Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding GM Leinninger, YH Jo, RL Leshan, GW Louis, H Yang, JG Barrera, ... Cell metabolism 10 (2), 89-98, 2009 | 488 | 2009 |
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion E Van De Wall, R Leshan, AW Xu, N Balthasar, R Coppari, SM Liu, YH Jo, ... Endocrinology 149 (4), 1773-1785, 2008 | 351 | 2008 |
The geometry of leptin action in the brain: more complicated than a simple ARC MG Myers, H Münzberg, GM Leinninger, RL Leshan Cell metabolism 9 (2), 117-123, 2009 | 348 | 2009 |
Upregulation of insulin receptor substrate-2 in pancreatic β cells prevents diabetes AM Hennige, DJ Burks, U Ozcan, RN Kulkarni, J Ye, S Park, M Schubert, ... The Journal of clinical investigation 112 (10), 1521-1532, 2003 | 342 | 2003 |
Leptin receptor signaling and action in the central nervous system RL Leshan, M Björnholm, H Münzberg, MG Myers Jr Obesity 14 (S8), 208S-212S, 2006 | 261 | 2006 |
Differential accessibility of circulating leptin to individual hypothalamic sites M Faouzi, R Leshan, M Björnholm, T Hennessey, J Jones, ... Endocrinology 148 (11), 5414-5423, 2007 | 231 | 2007 |
Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function M Björnholm, H Münzberg, RL Leshan, EC Villanueva, SH Bates, ... The Journal of clinical investigation 117 (5), 1354-1360, 2007 | 220 | 2007 |
Leptin action through hypothalamic nitric oxide synthase-1–expressing neurons controls energy balance RL Leshan, M Greenwald-Yarnell, CM Patterson, IE Gonzalez, ... Nature medicine 18 (5), 820-823, 2012 | 159 | 2012 |
Direct innervation of GnRH neurons by metabolic-and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus RL Leshan, GW Louis, YH Jo, CJ Rhodes, H Münzberg, MG Myers Journal of Neuroscience 29 (10), 3138-3147, 2009 | 158 | 2009 |
Molecular mapping of mouse brain regions innervated by leptin receptor-expressing cells CM Patterson, RL Leshan, JC Jones, MG Myers Jr Brain research 1378, 18-28, 2011 | 151 | 2011 |
Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine-and amphetamine-regulated transcript neurons of the extended central amygdala RL Leshan, DM Opland, GW Louis, GM Leinninger, CM Patterson, ... Journal of Neuroscience 30 (16), 5713-5723, 2010 | 144 | 2010 |
Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling J Giraud, R Leshan, YH Lee, MF White Journal of Biological Chemistry 279 (5), 3447-3454, 2004 | 122 | 2004 |
Accelerated postnatal growth increases lipogenic gene expression and adipocyte size in low–birth weight mice E Isganaitis, J Jimenez-Chillaron, M Woo, A Chow, J DeCoste, M Vokes, ... Diabetes 58 (5), 1192-1200, 2009 | 101 | 2009 |
Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells X Yi, M Schubert, NS Peachey, K Suzuma, DJ Burks, JA Kushner, ... Journal of Neuroscience 25 (5), 1240-1248, 2005 | 97 | 2005 |
Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling H Münzberg, EE Jobst, SH Bates, J Jones, E Villanueva, R Leshan, ... Journal of Neuroscience 27 (1), 69-74, 2007 | 96 | 2007 |
Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status EC Villanueva, H Munzberg, D Cota, RL Leshan, K Kopp, ... Endocrinology 150 (10), 4541-4551, 2009 | 88 | 2009 |
Leptin does not directly affect CNS serotonin neurons to influence appetite DD Lam, GM Leinninger, GW Louis, AS Garfield, OJ Marston, RL Leshan, ... Cell metabolism 13 (5), 584-591, 2011 | 75 | 2011 |
IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action M Sadagurski, RL Leshan, C Patterson, A Rozzo, A Kuznetsova, ... Cell metabolism 15 (5), 703-712, 2012 | 67 | 2012 |
Leptin signaling modulates the activity of urocortin 1 neurons in the mouse nonpreganglionic Edinger-Westphal nucleus L Xu, WJJM Scheenen, RL Leshan, CM Patterson, CF Elias, S Bouwhuis, ... Endocrinology 152 (3), 979-988, 2011 | 31 | 2011 |
A simple qPCR-based method to detect correct insertion of homologous targeting vectors in murine ES cells GA Soliman, R Ishida-Takahashi, Y Gong, JC Jones, RL Leshan, ... Transgenic research 16, 665-670, 2007 | 26 | 2007 |