Michael P Cancro
Michael P Cancro
Professor of Pathology and Laboratory Medicine, University of Pennsylvania
Verified email at
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Peripheral B cell maturation. II. Heat-stable antigen (hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells.
DM Allman, SE Ferguson, VM Lentz, MP Cancro
Journal of immunology (Baltimore, Md.: 1950) 151 (9), 4431-4444, 1993
A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
Y Hao, P O'Neill, MS Naradikian, JL Scholz, MP Cancro
Blood 118 (5), 1294-1304, 2011
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
M Yan, JR Brady, B Chan, WP Lee, B Hsu, S Harless, M Cancro, ...
Current Biology 11 (19), 1547-1552, 2001
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses
N Pardi, MJ Hogan, MS Naradikian, K Parkhouse, DW Cain, L Jones, ...
Journal of Experimental Medicine 215 (6), 1571-1588, 2018
IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE
S Wang, J Wang, V Kumar, JL Karnell, B Naiman, PS Gross, S Rahman, ...
Nature communications 9 (1), 1758, 2018
Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators
BL Hsu, SM Harless, RC Lindsley, DM Hilbert, MP Cancro
The Journal of Immunology 168 (12), 5993-5996, 2002
Peripheral B cell maturation. I. Immature peripheral B cells in adults are heat-stable antigenhi and exhibit unique signaling characteristics.
DM Allman, SE Ferguson, MP Cancro
Journal of immunology (Baltimore, Md.: 1950) 149 (8), 2533-2540, 1992
The role of B lymphocyte stimulator (BLyS) in systemic lupus erythematosus
MP Cancro, DP D’Cruz, MA Khamashta
The Journal of clinical investigation 119 (5), 1066-1073, 2009
Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling
MJ Walmsley, SKT Ooi, LF Reynolds, SH Smith, S Ruf, A Mathiot, L Vanes, ...
Science 302 (5644), 459-462, 2003
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses
MG Alameh, I Tombácz, E Bettini, K Lederer, S Ndeupen, C Sittplangkoon, ...
Immunity 54 (12), 2877-2892. e7, 2021
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation
R Goenka, LG Barnett, JS Silver, PJ O’Neill, CA Hunter, MP Cancro, ...
The Journal of Immunology 187 (3), 1091-1095, 2011
Tonic B cell antigen receptor signals supply an NF-κB substrate for prosurvival BLyS signaling
JE Stadanlick, M Kaileh, FG Karnell, JL Scholz, JP Miller, WJ Quinn Iii, ...
Nature immunology 9 (12), 1379-1387, 2008
Age-associated B cells
MP Cancro
Annual review of immunology 38, 315-340, 2020
B cells and aging: molecules and mechanisms
MP Cancro, Y Hao, JL Scholz, RL Riley, D Frasca, DK Dunn-Walters, ...
Trends in immunology 30 (7), 313-318, 2009
Role of type I interferons in the activation of autoreactive B cells
K Kiefer, MA Oropallo, MP Cancro, A Marshak‐Rothstein
Immunology and cell biology 90 (5), 498-504, 2012
A B-cell receptor-specific selection step governs immature to mature B cell differentiation
MH Levine, AM Haberman, DB Sant'Angelo, LG Hannum, MP Cancro, ...
Proceedings of the National Academy of Sciences 97 (6), 2743-2748, 2000
BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact
JL Scholz, JE Crowley, MM Tomayko, N Steinel, PJ O'Neill, WJ Quinn III, ...
Proceedings of the National Academy of Sciences 105 (40), 15517-15522, 2008
Age-associated B cells: a T-bet–dependent effector with roles in protective and pathogenic immunity
K Rubtsova, AV Rubtsov, MP Cancro, P Marrack
The Journal of Immunology 195 (5), 1933-1937, 2015
TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells
LS Treml, G Carlesso, KL Hoek, JE Stadanlick, T Kambayashi, RJ Bram, ...
The Journal of Immunology 178 (12), 7531-7539, 2007
A role for IL-27p28 as an antagonist of gp130-mediated signaling
JS Stumhofer, ED Tait, WJQ Iii, N Hosken, B Spudy, R Goenka, ...
Nature immunology 11 (12), 1119-1126, 2010
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