Li Chai
Li Chai
Brigham and women's Hospital, Harvard Medicial School
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Patients with cancer appear more vulnerable to SARS-CoV-2: a multicenter study during the COVID-19 outbreak
M Dai, D Liu, M Liu, F Zhou, G Li, Z Chen, Z Zhang, H You, M Wu, ...
Cancer discovery 10 (6), 783-791, 2020
Plasticity of marrow-derived stem cells
EL Herzog, L Chai, DS Krause
Blood 102 (10), 3483-3493, 2003
Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1
J Zhang, WL Tam, GQ Tong, Q Wu, HY Chan, BS Soh, Y Lou, J Yang, ...
Nature cell biology 8 (10), 1114-1123, 2006
Oncofetal Gene SALL4 in Aggressive Hepatocellular Carcinoma
KJ Yong, C Gao, JSJ Lim, B Yan, H Yang, T Dimitrov, A Kawasaki, ...
New England Journal of Medicine 368 (24), 2266-2276, 2013
SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice
Y Ma, W Cui, J Yang, J Qu, C Di, HM Amin, R Lai, J Ritz, DS Krause, ...
Blood 108 (8), 2726-2735, 2006
Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells
J Yang, L Chai, TC Fowles, Z Alipio, D Xu, LM Fink, DC Ward, Y Ma
Proceedings of the National Academy of Sciences 105 (50), 19756-19761, 2008
Overexpression of the HER-2/neu oncogene in pancreatic adenocarcinoma
H Safran, M Steinhoff, S Mangray, R Rathore, TC King, L Chai, K Berzein, ...
American journal of clinical oncology 24 (5), 496-499, 2001
A novel SALL4/OCT4 transcriptional feedback network for pluripotency of embryonic stem cells
J Yang, C Gao, L Chai, Y Ma
PloS one 5 (5), e10766, 2010
Functional antagonism between Sall4 and Plzf defines germline progenitors
RM Hobbs, S Fagoonee, A Papa, K Webster, F Altruda, R Nishinakamura, ...
Cell stem cell 10 (3), 284-298, 2012
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells
J Yang, L Chai, F Liu, LM Fink, P Lin, LE Silberstein, HM Amin, DC Ward, ...
Proceedings of the National Academy of Sciences 104 (25), 10494-10499, 2007
Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex
J Lu, H Jeong, N Kong, Y Yang, J Carroll, HR Luo, LE Silberstein, ...
PloS one 4 (5), e5577, 2009
SALL4 is a key regulator of survival and apoptosis in human leukemic cells
J Yang, L Chai, C Gao, TC Fowles, Z Alipio, H Dang, D Xu, LM Fink, ...
Blood, The Journal of the American Society of Hematology 112 (3), 805-813, 2008
SALL4, the missing link between stem cells, development and cancer
H Tatetsu, NR Kong, G Chong, G Amabile, DG Tenen, L Chai
Gene 584 (2), 111-119, 2016
Differential expression of the novel oncogene, SALL4, in lymphoma, plasma cell myeloma, and acute lymphoblastic leukemia
W Cui, NR Kong, Y Ma, HM Amin, R Lai, L Chai
Modern Pathology 19 (12), 1585-1592, 2006
Myeloid cell-derived reactive oxygen species externally regulate the proliferation of myeloid progenitors in emergency granulopoiesis
HJ Kwak, P Liu, B Bajrami, Y Xu, SY Park, C Nombela-Arrieta, S Mondal, ...
Immunity 42 (1), 159-171, 2015
SALL4 is a new target in endometrial cancer
A Li, Y Jiao, KJ Yong, F Wang, C Gao, B Yan, S Srivastava, GSD Lim, ...
Oncogene 34 (1), 63-72, 2015
Low-expression of microRNA-107 inhibits cell apoptosis in glioma by upregulation of SALL4
J He, W Zhang, Q Zhou, T Zhao, Y Song, L Chai, Y Li
The international journal of biochemistry & cell biology 45 (9), 1962-1973, 2013
Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex
C Gao, T Dimitrov, KJ Yong, H Tatetsu, H Jeong, HR Luo, JE Bradner, ...
Blood, The Journal of the American Society of Hematology 121 (8), 1413-1421, 2013
SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes
HW Jeong, W Cui, Y Yang, J Lu, J He, A Li, D Song, Y Guo, BH Liu, ...
PloS one 6 (4), e18372, 2011
SALL4 is a key transcription regulator in normal human hematopoiesis
C Gao, NR Kong, A Li, H Tatetu, S Ueno, Y Yang, J He, J Yang, Y Ma, ...
Transfusion 53 (5), 1037-1049, 2013
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