciences 100 (10), 5652-5657, 2003
Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions
M Tauchi, A Hida, T Negishi, F Katsuoka, S Noda, J Mimura, T Hosoya, ...
Molecular and cellular biology, 2005
GATA-3 is required for early T lineage progenitor development
T Hosoya, T Kuroha, T Moriguchi, D Cummings, I Maillard, KC Lim, ...
Journal of Experimental Medicine 206 (13), 2987-3000, 2009
From the cradle to the grave: activities of GATA‐3 throughout T‐cell development and differentiation
T Hosoya, I Maillard, JD Engel
Immunological reviews 238 (1), 110-125, 2010
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning
KC Lim, T Hosoya, W Brandt, CJ Ku, S Hosoya-Ohmura, SA Camper, ...
The Journal of clinical investigation 122 (10), 3705-3717, 2012
Defective development of secretory neurones in the hypothalamus of Arnt2‐knockout mice
T Hosoya, Y Oda, S Takahashi, M Morita, S Kawauchi, M Ema, ...
Genes to Cells 6 (4), 361-374, 2001
Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes
J Zhang, T Hosoya, A Maruyama, K Nishikawa, JM Maher, T Ohta, ...
Biochemical Journal 404 (3), 459-466, 2007
Mild Impairment of Learning and Memory in Mice Overexpressing the mSim2 Gene Located on Chromosome 16: An Animal Model of Down's Syndrome
M Ema, S Ikegami, T Hosoya, J Mimura, H Ohtani, K Nakao, K Inokuchi, ...
Human molecular genetics 8 (8), 1409-1415, 1999
GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry
CJ Ku, T Hosoya, I Maillard, JD Engel
Blood, The Journal of the American Society of Hematology 119 (10), 2242-2251, 2012
C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape
S Dayalan Naidu, A Muramatsu, R Saito, S Asami, T Honda, T Hosoya, ...
Scientific reports 8 (1), 8037, 2018
Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation
N Harada, K Ito, T Hosoya, J Mimura, A Maruyama, N Noguchi, K Yagami, ...
Free Radical Biology and Medicine 53 (12), 2256-2262, 2012
Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice
T Satoh, N Harada, T Hosoya, K Tohyama, M Yamamoto, K Itoh
Biochemical and Biophysical Research Communications 380 (2), 298-302, 2009
Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice
T Hosoya, N Harada, J Mimura, H Motohashi, S Takahashi, O Nakajima, ...
Biochemical and biophysical research communications 365 (3), 562-567, 2008
An NK and T Cell Enhancer Lies 280 Kilobase Pairs 3′ to the Gata3 Structural Gene
S Hosoya-Ohmura, YH Lin, M Herrmann, T Kuroha, A Rao, T Moriguchi, ...
Molecular and cellular biology 31 (9), 1894-1904, 2011
TRIM28 is essential for erythroblast differentiation in the mouse
T Hosoya, M Clifford, R Losson, O Tanabe, JD Engel
Blood, The Journal of the American Society of Hematology 122 (23), 3798-3807, 2013
The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response
A Maruyama, K Nishikawa, Y Kawatani, J Mimura, T Hosoya, N Harada, ...
Biochemical Journal 436 (2), 387-397, 2011
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